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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1388 [new locus tag: SA_RS07850 ]
  • pan locus tag?: SAUPAN004140000
  • symbol: SA1388
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA1388 [new locus tag: SA_RS07850 ]
  • symbol: SA1388
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1593470..1594570
  • length: 1101
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGAAAATAGCTGATTTAATGACATTGTTAGATCATCATGTGCCATTTAGTACTGCTGAA
    TCTTGGGATAATGTAGGATTGTTAATAGGTGATGGAGATGTTGAAGTTACTGGTGTTTTA
    ACAGCATTAGACTGTACGTTGGAAGTAGTAAATGAAGCAATCGAAAAAGGTTATAATACT
    ATTATTAGTCATCATCCTCTAATCTTTAAAGGCGTAACATCATTAAAAGCTAATGGTTAT
    GGTTTGATCATTAGAAAACTAATTCAACATGACATTAATTTAATAGCGATGCATACAAAT
    TTAGATGTAAATCCGTATGGTGTCAATATGATGTTGGCGAAGGCGATGGGTTTGAAGAAC
    ATTTCAATAATAAATAATCAACAAGATGTATACTATAAAGTTCAAACATATATACCTAAG
    GATAATGTTGGACCATTTAAAGATAAGCTTAGTGAAAATGGATTAGCGCAAGAAGGTAAT
    TATGAATATTGTTTCTTTGAAAGTGAAGGAAGAGGGCAATTCAAACCAGTTGGTGAAGCT
    AATCCAACAATAGGACAAATTGATAAAATTGAAGATGTAGATGAAGTTAAAATTGAATTT
    ATGATAGATGCATATCAAAAGTCAAGGGCTGAGCAATTAATTAAACAATACCATCCATAT
    GAAACACCGGTATTTGATTTTATTGAGATAAAACAAACATCCCTTTATGGACTTGGCGTT
    ATGGCAGAAGTGGATAATCAAATGACATTGGAAGATTTCGCAGCTGATATTAAATCTAAA
    TTAAATATCCCAAGTGTCCGTTTTGTTGGTGAGTCTAATCAGAAAATTAAACGTATTGCA
    ATTATTGGTGGTTCAGGTATTGGATATGAATATCAAGCTGTCCAACAAGGCGCAGATGTC
    TTTGTTACAGGTGATATTAAACATCATGATGCCTTAGATGCTAAAATTCATGGTGTGAAT
    TTAATTGATATTAATCATTACAGCGAATATGTGATGAAAGAAGGTTTAAAAACGTTACTA
    ATGAATTGGTTCAATATAGAAAAAATAAATATAGATGTTGAAGCATCTACAATTAATACA
    GATCCATTTCAATATATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1101

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA1388 [new locus tag: SA_RS07850 ]
  • symbol: SA1388
  • description: hypothetical protein
  • length: 366
  • theoretical pI: 4.66964
  • theoretical MW: 41074.6
  • GRAVY: -0.162568

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Unknown functionGeneraldinuclear metal center protein, YbgI/SA1388 family (TIGR00486; HMM-score: 234)
  • TheSEED:  
    EC699-706 Bsu YqfO NIF3/CutA domain 
    EC699-706 GTP cyclohydrolase 1 type 2 homolog YbgI 
  • PFAM:
    no clan definedNIF3; NIF3 (NGG1p interacting factor 3) (PF01784; HMM-score: 270.6)
    GlnB-like (CL0089) CutA1; CutA1 divalent ion tolerance protein (PF03091; HMM-score: 15.7)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.19
    • Ymax_pos: 22
    • Cmax: 0.218
    • Cmax_pos: 22
    • Smax: 0.213
    • Smax_pos: 10
    • Smean: 0.157
    • D: 0.177
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKIADLMTLLDHHVPFSTAESWDNVGLLIGDGDVEVTGVLTALDCTLEVVNEAIEKGYNTIISHHPLIFKGVTSLKANGYGLIIRKLIQHDINLIAMHTNLDVNPYGVNMMLAKAMGLKNISIINNQQDVYYKVQTYIPKDNVGPFKDKLSENGLAQEGNYEYCFFESEGRGQFKPVGEANPTIGQIDKIEDVDEVKIEFMIDAYQKSRAEQLIKQYHPYETPVFDFIEIKQTSLYGLGVMAEVDNQMTLEDFAADIKSKLNIPSVRFVGESNQKIKRIAIIGGSGIGYEYQAVQQGADVFVTGDIKHHDALDAKIHGVNLIDINHYSEYVMKEGLKTLLMNWFNIEKINIDVEASTINTDPFQYI

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]

Kumar Singh Saikatendu, Xuejun Zhang, Lisa Kinch, Matthew Leybourne, Nick V Grishin, Hong Zhang
Structure of a conserved hypothetical protein SA1388 from S. aureus reveals a capped hexameric toroid with two PII domain lids and a dinuclear metal center.
BMC Struct. Biol.: 2006, 6;27
[PubMed:17187687] [WorldCat.org] [DOI] (I e)