From AureoWiki
Jump to navigation Jump to search

NCBI: 06-JUL-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_0702 [new locus tag: NWMN_RS03980 ]
  • pan locus tag?: SAUPAN002636000
  • symbol: NWMN_0702
  • pan gene symbol?: sstA
  • synonym:
  • product: ferrichrome ABC transporter permease

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_0702 [new locus tag: NWMN_RS03980 ]
  • symbol: NWMN_0702
  • product: ferrichrome ABC transporter permease
  • replicon: chromosome
  • strand: +
  • coordinates: 788526..789497
  • length: 972
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAAGTATTTATTAAAGGGAAATATTTTGCTTCTATTACTAATATTGTTGACAATTATT
    TCGTTGTTCATAGGTGTGAGTGAACTATCAATTAAAGATTTACTACATTTAACTGAGTCA
    CAGCGGAATATTTTATTCTCAAGCCGAATACCAAGGACGATGAGTATTTTAATTGCTGGA
    AGTTCGTTGGCTTTAGCAGGCTTGATAATGCAACAAATGATGCAAAATAAGTTTGTTAGT
    CCGACTACAGCTGGAACGATGGAATGGGCTAAACTAGGTATTTTAATTGCTTTATTGTTC
    TTTCCAACCGGTCATATTTTATTAAAACTAGTATTTGCTGTTATTTGCAGTATTTGCGGT
    ACGTTTTTATTTGTTAAAATCATTGATTTTATAAAAGTGAAAGATGTCATTTTTGTACCG
    CTTTTAGGAATTATGATGGGTGGGATTGTTGCAAGTTTCACAACCTTCATCTCATTGCGC
    ACGAATGCTGTTCAAAGCATTGGTAACTGGCTTAACGGGAACTTTGCCATTATCACAAGT
    GGACGCTATGAAATTTTATATTTAAGTATTCCTCTTTTAGCATTGACATATCTTTTTGCT
    AATCATTTCACGATTGTAGGAATGGGTAAAGACTTTACTAATAATTTAGGTTTGAGTTAC
    GAAAAATTAATTAACATCGCATTGTTTATTACTGCAACTATTACAGCATTGGTAGTGGTG
    ACTGTTGGAACATTACCGTTCTTAGGACTAGTAATACCAAATATTATTTCAATTTATCGA
    GGTGATCATTTGAAAAATGCTATCCCTCATACGATGATGTTAGGTGCCATCTTTGTATTA
    TTTTCTGATATAGTTGGCAGAATTGTTGTTTATCCATATGAAATAAATATTGGTTTAACA
    ATAGGTGTATTTGGAACAATCATTTTCCTTATCTTGCTTATGAAAGGTAGGAAAAATTAT
    GCGCAACAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    972

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_0702 [new locus tag: NWMN_RS03980 ]
  • symbol: NWMN_0702
  • description: ferrichrome ABC transporter permease
  • length: 323
  • theoretical pI: 10.1221
  • theoretical MW: 35581.9
  • GRAVY: 1.00279

Function[edit | edit source]

  • TIGRFAM:
    proposed F420-0 ABC transporter, permease protein (TIGR03869; HMM-score: 93.3)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    Membrane_trans (CL0142) FecCD; FecCD transport family (PF01032; HMM-score: 214.1)
    and 1 more
    no clan defined DUF2367; Uncharacterized conserved protein (DUF2367) (PF10164; HMM-score: 13.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.036831
    • TAT(Tat/SPI): 0.000302
    • LIPO(Sec/SPII): 0.035584
  • predicted transmembrane helices (TMHMM): 8

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator: Fur* (repression) regulon
    Fur*(TF)important in Iron homeostasis; RegPrecise 

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]