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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1296 [new locus tag: SA_RS07335 ]
  • pan locus tag?: SAUPAN003923000
  • symbol: SA1296
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA1296 [new locus tag: SA_RS07335 ]
  • symbol: SA1296
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1501867..1503111
  • length: 1245
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGAAGATATCTATAAATTAATAGACGATATCAATCTACAAAAACTAGAAAATTTAGAC
    TCTCGTGTTAATGAAGCAATAACTACTGACAACGATGACGCATTATTTATTCTAGGAGAG
    ACACTTTACAATTTTGGATTAATGCCACAAGGTTTGGAAGTATTCCGCGTGTTATATCAC
    AAATATCCAGACGAAAGTGAATTGCTGATTTATTTTATTGAAGGTTTAATGTCTGAAAAT
    CAAACTGACGAAGCGTTAGAATATTTAAGTTATGTTGAACCATCACCTGAAAAGTTGATG
    TTAGAAGCAGATTTATATCAACAAATTAATATGATGGAAGTTGCTATTGATAAATTACAA
    GAAGCACTTGAACTAGAGCCAAATGATCCAATAATCCATTTTGCATTGGCTGAAATGTTA
    TATTATGATGGTCAATATTTACGTGCTACCTCTGAATACGAAACCGTTTTAGAAACTGGT
    GAATATCAAGTTAATGGTGTAAACTTATTCTCTCGTATGGCAGATTGTAGTTTACAAAGT
    GGTAACTATAGTGATGCGATTCGCTTATACGATGAAATTAATGAAGATGAAATGACTTCA
    GAAGATTATCTCAAAAAAGCCATTTCTTACGATAAAAATGACATCACTCAAGAAGCAATT
    AAAATAATGACTACATTACTTTCTAAAGATCCTGATTATATTCAAGGCTACTTGTATTTA
    CAATCATTATATGAAAATGAAAAAAATTATCCAGATGCCATTGAGACGGGTAAAGAAGGA
    TTACGACTAAGTCAATTTTATAAAGAGTTAATGTATACAACTGGATGTTTGGAAATAGAA
    CACGGCGATGCTAATGAAGGTGTATTATTGTTAAAACAAGCATTAGAGGTTGATAATGCT
    TACCAAGAACCTTTATTGATTTTAAGCGATTTATATCGTAATGAAGAAGATTATGAAGCA
    ATCATTGAATTATTAACATATGTAGATGAAGAAGATTTGGATCCTACATTCATGTGGCAT
    TTAGCGTTCGCCTATGGTCAAGAAGAGCGAGATAAAGAAGCTCAACATTTCTTTGAATTA
    GCATATCCAACGATGAAAACAAATATTGATTTTATGAGTGATTATTATTTCTATTTAATT
    GAAATTGGTCAAAAGGAACAAGCAATTACTATTTTAAATCAATTGTTGGAACTAGAGCCA
    AGTAACGAAAATTGGCATGACGAATTATCAAGATTGCAATCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1245

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA1296 [new locus tag: SA_RS07335 ]
  • symbol: SA1296
  • description: hypothetical protein
  • length: 414
  • theoretical pI: 3.78508
  • theoretical MW: 48422.7
  • GRAVY: -0.439855

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    putative PEP-CTERM system TPR-repeat lipoprotein (TIGR02917; HMM-score: 73)
    type IV pilus biogenesis/stability protein PilW (TIGR02521; HMM-score: 45.4)
    type III secretion low calcium response chaperone LcrH/SycD (TIGR02552; HMM-score: 34.6)
    tol-pal system protein YbgF (TIGR02795; HMM-score: 30.2)
    poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA (TIGR03939; HMM-score: 21.1)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesmitochondrial precursor proteins import receptor (TIGR00990; HMM-score: 20.5)
    Unknown functionGeneralheme biosynthesis-associated TPR protein (TIGR00540; HMM-score: 19)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingouter membrane assembly lipoprotein YfiO (TIGR03302; HMM-score: 17.3)
    pentatricopeptide repeat domain (TIGR00756; HMM-score: 13.2)
  • TheSEED:  
    CBSS-393130.3.peg.129 TPR-repeat-containing protein, putative component of Menaquinone-cytochrome C reductase 
  • PFAM:
    TPR (CL0020) TPR_19; Tetratricopeptide repeat (PF14559; HMM-score: 79.2)
    TPR_2; Tetratricopeptide repeat (PF07719; HMM-score: 63.7)
    TPR_16; Tetratricopeptide repeat (PF13432; HMM-score: 49.3)
    TPR_6; Tetratricopeptide repeat (PF13174; HMM-score: 43)
    TPR_14; Tetratricopeptide repeat (PF13428; HMM-score: 40.7)
    TPR_7; Tetratricopeptide repeat (PF13176; HMM-score: 35)
    TPR_11; TPR repeat (PF13414; HMM-score: 33)
    TPR_15; Tetratricopeptide repeat (PF13429; HMM-score: 30.7)
    ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3 (PF12895; HMM-score: 29.5)
    TPR_12; Tetratricopeptide repeat (PF13424; HMM-score: 27.7)
    TPR_8; Tetratricopeptide repeat (PF13181; HMM-score: 25.6)
    BTAD; Bacterial transcriptional activator domain (PF03704; HMM-score: 23.4)
    TPR_20; Tetratricopeptide repeat (PF14561; HMM-score: 21.7)
    TPR_17; Tetratricopeptide repeat (PF13431; HMM-score: 20.5)
    TPR_9; Tetratricopeptide repeat (PF13371; HMM-score: 20.3)
    TPR_1; Tetratricopeptide repeat (PF00515; HMM-score: 17.8)
    SGNH_hydrolase (CL0264) DUF4886; Domain of unknown function (DUF4886) (PF16227; HMM-score: 15.9)
    TPR (CL0020) SNAP; Soluble NSF attachment protein, SNAP (PF14938; HMM-score: 15)
    no clan definedMIT; MIT (microtubule interacting and transport) domain (PF04212; HMM-score: 14.8)
    TPR (CL0020) PPR; PPR repeat (PF01535; HMM-score: 13.5)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.094
    • Ymax_pos: 27
    • Cmax: 0.108
    • Cmax_pos: 27
    • Smax: 0.108
    • Smax_pos: 24
    • Smean: 0.063
    • D: 0.081
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MEDIYKLIDDINLQKLENLDSRVNEAITTDNDDALFILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLSYVEPSPEKLMLEADLYQQINMMEVAIDKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETGEYQVNGVNLFSRMADCSLQSGNYSDAIRLYDEINEDEMTSEDYLKKAISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIEHGDANEGVLLLKQALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEEDLDPTFMWHLAFAYGQEERDKEAQHFFELAYPTMKTNIDFMSDYYFYLIEIGQKEQAITILNQLLELEPSNENWHDELSRLQS

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator: CodY
    CodY (TF) important in Amino acid metabolismRegPrecise

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]