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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1688
  • pan locus tag?: SAUPAN004513000
  • symbol: NWMN_1688
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_1688
  • symbol: NWMN_1688
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1883505..1883957
  • length: 453
  • essential: unknown

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAAAATAACATATAAATATAGAGGAGATTTACCTTTGAATACAGAGAACAACAAGAAT
    CAAAACCAATCTGTTAAAAATTCTGAAAGACGCGGCATGTTAAAAGGATGCGGCGGTTGC
    CTTATTTCTTTTATTTTATTAATAATCTTATTATCAGCCTGTTCAATGATGTTTAGTAAT
    AATGACAATTCCACTAATAATCAATCATCAAAAACGCAATTAACTCAAAAAGATGAAAAT
    AAAAATGAAGATAAGCCTGAGGAAAAATCAGAAACAGCAACAGATGAGGATTTACAATCA
    ACCGAAGAAGTACCTGCAAATGAAAATACTGAAAATAATCAACATGAAATTGATGAAATA
    ACAACAAAAGATCAATCAGACGATGATATTAACACACCAAACGTTGCAGAAGATAAATCA
    CAAGACGACTTGAAAGATGATTTAAAAGAATAG
    60
    120
    180
    240
    300
    360
    420
    453

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_1688
  • symbol: NWMN_1688
  • description: hypothetical protein
  • length: 150
  • theoretical pI: 4.12325
  • theoretical MW: 16965.3
  • GRAVY: -1.26

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    TIGR03943 family protein (TIGR03943; HMM-score: 14.9)
    MetabolismTransport and binding proteinsNucleosides, purines and pyrimidinesnucleoside Transporter (TIGR00939; HMM-score: 14.1)
    Cellular processesCellular processesSporulation and germinationstage III sporulation protein AG (TIGR02830; HMM-score: 14.1)
    Cellular processesCellular processesPathogenesistype III secretion protein, HrcV family (TIGR01399; HMM-score: 13.8)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype III secretion protein, HrcV family (TIGR01399; HMM-score: 13.8)
    Cellular processesCellular processesCell divisioncell division protein FtsL (TIGR02209; HMM-score: 13.3)
    Cellular processesCellular processesSporulation and germinationstage III sporulation protein AF (TIGR02896; HMM-score: 10.5)
    MetabolismTransport and binding proteinsOtherpleiotropic drug resistance family protein (TIGR00956; HMM-score: 8.8)
    Cellular processesCellular processesSporulation and germinationsporulation lipoprotein, YhcN/YlaJ family (TIGR02898; HMM-score: 7.2)
    mycoides cluster lipoprotein, LppA/P72 family (TIGR03490; HMM-score: 5.6)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype VII secretion protein EssA (TIGR03927; HMM-score: 4.6)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersHeme, porphyrin, and cobalamincobaltochelatase, CobT subunit (TIGR01651; EC 6.6.1.2; HMM-score: 3.4)
  • TheSEED:  
    Hypothetical protein SAV1799 
  • PFAM:
    no clan definedDUF1510; Protein of unknown function (DUF1510) (PF07423; HMM-score: 20.5)
    CRA; Circumsporozoite-related antigen (CRA) (PF06589; HMM-score: 19.4)
    DMT (CL0184) Zip; ZIP Zinc transporter (PF02535; HMM-score: 17.5)
    no clan definedDUF4692; Domain of unknown function (DUF4692) (PF15763; HMM-score: 17)
    GPCR_A (CL0192) SID-1_RNA_chan; dsRNA-gated channel SID-1 (PF13965; HMM-score: 16.9)
    O-anti_assembly (CL0499) O-antigen_lig; O-antigen ligase like membrane protein (PF13425; HMM-score: 16.5)
    no clan definedTMEM51; Transmembrane protein 51 (PF15345; HMM-score: 15.9)
    SARAF; SOCE-associated regulatory factor of calcium homoeostasis (PF06682; HMM-score: 15.7)
    Piezo_RRas_bdg; Piezo non-specific cation channel, R-Ras-binding domain (PF12166; HMM-score: 14.3)
    MAP17; Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 (PF15807; HMM-score: 12.7)
    Serinc; Serine incorporator (Serinc) (PF03348; HMM-score: 12.3)
    G0-G1_switch_2; G0/G1 switch protein 2 (PF15103; HMM-score: 11.9)
    FAM176; FAM176 family (PF14851; HMM-score: 11.7)
    V_ATPase_I; V-type ATPase 116kDa subunit family (PF01496; HMM-score: 11.4)
    DUF4834; Domain of unknown function (DUF4834) (PF16118; HMM-score: 10.9)
    CLN3; CLN3 protein (PF02487; HMM-score: 10.4)
    DMT (CL0184) CSG2; Ceramide synthase regulator (PF16965; HMM-score: 10)
    no clan definedTRAP_alpha; Translocon-associated protein (TRAP), alpha subunit (PF03896; HMM-score: 9.7)
    DUF4820; Domain of unknown function (DUF4820) (PF16091; HMM-score: 9.7)
    Viral_ssRNA_CP (CL0055) TT_ORF1; TT viral orf 1 (PF02956; HMM-score: 9.5)
    Peptidase_AD (CL0130) Presenilin; Presenilin (PF01080; HMM-score: 9.3)
    DMT (CL0184) Ureide_permease; Ureide permease (PF07168; HMM-score: 9.1)
    APC (CL0062) HCO3_cotransp; HCO3- transporter family (PF00955; HMM-score: 8.8)
    NPR (CL0435) NPR3; Nitrogen Permease regulator of amino acid transport activity 3 (PF03666; HMM-score: 8.6)
    MFS (CL0015) Folate_carrier; Reduced folate carrier (PF01770; HMM-score: 8.1)
    FUSC (CL0307) ALMT; Aluminium activated malate transporter (PF11744; HMM-score: 5.1)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • LocateP: Lipid anchored
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPII)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: LLSACSM
  • SignalP: no predicted signal peptide
    • Ymax: 0.298
    • Ymax_pos: 62
    • Cmax: 0.182
    • Cmax_pos: 62
    • Smax: 0.738
    • Smax_pos: 52
    • Smean: 0.299
    • D: 0.298
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKITYKYRGDLPLNTENNKNQNQSVKNSERRGMLKGCGGCLISFILLIILLSACSMMFSNNDNSTNNQSSKTQLTQKDENKNEDKPEEKSETATDEDLQSTEEVPANENTENNQHEIDEITTKDQSDDDINTPNVAEDKSQDDLKDDLKE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]