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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0191 [new locus tag: SA_RS01135 ]
  • pan locus tag?: SAUPAN001044000
  • symbol: SA0191
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA0191 [new locus tag: SA_RS01135 ]
  • symbol: SA0191
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 226088..227200
  • length: 1113
  • essential: no DEG

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    TTGAGGCGTAAAAGGAAATGGCTAATTGTTATTTGTGTATTATTAGTATTGATTACGATA
    TCACAAATTTTGAAACATTTTAACTATGGAACTGAGAGTAAAGAAGCATACAATACATAT
    ACGGTTGAAAAAGAAAGACAATTAGATTTACAAGGTAAGGCATATCCACGTGAAGTTAAA
    ACATATTATAAAAATAATCAGGTTGGAACATATTTGGGTGTGCAAGTAGCGGACGGGCAA
    ACAGTCAAAAAAGGAGACATGTTAATTAATTATAAAATAAATAGTAATAAACGACAGCAA
    CTTGTTGATAAGATAAATGATACTCAACATATTATTACAGAAGTTTATTTAAACATTACT
    AAAGGTTTAAACAATCGAGAGATACAGAAGAAGTTAATTGAATATAAGCAGACATTATAT
    GAAGCTCAACAGCAATTGTATCAGTATGATAGTCAAAATAGGGATAGTATGTATGCATCA
    TTTGATGGCAAGATTATGATCAAGAATATAGATAATGACAGTGATAATCAACCTATACTG
    TATCTCATTTCAAAGGAGTCTCATATTAAAACGTCTGTTACGGAGTTTGATTTAAACAAA
    GTCAAAAAAGGAGACAAAGTTAACTTAAGTATTACGAGTACGGGTAAAACAGGAGCGGGG
    ATTATAAAACAAATCTCTGAGTTGCCTATTAGTTATGAAGAGAATTTAAGTCTTCACGAA
    AATGATGCCCTGCATTTACCAGAAAGTAACAACGATGGGGAATTAGCAAATTCAAAATCG
    ATTTCGGCATCTCCAATATTTAAGAGTAATAACAACTCTGAATTATCAAAGTATGGAGTT
    ATAATTGATGATCTTAGTCTACCAATACGTGCAGGTTATTCGTTGGAAATTAAAGTCCCA
    TTAAATGCGATTAAAATACCTAAATCAGTATTAACAAAAGGCAATAATGTTTTTATTGTT
    AATAAAAATAGTATTGTGGAAAAACGGAATATTCGTATAAAAAGAATCAATGGTGACATT
    ATTGTAGAAAAGGGGTTAAAACCTGGAGACAAGTTAATTAAACAACCTAAAAGTACAATG
    AATGATGGTGATAAGGTTGAGATTTCGTCATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1113

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA0191 [new locus tag: SA_RS01135 ]
  • symbol: SA0191
  • description: hypothetical protein
  • length: 370
  • theoretical pI: 9.80936
  • theoretical MW: 42045.8
  • GRAVY: -0.559459

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Unknown substrate efflux transporter, RND family, MFP subunit (TIGR01730; HMM-score: 53.8)
    and 2 more
    Metabolism Transport and binding proteins Other membrane fusion protein cluster 2 protein (TIGR00999; HMM-score: 26.9)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion membrane fusion protein, HlyD family (TIGR01843; HMM-score: 9.8)
  • TheSEED  :
    • ABC transporter, RND-adapter-like protein SERP0014
  • PFAM:
    TPR (CL0020) Tcf25; Transcriptional repressor TCF25 (PF04910; HMM-score: 13.2)
    Hybrid (CL0105) Biotin_lipoyl_2; Biotin-lipoyl like (PF13533; HMM-score: 13)
    no clan defined Myosin-VI_CBD; Myosin VI cargo binding domain (PF16521; HMM-score: 12.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 4.6
    • Cellwall Score: 2.48
    • Extracellular Score: 2.92
    • Internal Helix: 1
  • LocateP: N-terminally anchored (No CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0.5
    • N-terminally Anchored Score: 4
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: Signal peptide SP(Sec/SPI) length 33 aa
    • SP(Sec/SPI): 0.635664
    • TAT(Tat/SPI): 0.001514
    • LIPO(Sec/SPII): 0.043977
    • Cleavage Site: CS pos: 33-34. TES-KE. Pr: 0.2258
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MRRKRKWLIVICVLLVLITISQILKHFNYGTESKEAYNTYTVEKERQLDLQGKAYPREVKTYYKNNQVGTYLGVQVADGQTVKKGDMLINYKINSNKRQQLVDKINDTQHIITEVYLNITKGLNNREIQKKLIEYKQTLYEAQQQLYQYDSQNRDSMYASFDGKIMIKNIDNDSDNQPILYLISKESHIKTSVTEFDLNKVKKGDKVNLSITSTGKTGAGIIKQISELPISYEENLSLHENDALHLPESNNDGELANSKSISASPIFKSNNNSELSKYGVIIDDLSLPIRAGYSLEIKVPLNAIKIPKSVLTKGNNVFIVNKNSIVEKRNIRIKRINGDIIVEKGLKPGDKLIKQPKSTMNDGDKVEISS

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]