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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1447 [new locus tag: NWMN_RS08165 ]
  • pan locus tag?: SAUPAN004122000
  • symbol: NWMN_1447
  • pan gene symbol?: comGB
  • synonym:
  • product: competence protein ComGB-like protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_1447 [new locus tag: NWMN_RS08165 ]
  • symbol: NWMN_1447
  • product: competence protein ComGB-like protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1615073..1616143
  • length: 1071
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    GTGAAACTACAATGCATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAG
    GCCCAACAAATCGACTTACTTTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTG
    TATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATAAAAATAAGCAATTAGGTACC
    ACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAAATATTATCACTGATAGGT
    TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGAC
    GTTCTAGAAGAAACCGTAAATTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTA
    AAGACACTGCAATACCCCTTAATACTAGTTTCTATCTTTATTGCTATGATTATTATATTA
    AACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
    TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATG
    CTCATAATAGTATCTATGTTGGCTATTATTATGAAATTAATTTATAACAATTTAAATATG
    CTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATATCAGGCTATTTCCAATTATTT
    AAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
    TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAA
    TACTTATTAACTTATTCAGAAATGGGATATGGTTTGCCTCAAATTTTAGAAAAACTAAAA
    TGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTGAAAAGAGAGGGAAGCTAGAA
    GTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
    CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATT
    TATTTAGTAATTATGTTACCAATGTTTCAAATGATGCAAAGTATAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1071

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_1447 [new locus tag: NWMN_RS08165 ]
  • symbol: NWMN_1447
  • description: competence protein ComGB-like protein
  • length: 356
  • theoretical pI: 10.0111
  • theoretical MW: 41364.5
  • GRAVY: 0.410674

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype II secretion system protein F (TIGR02120; HMM-score: 95.2)
  • TheSEED:  
    DNA MetabolismDNA uptake, competenceGram Positive Competence Late competence protein ComGB, access of DNA to ComEA 
    DNA uptake, competenceLate competence Late competence protein ComGB, access of DNA to ComEA 
  • PFAM:
    no clan definedT2SSF; Type II secretion system (T2SS), protein F (PF00482; HMM-score: 81.2)
    E1-E2_ATPase; E1-E2 ATPase (PF00122; HMM-score: 9.3)
    DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 6.1)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.224
    • Ymax_pos: 13
    • Cmax: 0.128
    • Cmax_pos: 22
    • Smax: 0.629
    • Smax_pos: 5
    • Smean: 0.508
    • D: 0.335
  • predicted transmembrane helices (TMHMM): 3

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKLQCINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIGYSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLSSFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQSIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIKQTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]