NCBI: 26-AUG-2013

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA0425 [new locus tag: SA_RS02420 ]
• pan locus tag^?: SAUPAN002181000
• symbol: SA0425
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Gene

⊟General

• type: CDS
• locus tag: SA0425 [new locus tag: SA_RS02420 ]
• symbol: SA0425
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 486548..486943
• length: 396
• essential: no DEG other strains

⊟Accession numbers

• Gene ID: 1123210 NCBI
• RefSeq: NP_373677 NCBI
• MicrobesOnline: 102703 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  ATGATTAAATGTGTCTGTTTAGTTGAAGAAACAGCTGATAAAATATTGCTTGTTCAAGTA
  AGGAATCGCGAAAAGTATTATTTCCCAGGTGGTAAAATAGAAGAAGGAGAATCACAAGTA
  CACGCGCTGTTAAGAGAAGTAAAAGAAGAATTAAATTTAACATTAACAATGGATGAAATT
  GAATATATCGGGACAATTGTAGGTCCTGCATATCCACAACAGGATATGTTAACTGAGTTA
  AATGGATTTCGCGCATTAACCAAAATCGATTGGGAAAACGTAACTATCAATAATGAAATT
  ACGGATATACGCTGGATTGATAAAGATAATGATGCGTTGATTGCGCCTGCTGTCAAAGTT
  TGGATTGAAACGTATGGTGGTAAACATGACAAATAA
  60
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  396
  

⊟Protein

⊟General

• locus tag: SA0425 [new locus tag: SA_RS02420 ]
• symbol: SA0425
• description: hypothetical protein
• length: 131
• theoretical pI: 4.42501
• theoretical MW: 15067.2
• GRAVY: -0.315267

⊟Function

• reaction:
• TIGRFAM:
  Genetic information processingDNA metabolismDNA replication, recombination, and repairnucleoside triphosphatase YtkD (TIGR02705; EC 3.6.1.-; HMM-score: 32.4)
  Genetic information processingDNA metabolismDNA replication, recombination, and repairmutator mutT protein (TIGR00586; EC 3.6.1.-; HMM-score: 30.5)
  MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersOtherisopentenyl-diphosphate delta-isomerase (TIGR02150; EC 5.3.3.2; HMM-score: 12.4)
• TheSEED:  
  FIG01107849: hypothetical protein 
• PFAM:
  NUDIX (CL0261) NUDIX; NUDIX domain (PF00293; HMM-score: 44.1)
  NUDIX_2; Nucleotide hydrolase (PF13869; HMM-score: 20.7)

⊟Structure, modifications & interactions

• domains:
• modifications:
• cofactors:
• effectors:
• protein partners:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular Possibility: 1
  • Signal Peptide Possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • Ymax: 0.116
  • Ymax_pos: 11
  • Cmax: 0.109
  • Cmax_pos: 25
  • Smax: 0.172
  • Smax_pos: 20
  • Smean: 0.136
  • D: 0.124
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 15926144 NCBI
• RefSeq: NP_373677 NCBI
• UniProt: A0A0H3JJW2 UniProt

⊟Protein sequence

• MIKCVCLVEETADKILLVQVRNREKYYFPGGKIEEGESQVHALLREVKEELNLTLTMDEIEYIGTIVGPAYPQQDMLTELNGFRALTKIDWENVTINNEITDIRWIDKDNDALIAPAVKVWIETYGGKHDK

⊟Experimental data

• experimentally validated: no data available

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SA0425 > SA0426

⊟Regulation

• sigma factor:
• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: data available for COL

⊟Protein stability

• half-life: no data available

⊟Other Information

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