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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS09795 [old locus tag: NWMN_1738 ]
  • pan locus tag?: SAUPAN004777000
  • symbol: NWMN_RS09795
  • pan gene symbol?:
  • synonym:
  • product: DUF445 domain-containing protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS09795 [old locus tag: NWMN_1738 ]
  • symbol: NWMN_RS09795
  • product: DUF445 domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1939426..1940550
  • length: 1125
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (1939426..1940550) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGAATGCACTATTTATTATCATATTTATGATTGTAGTAGGGGCGATAATTGGTGGCATT
    ACTAATGTAATTGCAATTAGAATGCTGTTTCACCCCTTTAAACCATACTATATATTTAAA
    TTTAGAGTCCCATTTACACCAGGTTTAATACCGAAAAGACGCGAAGAAATTGCAACTAAA
    ATTGGCCAAGTGATTGAAGAGCATTTGCTTACAGAAACTTTAATTAATGAAAAATTGAAA
    AGCGAGCAATCACAGCAAGCAATAGAATCTATGATTCAACAGCAGTTACAAAAGTTGACG
    AAAGATCAATTGTCAATAAAACAAATTACTTCTCAAATCGATATTGATTTAGAACAAGTA
    TTACAAACTAATGGAAATCAATATATTGAATCACAATTGAATAATTATTATACAAAGCAT
    CAAAACCAAACAATAGCATCTTTATTGCCAAATCAACTTGTAACATTTTTAAATCAGCAT
    GTAGATAACGCAACAGACTTATTATGTGATCGTGCAAGGAATTATTTATCATCTGCAAAA
    GGCACACAAGATATTAATGATATGTTGGATACTTTTTTCAATGAGAAAGGTAAGTTAATT
    GGTATGTTGCAAATGTTTATGACAAAAGAGAGTATTGCAGATCGCATTCAACAAGAACTT
    ATACGTTTAACATCTCATCCTAAAGCAAGAACAATTGTGACATCGTTAATTACCAATGAA
    TATCAAACTTTTAAAGATAAACCATTGAATGAACTGTTAGATGCATCGCAGTTTAATGAA
    ATCGCTGAAAATCTATCAGTGTATGTAACAACATATGCAAGCAAACAAGCGAATAAGCCA
    GTGGTTACGTTAATGCCTCAATTCGTTGATTATTTAGAAGGTCAACTCTCTAGCAAATTA
    GCAAATTTAATCATTGAAAAATTATCGATTCACTTATCTACAATTATGAAAAAAGTGGAT
    TTACGAGGATTAATTGAAGAACAAATTAATACGTTTGACTTAGATTATATTGAAAAATTA
    ATTATAGAAATTGCTAACAAAGAACTAAAGTTGATTATGTCATTAGGTTTCATTTTAGGT
    GGTATTATTGGATTTTTCCAAGGTTTGGTTGCAATCTTTGTCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1125

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS09795 [old locus tag: NWMN_1738 ]
  • symbol: NWMN_RS09795
  • description: DUF445 domain-containing protein
  • length: 374
  • theoretical pI: 6.26855
  • theoretical MW: 42695.4
  • GRAVY: 0.0117647

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    conserved hypothetical protein (TIGR04540; HMM-score: 5.6)
    6-pyruvoyl tetrahydropterin synthase-related domain (TIGR03112; HMM-score: 4.9)
  • TheSEED:
  • PFAM:
    no clan definedDUF445; Protein of unknown function (DUF445) (PF04286; HMM-score: 252.7)
    HUP (CL0039) BshC; Bacillithiol biosynthesis BshC (PF10079; HMM-score: 16.3)
    Dim_A_B_barrel (CL0032) Cyclase_polyket; Polyketide synthesis cyclase (PF04673; HMM-score: 12.4)
    no clan definedMukF_C; MukF C-terminal domain (PF17193; HMM-score: 10.3)
    Nexin_C; Sorting nexin C terminal (PF08628; HMM-score: 9.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.148
    • Ymax_pos: 26
    • Cmax: 0.274
    • Cmax_pos: 26
    • Smax: 0.205
    • Smax_pos: 6
    • Smean: 0.126
    • D: 0.139
  • predicted transmembrane helices (TMHMM): 2

Accession numbers[edit source | edit]

  • GI: 446915271 NCBI
  • RefSeq: WP_000992527 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MNALFIIIFMIVVGAIIGGITNVIAIRMLFHPFKPYYIFKFRVPFTPGLIPKRREEIATKIGQVIEEHLLTETLINEKLKSEQSQQAIESMIQQQLQKLTKDQLSIKQITSQIDIDLEQVLQTNGNQYIESQLNNYYTKHQNQTIASLLPNQLVTFLNQHVDNATDLLCDRARNYLSSAKGTQDINDMLDTFFNEKGKLIGMLQMFMTKESIADRIQQELIRLTSHPKARTIVTSLITNEYQTFKDKPLNELLDASQFNEIAENLSVYVTTYASKQANKPVVTLMPQFVDYLEGQLSSKLANLIIEKLSIHLSTIMKKVDLRGLIEEQINTFDLDYIEKLIIEIANKELKLIMSLGFILGGIIGFFQGLVAIFV

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS09795 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]