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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS08810 [old locus tag: NWMN_1571 ]
  • pan locus tag?: SAUPAN004295000
  • symbol: NWMN_RS08810
  • pan gene symbol?:
  • synonym:
  • product: DNA mismatch repair protein MutT

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS08810 [old locus tag: NWMN_1571 ]
  • symbol: NWMN_RS08810
  • product: DNA mismatch repair protein MutT
  • replicon: chromosome
  • strand: -
  • coordinates: 1738498..1739106
  • length: 609
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (1738498..1739106) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1571

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTCTAAATTTGATGAACAAATCATTGTAGTACCTAGAGAAATTATTTTTAATAATGAA
    AAGAATACTTTCAATGGGTTTTTAAATAAGAATAAACCAGAAGGTCAAAATATTTTTGAT
    GCGCTAAGTCAATATGAAGTTAAGCGACGCGGCGATATGGAAGAGGATCCATCATATAAA
    CAACTCATTTCTTATTGTTTACTTGAAAATGAGCATGGCGAGATATTAGTGTATGAACGA
    TTATCTGGCGGTGGAGAAGCTCGATTGCATGGACAATCTTCAATAGGTGTAGGCGGTCAT
    ATGAATGATGTTCCAGGAGCAGAATCTATTAACGAAGTATTGAGAGTTAATGCACAGAGA
    GAATTAGAAGAAGAAGTAGGTTTAAGTGAGCAAGATTCACAAAATATGGAATATATCGGT
    TTTATTAATGACGATAATAATGAAGTGGGCAAGGTACATATTGGTGTTGTATTTAAAATC
    ACTGTAAGTACGAATGATGTAGAAGCTAAAGAAACAGATACTTTACGAATAAAATGGGTT
    GAAAAAGGCAACATAGAGTCATATGATGATTTCGAAACGTGGAGTGCATTAATCCTTCAA
    GATTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    609

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS08810 [old locus tag: NWMN_1571 ]
  • symbol: NWMN_RS08810
  • description: DNA mismatch repair protein MutT
  • length: 202
  • theoretical pI: 4.2014
  • theoretical MW: 22946.3
  • GRAVY: -0.579703

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair mutator mutT protein (TIGR00586; EC 3.6.1.-; HMM-score: 15.8)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    NUDIX (CL0261) NUDIX; NUDIX domain (PF00293; HMM-score: 32.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004186
    • TAT(Tat/SPI): 0.00024
    • LIPO(Sec/SPII): 0.000509
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MSKFDEQIIVVPREIIFNNEKNTFNGFLNKNKPEGQNIFDALSQYEVKRRGDMEEDPSYKQLISYCLLENEHGEILVYERLSGGGEARLHGQSSIGVGGHMNDVPGAESINEVLRVNAQRELEEEVGLSEQDSQNMEYIGFINDDNNEVGKVHIGVVFKITVSTNDVEAKETDTLRIKWVEKGNIESYDDFETWSALILQDL

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]