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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_0340 [new locus tag: NWMN_RS01925 ]
  • pan locus tag?: SAUPAN001890000
  • symbol: tatA
  • pan gene symbol?: tatA
  • synonym:
  • product: twin-arginine translocation protein TatA

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_0340 [new locus tag: NWMN_RS01925 ]
  • symbol: tatA
  • product: twin-arginine translocation protein TatA
  • replicon: chromosome
  • strand: -
  • coordinates: 390202..390417
  • length: 216
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    ATGATAACTAACACTTTTATTTTAGGCATCACAGGCCCAACAAGTCTTGTCGTCATTAGC
    ATTATCGCTTTAATTATTTTTGGTCCGAAAAAATTACCACAATTTGGCCGTGCCATCGGT
    TCTACTTTAAAAGAATTTAAATCTGCAACAGAAGATTTAGATAAAGAGTCTCACGATACA
    CCCAGTAAGGAATCGAAACAACAGCGAGAGCAATAG
    60
    120
    180
    216

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_0340 [new locus tag: NWMN_RS01925 ]
  • symbol: TatA
  • description: twin-arginine translocation protein TatA
  • length: 71
  • theoretical pI: 9.23936
  • theoretical MW: 7801.96
  • GRAVY: -0.192958

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtwin arginine-targeting protein translocase, TatA/E family (TIGR01411; HMM-score: 68)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtwin arginine-targeting protein translocase TatB (TIGR01410; HMM-score: 34.4)
  • TheSEED:  
    Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related Twin-arginine translocation protein TatAy 
    Twin-arginine translocation system Twin-arginine translocation protein TatAy 
  • PFAM:
    no clan definedMttA_Hcf106; mttA/Hcf106 family (PF02416; HMM-score: 68.7)
    DUF1510; Protein of unknown function (DUF1510) (PF07423; HMM-score: 13.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.17
    • Cytoplasmic Membrane Score: 9.51
    • Cellwall Score: 0.16
    • Extracellular Score: 0.15
    • Internal Helix: 1
  • LocateP: N-terminally anchored (No CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -0.5
    • N-terminally Anchored Score: 2
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.182
    • Ymax_pos: 39
    • Cmax: 0.183
    • Cmax_pos: 24
    • Smax: 0.381
    • Smax_pos: 7
    • Smean: 0.226
    • D: 0.199
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MITNTFILGITGPTSLVVISIIALIIFGPKKLPQFGRAIGSTLKEFKSATEDLDKESHDTPSKESKQQREQ

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator: NWMN_1406 (Fur*)
    Fur* (TF) important in Iron homeostasis  RegPrecise

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]