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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS10425 [old locus tag: NWMN_1814 ]
  • pan locus tag?: SAUPAN004876000
  • symbol: NWMN_RS10425
  • pan gene symbol?: int2
  • synonym:
  • product: site-specific integrase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS10425 [old locus tag: NWMN_1814 ]
  • symbol: NWMN_RS10425
  • product: site-specific integrase
  • replicon: chromosome
  • strand: +
  • coordinates: 2022127..2023173
  • length: 1047
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (2022127..2023173) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1814

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGCCAGTATATAAGGATGATAATACAGGTAAATGGTATTTTTCCATTAGATATAAAGAT
    GTATACGGTAATAACAAACGAAAAATGAAGCGTGGGTTTGAACGTAAGAAAGATGCCAAA
    CTAGCTGAAAGCGAATTTATACAAAATGTTAAATATGGATACTCGGACAATCAACCCTTT
    GAATATATATTTTTTAATCGTTTAAAAAATGAAAATCTTTCTGCACGCTCAATAGAAAAG
    CGAACTACAGAATATAATACTCACATAAAAGAAAGGTTCGGAAATATCCCTATTGGCAAA
    ATCACTACTACGCAATGTACTGCTTTCAGGAATTATTTGTTAAACGATGCAGGTCTTTCT
    GTTGGCTATGCACGATCTGTGTGGGCAGGTTTTAAAGCAGTTATCAATTACGCCAAAAAG
    CATTACAAGCTCTTATACGACCCCACATTATCGGTAACTCCTATTCCCAGAACAAAACCA
    CAAGCTAAATTTATCACTCGTGAAGAATTTGATGAAAAAGTAGAACAAATCACAAACGAT
    ACTTCTCGTCAGCTAACTAAACTGTTATTTTATTCTGGTCTTAGAATAGGCGAAGCTTTA
    GCTTTGCAGTGGAAAGATTACGATAAAATAAAAGGCGAAATTGACGTAAATAAGAAAATC
    AATTTAAGTAATAGAGAAATTGAATATAATCTAAAAAAAGAAAGTTCTAAAGGGATAATA
    CCTGTACCAAAATTAATTAGAGAGATGCTTAAAAACATGTATAATGAATCTTCTAAAAGA
    TATAAATATTTTGACGAAAACTATTTTATATTCGGGGGGTTAGAACCTATTAGATACGTT
    ACCTATTCGTATCATTTTAAATCTGTATTCCCGAATCTAAAAATACACCATTTAAGACAC
    TCGTACGCAAGCTATTTAATTAATAATGGTGTAGATATGTATTTATTAATGGAATTAATG
    AGGCACTCTAACATTACAGAAACAATTCAAACGTACTCTCATTTATATACTGATAAAAAA
    CATCAAGCTATGAACATATTTGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1047

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS10425 [old locus tag: NWMN_1814 ]
  • symbol: NWMN_RS10425
  • description: site-specific integrase
  • length: 348
  • theoretical pI: 9.97772
  • theoretical MW: 41333
  • GRAVY: -0.712356

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerC (TIGR02224; HMM-score: 53)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerD (TIGR02225; HMM-score: 46.6)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair integron integrase (TIGR02249; HMM-score: 43.6)
    Genetic information processing Mobile and extrachromosomal element functions Other integron integrase (TIGR02249; HMM-score: 43.6)
  • TheSEED: data available for NCTC8325
  • PFAM:
    DNA-mend (CL0382) Phage_integrase; Phage integrase family (PF00589; HMM-score: 70.4)
    and 4 more
    MBD-like (CL0081) Arm-DNA-bind_4; Arm DNA-binding domain (PF14657; HMM-score: 45.8)
    l-integrase_N (CL0469) Phage_int_SAM_3; Phage integrase, N-terminal SAM-like domain (PF14659; HMM-score: 30.6)
    Phage_int_SAM_5; Phage integrase SAM-like domain (PF13102; HMM-score: 26.6)
    no clan defined DUF5126; Domain of unknown function (DUF5126) (PF17166; HMM-score: 9.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.014878
    • TAT(Tat/SPI): 0.00072
    • LIPO(Sec/SPII): 0.004127
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MPVYKDDNTGKWYFSIRYKDVYGNNKRKMKRGFERKKDAKLAESEFIQNVKYGYSDNQPFEYIFFNRLKNENLSARSIEKRTTEYNTHIKERFGNIPIGKITTTQCTAFRNYLLNDAGLSVGYARSVWAGFKAVINYAKKHYKLLYDPTLSVTPIPRTKPQAKFITREEFDEKVEQITNDTSRQLTKLLFYSGLRIGEALALQWKDYDKIKGEIDVNKKINLSNREIEYNLKKESSKGIIPVPKLIREMLKNMYNESSKRYKYFDENYFIFGGLEPIRYVTYSYHFKSVFPNLKIHHLRHSYASYLINNGVDMYLLMELMRHSNITETIQTYSHLYTDKKHQAMNIFD

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]