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NCBI: 06-JUL-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2302 [new locus tag: NWMN_RS13235 ]
  • pan locus tag?: SAUPAN005934000
  • symbol: NWMN_2302
  • pan gene symbol?:
  • synonym:
  • product: acetyltransferase, GNAT family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2302 [new locus tag: NWMN_RS13235 ]
  • symbol: NWMN_2302
  • product: acetyltransferase, GNAT family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2530440..2530976
  • length: 537
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGACAAAAACGATGATTCGACTCGCAAGTGAACAAGATGCAGAAAAATTGCAACAACTC
    ATGCATGAAGCATTTACGCCTCTAAGAGAACTAGGTATTGATTGGCCTTCGGTTAATGCT
    AATTTAGATGCTGTTAAAGAAAATATAGATAAAAATACTACATTTGTCATGACAATTGAT
    GATGAAATTATATCTACGATTACGGTTAGATATCCTTGGGGAAGTGTGAAAAGTATTTCG
    GGTTATCCTTTTGTCTGGTGGTTTGCGACAAATCCTGAGTATGAAGGGAAAGGCTATGGT
    AGCCAATTACTTACTTATGTTGAAGAAGCATTTTTGCGAGATACGTTAAAGTCAGCGGCA
    GTTACTTTAGGTACATCTGCAAGATTGCATCCGTGGTTACTTAAAATTTATGAAAAAAGA
    GGTTATGAAATATACAGCGAACATGAAAATGATGATGGCGATTTAGGTGTGATCATGCGC
    AAAGTATTGATACCCGAGCGCTTTGACGAAACAATATTAGGCCAACCACCATTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    537

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_2302 [new locus tag: NWMN_RS13235 ]
  • symbol: NWMN_2302
  • description: acetyltransferase, GNAT family protein
  • length: 178
  • theoretical pI: 4.57447
  • theoretical MW: 20425.1
  • GRAVY: -0.319663

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 12.3)
    putative beta-lysine N-acetyltransferase (TIGR03827; EC 2.3.1.-; HMM-score: 11.9)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 34.9)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 34.9)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 34.2)
    and 3 more
    Acetyltransf_9; Acetyltransferase (GNAT) domain (PF13527; HMM-score: 26.1)
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 12.9)
    GNAT_acetyltr_2; GNAT acetyltransferase 2 (PF13718; HMM-score: 12.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003603
    • TAT(Tat/SPI): 0.000388
    • LIPO(Sec/SPII): 0.000444
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MTKTMIRLASEQDAEKLQQLMHEAFTPLRELGIDWPSVNANLDAVKENIDKNTTFVMTIDDEIISTITVRYPWGSVKSISGYPFVWWFATNPEYEGKGYGSQLLTYVEEAFLRDTLKSAAVTLGTSARLHPWLLKIYEKRGYEIYSEHENDDGDLGVIMRKVLIPERFDETILGQPPF

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]