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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2471 [new locus tag: NWMN_RS14195 ]
  • pan locus tag?: SAUPAN006240000
  • symbol: NWMN_2471
  • pan gene symbol?:
  • synonym:
  • product: TetR family regulatory protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_2471 [new locus tag: NWMN_RS14195 ]
  • symbol: NWMN_2471
  • product: TetR family regulatory protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2720923..2721510
  • length: 588
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGTTAGGTAGTGAACAAATGATGGAAAGTAAATCCATAGATCCAAGAATCGTTAGAACC
    AAACAATTGCTTGTCGATGCTTTTCTTAAAATTTCTAGAGAAAAGAAATTATCTCAAATT
    ACAGTTAAAGATATCACTGATATTGCTACGCTAAATCGTGCAACATTTTACGCTCATTTC
    ACTGATAAAGAAGACCTCCTAGACTACACATTATCTGTAACCATTTTAAAAGACTTGAAT
    GATAATTTGAGCATTTCTAATGTCATTAATGAAAAGGTTCTGCGTAATATTTTCATTTCA
    ATTGCGAGTTATATCAAAGATGCTGCAAAGTCTTGCGAATTAAATAGTGAAGCATTTTGC
    AACAAAGCACATCAACGTATTAATAATGAATTAGAAGATATTTTTGCGATTATGTTAGAA
    AACAGCTATCCGGAGCATCAACGAGATATCATTGTAAATAGTGCGAGTTTTTTAGCAGCT
    GGTATCTCAGGCTTAGCATTACATTGGTTTAACACGAGTCAAGAGACAGCCGATGTGTTT
    ATCGATCGCAACCTTCCATTTTTAATTCATCATATAGCACATTTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    588

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_2471 [new locus tag: NWMN_RS14195 ]
  • symbol: NWMN_2471
  • description: TetR family regulatory protein
  • length: 195
  • theoretical pI: 5.8754
  • theoretical MW: 22231.3
  • GRAVY: -0.0733333

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    probable dihydroxyacetone kinase regulator (TIGR02366; HMM-score: 40.3)
    Signal transductionRegulatory functionsDNA interactionstranscriptional repressor BetI (TIGR03384; HMM-score: 20.4)
    Signal transductionRegulatory functionsDNA interactionsmycofactocin system transcriptional regulator (TIGR03968; HMM-score: 16.4)
  • TheSEED:  
    CBSS-196620.1.peg.2477 TetR family regulatory protein 
  • PFAM:
    HTH (CL0123) TetR_N; Bacterial regulatory proteins, tetR family (PF00440; HMM-score: 27.7)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helix: 1
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.125
    • Ymax_pos: 13
    • Cmax: 0.109
    • Cmax_pos: 59
    • Smax: 0.202
    • Smax_pos: 9
    • Smean: 0.152
    • D: 0.135
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MLGSEQMMESKSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIATLNRATFYAHFTDKEDLLDYTLSVTILKDLNDNLSISNVINEKVLRNIFISIASYIKDAAKSCELNSEAFCNKAHQRINNELEDIFAIMLENSYPEHQRDIIVNSASFLAAGISGLALHWFNTSQETADVFIDRNLPFLIHHIAHF

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]