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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS11465 [old locus tag: NWMN_1982 ]
  • pan locus tag?: SAUPAN005349000
  • symbol: NWMN_RS11465
  • pan gene symbol?: kdpA
  • synonym:
  • product: potassium-transporting ATPase A chain

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS11465 [old locus tag: NWMN_1982 ]
  • symbol: NWMN_RS11465
  • product: potassium-transporting ATPase A chain
  • replicon: chromosome
  • strand: -
  • coordinates: 2200157..2201833
  • length: 1677
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (2200157..2201833) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
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    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGGAAATAATTTTGTTTCTAACAATGATGGTTATGATTACGTATGTTTTTAGTGGATAT
    CTATATCGCGTAGCATTGGTGCAATCGTCAAGAGTAGATTTAATATTTACTAGATTTGAA
    AATATGTGTTTTAAAATTATCGGCACAGATTTAGAACACATGTCAGCTAAAACATATGTC
    AAACATTTTCTGGCATTTAATGGATTTATGGGGTTTATAACATTTGTATTGCTAATAGTT
    CAGCAATGGCTTTTTTTAAATCCAAATCATAATTTAAACCAATCGATAGATTTAGCGTTT
    AATACAGCAATATCTTTTTTAACAAATAGTAATTTACAACACTATAACGGTGAATCAGAT
    GTGACATATTTAACGCAAATGATTGTAATGACATATTTAATGTTTACATCTAGTGCATCA
    GGTTACGCCGTTTGTATAGCGATGTTGAGACGTTTAACTGGATTAACTAATATCATTGGT
    AATTTTTATCAAGATATTGTTCGGTTTATTGTCCGAGTACTTTTACCATTATCATGTTTA
    ATTAGTATTTTATTGATGACTCAAGGTGTACCACAAACGTTGCATGCTAATTTAATGATT
    CGGACTTTAAGCGGACATATTCAACATATTGCATTTGGACCTATTGCATCACTTGAATCA
    ATAAAACATCTTGGTACGAATGGTGGAGGATTTTTAGCAGGAAATTCTGCAACACCTTTT
    GAAAATCCAAATATTTGGAGCAATTTTATAGAAATGGGCAGTATGATGTTACTTCCTATG
    TCAATGTTGTTCTTATTTGGTCGCATGTTAAGTAGACATGGTAAACGAGTACATCGTCAT
    GCGTTGATATTATTTGTCGCAATGTTTTTCATTTTTATAGCAATTCTTACATTAACTATG
    TGGAGTGAGTATCGTGGTAATCCAATACTAGCGAATTTAGGCATTTATGGACCGAATATG
    GAAGGTAAAGAGGTACGGTTTGGAGCAGGTTTGTCAGCACTATTTACAGTTATTACGACG
    GCATTTACAACGGGTTCTGTTAATAACATGCATGATAGCTTAACGCCTATAGGTGGATTA
    GGACCAATGGTATTAATGATGCTAAATGTTGTATTTGGTGGCGAAGGCGTAGGACTCATG
    AATTTATTGATATTTGTCTTACTGACGGTGTTTATATGCAGTTTGATGGTTGGTAAAACA
    CCAGAATATTTAAATATGCCAATTGGCGCCCGTGAAATGAAATGTATTGTCTTAGTCTTT
    CTCATACACCCAATTTTAATTTTAGTATTTTCAGCACTTGCTTTTATGATTCCTGGAGCA
    AGTGAAAGTATAACGAATCCGTCTTTTCATGGTATTTCACAAGTTATGTATGAAATGACA
    TCAGCTGCTGCGAACAATGGATCAGGGTTTGAAGGACTGAAAGATGATACAACATTCTGG
    AATATCTCTACAGGAATCATTATGTTGCTTTCTCGTTATATACCAATTATTTTGCAATTA
    ATGATTGCATCAAGTTTAGTGAATAAAAAATCATACCATCAAGATAAATATACAATAGCG
    ATTGATAAACCTTATTTTGGCGTATCACTAATCGTATTTATCGTTTTACTAAGTGGTTTG
    ACATTTATTCCAGTACTATTACTTGGTCCTATTGGTGAATTTTTAACTTTAAAATAA
    60
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    360
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    720
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    840
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    1020
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    1140
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    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1677

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS11465 [old locus tag: NWMN_1982 ]
  • symbol: NWMN_RS11465
  • description: potassium-transporting ATPase A chain
  • length: 558
  • theoretical pI: 8.44178
  • theoretical MW: 62025.5
  • GRAVY: 0.688351

Function[edit source | edit]

  • reaction:
    EC 3.6.3.12?  ExPASy
    Potassium-transporting ATPaseATP + H2O + K+(Out) = ADP + phosphate + K+(In)
  • TIGRFAM:
    MetabolismTransport and binding proteinsCations and iron carrying compoundsK+-transporting ATPase, A subunit (TIGR00680; EC 3.6.3.12; HMM-score: 580.7)
  • TheSEED:
  • PFAM:
    Ion_channel (CL0030) KdpA; Potassium-transporting ATPase A subunit (PF03814; HMM-score: 706.7)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.118
    • Ymax_pos: 11
    • Cmax: 0.12
    • Cmax_pos: 57
    • Smax: 0.218
    • Smax_pos: 1
    • Smean: 0.122
    • D: 0.12
  • predicted transmembrane helices (TMHMM): 12

Accession numbers[edit source | edit]

  • GI: 446324801 NCBI
  • RefSeq: WP_000402656 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MEIILFLTMMVMITYVFSGYLYRVALVQSSRVDLIFTRFENMCFKIIGTDLEHMSAKTYVKHFLAFNGFMGFITFVLLIVQQWLFLNPNHNLNQSIDLAFNTAISFLTNSNLQHYNGESDVTYLTQMIVMTYLMFTSSASGYAVCIAMLRRLTGLTNIIGNFYQDIVRFIVRVLLPLSCLISILLMTQGVPQTLHANLMIRTLSGHIQHIAFGPIASLESIKHLGTNGGGFLAGNSATPFENPNIWSNFIEMGSMMLLPMSMLFLFGRMLSRHGKRVHRHALILFVAMFFIFIAILTLTMWSEYRGNPILANLGIYGPNMEGKEVRFGAGLSALFTVITTAFTTGSVNNMHDSLTPIGGLGPMVLMMLNVVFGGEGVGLMNLLIFVLLTVFICSLMVGKTPEYLNMPIGAREMKCIVLVFLIHPILILVFSALAFMIPGASESITNPSFHGISQVMYEMTSAAANNGSGFEGLKDDTTFWNISTGIIMLLSRYIPIILQLMIASSLVNKKSYHQDKYTIAIDKPYFGVSLIVFIVLLSGLTFIPVLLLGPIGEFLTLK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS11465 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]