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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS10410 [old locus tag: NWMN_1812 ]
  • pan locus tag?: SAUPAN001766000
  • symbol: NWMN_RS10410
  • pan gene symbol?:
  • synonym:
  • product: DNA-binding protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS10410 [old locus tag: NWMN_1812 ]
  • symbol: NWMN_RS10410
  • product: DNA-binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2020253..2020891
  • length: 639
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_009641 (2020253..2020891) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1812

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGGCTTTCAAAAATTCCATAAAAGAAATCAGATTGAACAATAGATTGTCTAAAGTTGAG
    ATGGCTAAAAAATTAGATGTTTCCGAAGGTACTATAAGAATGTGGGAAAGTGGAAGAACT
    GAACCTAGAATGGGTATGGTCGAAAAAATTTCAAGTTTGTTCAATGTTTCTAAAGGTTAT
    CTCTTAGGAGAAATTGAAGAAATTGTTTTACCAGAATTTGATAGCGAAATCGAGGTTCCA
    TATTTCGGTAAAGTTTCTGCTGGAAATTTCGAGGAAGTTGCAATTGATAATGAAAAATTA
    AAAGTTCCACCATTTGCTTTTAACGGTCGTAAACCTAGCGAATGTATAGCACTAAAAATA
    AACGGAGATAGCATGAATAAAATACTCGCTAACGGTTCTTATATAATTGTCCATGATTAT
    AGAAAGTCTTGTGATCATAAACTTAACAGCAATGACATCCTTGTATTACGTCTAGGTGGT
    GAATATACAGTTAAGCGTGTGAGACGTACTGAAACAAAACTACATTTAGACCCAGCAAGC
    TATTCAGATGAATTTAAAACTAATTCTTACGATTTAGATTCTATTGATGAAATCGAAGTG
    ATAGGCAAAGTTATTTATAACTATCGTATTTTTGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    639

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS10410 [old locus tag: NWMN_1812 ]
  • symbol: NWMN_RS10410
  • description: DNA-binding protein
  • length: 212
  • theoretical pI: 5.8325
  • theoretical MW: 24241.6
  • GRAVY: -0.39717

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair repressor LexA (TIGR00498; EC 3.4.21.88; HMM-score: 40.9)
    Signal transduction Regulatory functions DNA interactions repressor LexA (TIGR00498; EC 3.4.21.88; HMM-score: 40.9)
    and 6 more
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 22.8)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking signal peptidase I (TIGR02227; EC 3.4.21.89; HMM-score: 20.4)
    Hypothetical proteins Conserved TIGR00270 family protein (TIGR00270; HMM-score: 19.7)
    putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 18.9)
    Cellular processes Cellular processes Detoxification nickel-type superoxide dismutase maturation protease (TIGR02754; EC 3.4.21.-; HMM-score: 13.1)
    Genetic information processing Protein fate Protein modification and repair nickel-type superoxide dismutase maturation protease (TIGR02754; EC 3.4.21.-; HMM-score: 13.1)
  • TheSEED:
  • PFAM:
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 49.2)
    and 8 more
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 35.9)
    Peptidase_SF (CL0299) Peptidase_S24; Peptidase S24-like (PF00717; HMM-score: 34.9)
    HTH (CL0123) HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 26.4)
    YdaS_antitoxin; Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT (PF15943; HMM-score: 15)
    HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 14.2)
    Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 12.8)
    MerR; MerR family regulatory protein (PF00376; HMM-score: 12.5)
    HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 12.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005335
    • TAT(Tat/SPI): 0.000248
    • LIPO(Sec/SPII): 0.000412
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MAFKNSIKEIRLNNRLSKVEMAKKLDVSEGTIRMWESGRTEPRMGMVEKISSLFNVSKGYLLGEIEEIVLPEFDSEIEVPYFGKVSAGNFEEVAIDNEKLKVPPFAFNGRKPSECIALKINGDSMNKILANGSYIIVHDYRKSCDHKLNSNDILVLRLGGEYTVKRVRRTETKLHLDPASYSDEFKTNSYDLDSIDEIEVIGKVIYNYRIFD

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]