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NCBI: 06-JUL-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2560 [new locus tag: NWMN_RS14695 ]
  • pan locus tag?: SAUPAN006406000
  • symbol: NWMN_2560
  • pan gene symbol?:
  • synonym:
  • product: acetyltransferase, GNAT family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2560 [new locus tag: NWMN_RS14695 ]
  • symbol: NWMN_2560
  • product: acetyltransferase, GNAT family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2828324..2828824
  • length: 501
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGGTATTAAGAAAAGTAATCATGCAGGACTTAGATCAAATTATTGCACTTGAAAATATT
    GGTTTTTCACCGGAAGAAGCTGCAACACGAGAGGCATTGAAATTGAGAATTGAACAAATT
    CAAGAAACTTTTATTGTAGCTGAAAAGAATGATGAAGTAATTGGATACATCAACGGTCCA
    GTCATAAAAGAGCGTTACATTAGCGATGATTTATTTAAAAATGTCTCCACAAATAATAGT
    GAAGGTGGCTATATTAGTGTGTTAGGTCTTGTTGTAGCACCAAATTATCAAGGTCAGGGT
    ATTGCAGGTCGCTTACTAAACTATTTTGAAACTCTTGCTAAGAATCATCATCGACATGGT
    GTAACGTTAACATGTCGAGAATCATTAATTTCATTTTATGAAAAATATGGGTATCGTAAT
    GAAGGTGTATCAGAATCATGTCATGGCGGTATTAAATGGTATAACCTTGTTAAAAATATA
    AAAAAGGATGATGAGGTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    501

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_2560 [new locus tag: NWMN_RS14695 ]
  • symbol: NWMN_2560
  • description: acetyltransferase, GNAT family protein
  • length: 166
  • theoretical pI: 5.6809
  • theoretical MW: 18827.2
  • GRAVY: -0.316867

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 49.6)
    and 1 more
    Genetic information processing Transcription DNA-dependent RNA polymerase radical SAM enzyme/protein acetyltransferase, ELP3 family (TIGR01211; EC 2.3.1.48; HMM-score: 12.8)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 57.4)
    Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 56.6)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 50)
    and 5 more
    Acetyltransf_9; Acetyltransferase (GNAT) domain (PF13527; HMM-score: 31.7)
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 19.5)
    Acetyltransf_15; Putative acetyl-transferase (PF17013; HMM-score: 18.7)
    Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 15.6)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 13.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00244
    • TAT(Tat/SPI): 0.000146
    • LIPO(Sec/SPII): 0.000197
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MVLRKVIMQDLDQIIALENIGFSPEEAATREALKLRIEQIQETFIVAEKNDEVIGYINGPVIKERYISDDLFKNVSTNNSEGGYISVLGLVVAPNYQGQGIAGRLLNYFETLAKNHHRHGVTLTCRESLISFYEKYGYRNEGVSESCHGGIKWYNLVKNIKKDDEV

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]