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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1933 [new locus tag: NWMN_RS11150 ]
  • pan locus tag?: SAUPAN005239000
  • symbol: NWMN_1933
  • pan gene symbol?:
  • synonym:
  • product: acetyltransferase, GNAT family protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_1933 [new locus tag: NWMN_RS11150 ]
  • symbol: NWMN_1933
  • product: acetyltransferase, GNAT family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2141602..2142054
  • length: 453
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    GTGGGTTATATGAGCATAATTACAAGATTGTTTAATAACAGTGATTTTGAAAAATTAAAT
    CAACTATGTAAATTATATGATGATCTAGGTTATCCAACAAATGAGAATGATTTAAAAAAG
    AGACTAAAGAAAATAACGAATCATGATGATTACTTCCTACTGCTTTTGATAAAAGAAAAT
    AAAATAATTGGTTTAAGTGGTATGTGTAAAATGATGTTTTACGAAAAAAATGCAGAGTAT
    ATGAGAATCCTTGCGTTTGTTATACATTCTGAATTTAGGAAAAAAGGTTATGGAAAGAGA
    TTATTAGCTGATTCTGAAGAATTTTCTAAACGGTTGAATTGTAAAGCAATAACACTAAAT
    AGTGGTAATAGAAATGAAAGACTATCTGCACATAAACTATATAGTGATAATGGGTATGTT
    AGCAATACATCTGGGTTTACTAAACAACTATAA
    60
    120
    180
    240
    300
    360
    420
    453

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_1933 [new locus tag: NWMN_RS11150 ]
  • symbol: NWMN_1933
  • description: acetyltransferase, GNAT family protein
  • length: 150
  • theoretical pI: 9.75545
  • theoretical MW: 17547.2
  • GRAVY: -0.547333

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein synthesisRibosomal proteins: synthesis and modificationribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 33.6)
    putative beta-lysine N-acetyltransferase (TIGR03827; EC 2.3.1.-; HMM-score: 18.8)
    Cell structureCell envelopeBiosynthesis and degradation of murein sacculus and peptidoglycanN-acetylmuramoyl-L-alanine amidase CwlD (TIGR02883; EC 3.5.1.28; HMM-score: 13.2)
    Cellular processesCellular processesSporulation and germinationN-acetylmuramoyl-L-alanine amidase CwlD (TIGR02883; EC 3.5.1.28; HMM-score: 13.2)
    Genetic information processingTranscriptionDNA-dependent RNA polymeraseradical SAM enzyme/protein acetyltransferase, ELP3 family (TIGR01211; EC 2.3.1.48; HMM-score: 12.1)
  • TheSEED:  
    Acetyltransferase, GNAT family 
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 45.2)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 34.1)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 31.9)
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 18.3)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 17.7)
    Acetyltransf_15; Putative acetyl-transferase (PF17013; HMM-score: 16.1)
    DUF3749; Acetyltransferase (GNAT) domain (PF12568; HMM-score: 11.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.118
    • Ymax_pos: 26
    • Cmax: 0.103
    • Cmax_pos: 20
    • Smax: 0.173
    • Smax_pos: 16
    • Smean: 0.115
    • D: 0.117
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MGYMSIITRLFNNSDFEKLNQLCKLYDDLGYPTNENDLKKRLKKITNHDDYFLLLLIKENKIIGLSGMCKMMFYEKNAEYMRILAFVIHSEFRKKGYGKRLLADSEEFSKRLNCKAITLNSGNRNERLSAHKLYSDNGYVSNTSGFTKQL

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor: SigB [1] other strains
    SigB (sigma factor) controls a large regulon involved in stress/starvation response and adaptation
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]