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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1736 [new locus tag: NWMN_RS09780 ]
  • pan locus tag?: SAUPAN004774000
  • symbol: NWMN_1736
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_1736 [new locus tag: NWMN_RS09780 ]
  • symbol: NWMN_1736
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1937045..1938241
  • length: 1197
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGTTAAATTTATTCATTGTTCGGATTTACATTTAGATAGTCCTTTCAAATCTAAGAGT
    CATATAAGCCCTAAAATTTTTGAGGATGTTCAAAAAAGTGCTTATGAAAGTTTTAAAAAT
    ATTGTAGATATTGCATTACAACAAGATGTTGATTTTGTAATTATCGCGGGTGATTTATTT
    GATAGTGAAAACAGAACATTACGTGCTGAAATTTTCTTAAAACAGCAATTTGAACGTTTA
    CAAAATGAACAAATCTTTGTTTATGTTTGTCATGGTAATCACGATCCTTTATCATCAAAG
    ATTTCATCAAACTGGCCAGATAATGTTTCTGTATTTTCAAATAAAGTTGAGACGTATGAA
    GCAATTACTAAATCTGGTGAAACAATTTATATTCACGGATTTAGTTATGAAAATAGAGCA
    AGTTATGAGAACAAGATTGATGAATATCCATCAAGTCAAGGCCAAAAAGGCATACATATT
    GGTGTCTTGCATGGTACGTATAGTAAATCTTCAGTTAACGAAAGATATACCGAGTTCATT
    TTAGAAGATTTAAACAGTAAATTGTATCATTATTGGGCTTTAGGTCATATACATGAACGT
    CAACAATTAAGTGATATGCCTGTAATTAACTATTCAGGTAATATTCAAGGTAGACATTTT
    AATGAGCAAGGTGAAAAAGGTTGCTTATTAATCGAGGGTGACCACTTAAAATTAAAGACT
    AAATTTTATCCTACACAGTATATTAGATTTGAAGAAGCAACTATTGAAACGGATAAGACA
    TCTAAGCAAGGTTTATACGAGGTCATTCAAAACTTTAAAGAACAAGTGAGAGAAGAAGGA
    AAAGCCTTTTATCGTTTAACGCTTGTTATTAATAGTGAGACATTAATTTCACCTCAAGAT
    TTATTACAAGTTGAAGAAATGATTACAGATTATGAAGAAAACGAAAATCAATTTGTATAT
    ATTGATGAGTTAAAAATACAATATGCACAAAATGATGAGTCACCTTTAGTTAATGAATTT
    TCAGCGGAATTATTAGTCGATCAAACTGTTTTTGATAAAGCGATGTCAGATTTATATTTA
    AATCCAAGGGCATCTAAGTTCCTAGACGATTATGGAACATTCGACCATACAGCATTAGTT
    AATCGTGCTGAAGAAATATTAAAAGCTGAAATGAGAGGTGAACAAAATGATAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1197

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_1736 [new locus tag: NWMN_RS09780 ]
  • symbol: NWMN_1736
  • description: hypothetical protein
  • length: 398
  • theoretical pI: 4.63383
  • theoretical MW: 46224.1
  • GRAVY: -0.586181

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingDNA metabolismDNA replication, recombination, and repairexonuclease SbcCD, D subunit (TIGR00619; HMM-score: 60.3)
    metallophosphoesterase, DNA ligase-associated (TIGR04123; HMM-score: 20.7)
    putative phosphoesterase (TIGR03729; HMM-score: 20)
    Genetic information processingDNA metabolismDNA replication, recombination, and repairDNA repair protein (mre11) (TIGR00583; HMM-score: 19.9)
    Unknown functionEnzymes of unknown specificityphosphodiesterase, MJ0936 family (TIGR00040; EC 3.1.-.-; HMM-score: 15.3)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersThiaminehydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase (TIGR00097; EC 2.7.1.49,2.7.4.7; HMM-score: 10.8)
  • TheSEED:  
    DNA MetabolismDNA repairDNA repair, bacterial DNA repair exonuclease family protein YhaO 
  • PFAM:
    Calcineurin (CL0163) Metallophos; Calcineurin-like phosphoesterase (PF00149; HMM-score: 53)
    Metallophos_2; Calcineurin-like phosphoesterase superfamily domain (PF12850; HMM-score: 41)
    no clan definedDUF835; Protein of unknown function (DUF835) (PF05763; HMM-score: 18.5)
    Chelatase (CL0043) CbiK; Cobalt chelatase (CbiK) (PF06180; HMM-score: 13.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.159
    • Ymax_pos: 19
    • Cmax: 0.116
    • Cmax_pos: 23
    • Smax: 0.313
    • Smax_pos: 10
    • Smean: 0.211
    • D: 0.18
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MVKFIHCSDLHLDSPFKSKSHISPKIFEDVQKSAYESFKNIVDIALQQDVDFVIIAGDLFDSENRTLRAEIFLKQQFERLQNEQIFVYVCHGNHDPLSSKISSNWPDNVSVFSNKVETYEAITKSGETIYIHGFSYENRASYENKIDEYPSSQGQKGIHIGVLHGTYSKSSVNERYTEFILEDLNSKLYHYWALGHIHERQQLSDMPVINYSGNIQGRHFNEQGEKGCLLIEGDHLKLKTKFYPTQYIRFEEATIETDKTSKQGLYEVIQNFKEQVREEGKAFYRLTLVINSETLISPQDLLQVEEMITDYEENENQFVYIDELKIQYAQNDESPLVNEFSAELLVDQTVFDKAMSDLYLNPRASKFLDDYGTFDHTALVNRAEEILKAEMRGEQNDN

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]