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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS04605 [old locus tag: NWMN_0814 ]
  • pan locus tag?: SAUPAN003044000
  • symbol: NWMN_RS04605
  • pan gene symbol?:
  • synonym:
  • product: thioesterase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS04605 [old locus tag: NWMN_0814 ]
  • symbol: NWMN_RS04605
  • product: thioesterase
  • replicon: chromosome
  • strand: +
  • coordinates: 903144..903518
  • length: 375
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (903144..903518) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0814

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGACTCATTTATTAGAGACATTTGAGATGTCAATAGATCACCAGGAAGATGGTTTAGTT
    GTTATTTCTATGCCTGTTACTGATAAAGTAAAACAACCATTTGGATATTTACATGGTGGG
    GCTTCGATTGCTTTAGGTGAAACAGCATGTTCATTAGGATCTGCTAATTTAATTGATACA
    ACCAAATTTATTCCATTAGGTTTAGAGATGAATGCTAACCATATTCATTCTGCTAAAGAT
    GGTCGTGTTACTGCGACAGCTGAAATTATTCATCGAGGTAAGTCGACACATGTATGGGAT
    ATAAAAATTAAGAATGACAAAGAACAATTAATTACAGTTATGCGTGGTACAGTTGCTATT
    AAACCTTTAAAATAA
    60
    120
    180
    240
    300
    360
    375

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS04605 [old locus tag: NWMN_0814 ]
  • symbol: NWMN_RS04605
  • description: thioesterase
  • length: 124
  • theoretical pI: 7.23489
  • theoretical MW: 13544.6
  • GRAVY: -0.0669355

Function[edit | edit source]

  • TIGRFAM:
    uncharacterized domain 1 (TIGR00369; HMM-score: 99.9)
    and 1 more
    phenylacetic acid degradation protein PaaD (TIGR02286; HMM-score: 38.9)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    HotDog (CL0050) 4HBT; Thioesterase superfamily (PF03061; HMM-score: 53.7)
    and 3 more
    DUF4442; Domain of unknown function (DUF4442) (PF14539; HMM-score: 21.5)
    4HBT_3; Thioesterase-like superfamily (PF13622; HMM-score: 17.9)
    GlnB-like (CL0089) CutA1; CutA1 divalent ion tolerance protein (PF03091; HMM-score: 12.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007452
    • TAT(Tat/SPI): 0.002648
    • LIPO(Sec/SPII): 0.000704
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MTHLLETFEMSIDHQEDGLVVISMPVTDKVKQPFGYLHGGASIALGETACSLGSANLIDTTKFIPLGLEMNANHIHSAKDGRVTATAEIIHRGKSTHVWDIKIKNDKEQLITVMRGTVAIKPLK

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]