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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2370 [new locus tag: NWMN_RS13655 ]
  • pan locus tag?: SAUPAN006037000
  • symbol: NWMN_2370
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_2370 [new locus tag: NWMN_RS13655 ]
  • symbol: NWMN_2370
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2607919..2609457
  • length: 1539
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGACATCAAAACATCAACAAAAGGGGTCTATCGTCAATCGTTTCTTGAATAGTGTTGAA
    AAAATCGGAAATAAATTGCCAGATCCTAGCGTCTTATTCTTTTTAATGTGTGTGGGCTTA
    GCCATTATGACATGGGTTATCTCATTATTTAATGTATCTGTTAAGCATCCAGGTACGCAT
    CAAACCATTTATATTAAAAATATAATTAGCCATGATGGATTTACGATGATAATGAATGAT
    ACGATTAAAAATTTCTCAGAGTTCCCAGCATTAGGCTTAGTACTAGCAGTGATGATTGGT
    ATTGGTGTTGCAGAGAAAACAGGATACTTCGATAAGTTAATGATTTCTGTTGTGAATCGC
    GCACCACGTTTCTTAATTTTACCGACTATTATATTAATTGGTATTTTAGGTAGTACAGCC
    GGCGATGCTGCGACAATTATCTTGCCGCCGCTTGCAGCAATGCTTTTTATTAAAATTGGC
    TATCACCCTATCGCTGGACTAACGATGGCATATGCTTCCGCTGTTGGAGGATTTGCAGCA
    AATATAGTTGTTGGTATGCAAGATGCTTTGGTCTATTCATTTACAGAACCGGCAACACGT
    ATCGTTTCAGATTCTATTAAAACAAACGTTGCTATGAACTGGTACTTTATCGCAGCGAGT
    GTCGTTGTATTACTTCCTACGATATTGCTAGTTACAACTAAGCTCATTATTCCTAGATTA
    GGAAAATATGATGACAGTTTAATGCATGATGACCATGAAGAAACATCTTCACATATTACT
    GACAAAGAAGCACATGCTTTAAAATGGGCAAATATCAGTTTCATAGTCACAATTATTTTA
    TTAATTATTACAGCCATTCCTGAACATAGCTTTTTAAGAAATGCTAAAACAGGCAGCTTA
    CTAGACGATGCGCCATTAATTAACGGTGTCGGATTAATTATTCTTGTCGTATTTTTAGTA
    CCTGGATTAGTTTATGGGATTTTAAGCAAAGAAATTAAAAATACAAAAGACTTAGGTAAA
    ATGTTCGGCGATGCTGTAGGATCAATGGGAACATTTATCGTTATTGTGTTTTTTGCAGCA
    CAGCTACTTGCGTATTTAAAGTGGAGTAATTTAGGAATTATCGCTGCTGTTAAAGGTGCC
    AAATTATTAGAACATCAAAACGGTATTGTATTGATACTAGGTATTATTGTACTGAGTGCA
    ATGGTCAACATGTTAATCGGAAGCGCATCGGCTAAATGGGGTATTTTAGGACCGATATTC
    GTACCAATGTTAATCCTTATCGGCTTTCATCCCGCATTCACACAAGTCATTTACCGTGTA
    GGCGATTCAATTACCAATCCAATTACACCGATGATGCCGTACTTACCTTTATTATTAACT
    TATGCACAAAAATACGATAAACGCATGAAACTCGGAGCCTTACTTTCTAGTTTAATGCCG
    TATTCAATCGCGCTAAGTATTGTATGGACAGTATTTGTCATCATTTGGTTCCTATTAGGT
    ATCCCTGTTGGACCAGGTGGACCGATATTCGTTAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1539

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_2370 [new locus tag: NWMN_RS13655 ]
  • symbol: NWMN_2370
  • description: hypothetical protein
  • length: 512
  • theoretical pI: 9.7071
  • theoretical MW: 55574.3
  • GRAVY: 0.775391

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Hypothetical proteinsConservedAbgT transporter family (TIGR00819; HMM-score: 447.5)
  • TheSEED:  
    Aminobenzoyl-glutamate transport protein 
  • PFAM:
    IT (CL0182) ABG_transport; AbgT putative transporter family (PF03806; HMM-score: 726.3)
    DcuC; C4-dicarboxylate anaerobic carrier (PF03606; HMM-score: 26.3)
    Na_H_antiporter; Na+/H+ antiporter family (PF03553; HMM-score: 25.4)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 11
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.172
    • Ymax_pos: 56
    • Cmax: 0.116
    • Cmax_pos: 56
    • Smax: 0.346
    • Smax_pos: 50
    • Smean: 0.164
    • D: 0.169
  • predicted transmembrane helices (TMHMM): 12

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MTSKHQQKGSIVNRFLNSVEKIGNKLPDPSVLFFLMCVGLAIMTWVISLFNVSVKHPGTHQTIYIKNIISHDGFTMIMNDTIKNFSEFPALGLVLAVMIGIGVAEKTGYFDKLMISVVNRAPRFLILPTIILIGILGSTAGDAATIILPPLAAMLFIKIGYHPIAGLTMAYASAVGGFAANIVVGMQDALVYSFTEPATRIVSDSIKTNVAMNWYFIAASVVVLLPTILLVTTKLIIPRLGKYDDSLMHDDHEETSSHITDKEAHALKWANISFIVTIILLIITAIPEHSFLRNAKTGSLLDDAPLINGVGLIILVVFLVPGLVYGILSKEIKNTKDLGKMFGDAVGSMGTFIVIVFFAAQLLAYLKWSNLGIIAAVKGAKLLEHQNGIVLILGIIVLSAMVNMLIGSASAKWGILGPIFVPMLILIGFHPAFTQVIYRVGDSITNPITPMMPYLPLLLTYAQKYDKRMKLGALLSSLMPYSIALSIVWTVFVIIWFLLGIPVGPGGPIFVK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_2370 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator: CodY
    CodY (TF) important in Amino acid metabolismRegPrecise

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]