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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS06040 [old locus tag: NWMN_1069 ]
  • pan locus tag?: SAUPAN003402000
  • symbol: NWMN_RS06040
  • pan gene symbol?: efb
  • synonym:
  • product: fibrinogen-binding protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS06040 [old locus tag: NWMN_1069 ]
  • symbol: NWMN_RS06040
  • product: fibrinogen-binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1172925..1173422
  • length: 498
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (1172925..1173422) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAAAAATAAATTGATAGCAAAATCTTTATTAACATTAGCGGCAATAGGTATTACTACA
    ACTACAATTGCGTCAACAGCAGATGCGAGCGAAGGATACGGTCCAAGAGAAAAGAAACCA
    GTGAGTATTAATCACAATATCGTAGAGTACAATGATGGTACTTTTAAATATCAATCTAGA
    CCAAAATTTAACTCAACACCTAAATATATTAAATTCAAACATGACTATAATATTTTAGAA
    TTTAACGATGGTACATTCGAATATGGTGCACGTCCACAATTTAATAAACCAGCAGCGAAA
    ACTGATGCAACTATTAAAAAAGAACAAAAATTGATTCAAGCTCAAAATCTTGTGAGAGAA
    TTTGAAAAAACACATACTGTCAGTGCACACAGAAAAGCACAAAAGGCAGTCAACTTAGTT
    TCGTTTGAATACAAAGTGAAGAAAATGGTCTTACAAGAGCGAATTGATAATGTATTAAAA
    CAAGGATTAGTTAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    498

Protein[edit source | edit]

Protein Data Bank: 1EFB
Protein Data Bank: 3D5R
Protein Data Bank: 3D5S

General[edit source | edit]

  • locus tag: NWMN_RS06040 [old locus tag: NWMN_1069 ]
  • symbol: NWMN_RS06040
  • description: fibrinogen-binding protein
  • length: 165
  • theoretical pI: 10.4514
  • theoretical MW: 18764.5
  • GRAVY: -0.632121

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:
  • PFAM:
    no clan definedefb-c; Extracellular fibrinogen binding protein C terminal (PF12199; HMM-score: 130.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.02
    • Extracellular Score: 9.98
    • Internal Helix: 1
  • LocateP:
  • SignalP: Signal peptide length 30 aa
    • Ymax: 0.695
    • Ymax_pos: 30
    • Cmax: 0.614
    • Cmax_pos: 30
    • Smax: 0.936
    • Smax_pos: 14
    • Smean: 0.853
    • D: 0.756
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446714256 NCBI
  • RefSeq: WP_000791587 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MKNKLIAKSLLTLAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS06040 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]