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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1556 [new locus tag: SA_RS08775 ]
  • pan locus tag?: SAUPAN004399000
  • symbol: acuC
  • pan gene symbol?: acuC
  • synonym:
  • product: acetoin utilization protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA1556 [new locus tag: SA_RS08775 ]
  • symbol: acuC
  • product: acetoin utilization protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1782927..1784096
  • length: 1170
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGCAACAACATTCATCAAAAACTGCATATGTTTATTCAGATAAGTTATTACAATATCGA
    TTTCATGACCAACATCCCTTCAATCAAATGCGTTTAAAATTAACAACAGAGCTACTTTTG
    AATGCAAATTTATTGTCTCCAGAACAAATAGTACAACCTAGAATTGCAACAGGTGACGAA
    TTAATGTTAATTCATAAATATGATTACGTCGAAGCTATTAAGCATGCTTCACATGGCATT
    ATCAGTGAAGATGAGGCTAAGAAATATGGATTAAATGATGAAGAGAATGGTCAATTTAAG
    CATATGCACCGCCATAGTGCCACAATTGTTGGAGGCGCTTTAACTTTAGCAGATCTTATT
    ATGTCAGGCAAAGTATTAAATGGTTGTCACTTAGGTGGTGGTTTGCATCACGCTCAACCT
    GGTCGAGCAAGTGGTTTTTGTATATACAATGATATTGCAATTACCGCACAATACATAGCT
    AAAGAATACAATCAACGCGTTTTAATCATAGATACCGATGCACATCATGGAGATGGTACA
    CAATGGAGTTTCTATGCCGATAACCATGTTACTACTTATTCTATCCATGAAACCGGAAAG
    TTTCTTTTCCCAGGCTCTGGTCACTATACTGAACGCGGTGAAGATATCGGCTATGGACAC
    ACTGTAAATGTCCCACTTGAACCGTATACAGAAGATGCATCATTTTTGGAGTGTTTTAAA
    TTAACAGTTGAGCCTGTCGTAAAGAGTTTTAAACCTGATATTATTCTAAGCGTAAATGGT
    GTCGATATACATTATCGTGATCCACTAACTCATCTAAATTGTACGTTACATTCATTATAT
    GAAATTCCATATTTTGTAAAATATTTAGCTGATTCTTATACGAATGGAAAGGTAATTATG
    TTTGGTGGCGGAGGCTACAATATTTGGAGAGTCGTACCACGTGCATGGAGTCATGTATTC
    TTAAGTTTAATTGATCAACCAATTCAAAGTGGTTATTTACCGTTAGAATGGATTAATAAA
    TGGAAACATTATTCATCTGAATTATTACCTAAAAGATGGGAAGATCGTTTAAATGATTAT
    ACCTATGTCCCCCGCACAAAAGAAATTAGTGAAAAAAATAAAAAATTAGCTTTACATATA
    GCGAGTTGGTACGAATCTACTCGTCAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1170

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA1556 [new locus tag: SA_RS08775 ]
  • symbol: AcuC
  • description: acetoin utilization protein
  • length: 389
  • theoretical pI: 6.87927
  • theoretical MW: 44571.1
  • GRAVY: -0.413882

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:  
    CarbohydratesCentral carbohydrate metabolismPyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate NAD-independent protein deacetylase AcuC 
  • PFAM:
    Arginase (CL0302) Hist_deacetyl; Histone deacetylase domain (PF00850; HMM-score: 244.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.116
    • Ymax_pos: 11
    • Cmax: 0.125
    • Cmax_pos: 59
    • Smax: 0.199
    • Smax_pos: 1
    • Smean: 0.121
    • D: 0.118
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATGDELMLIHKYDYVEAIKHASHGIISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYIAKEYNQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFKLTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIMFGGGGYNIWRVVPRAWSHVFLSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTRQ

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulators: CcpA, CodY
    CcpA (TF) important in Carbon catabolismRegPrecise
    CodY (TF) important in Amino acid metabolismRegPrecise

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]