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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA2050 [new locus tag: SA_RS11780 ]
  • pan locus tag?: SAUPAN005705000
  • symbol: SA2050
  • pan gene symbol?: pbuG
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA2050 [new locus tag: SA_RS11780 ]
  • symbol: SA2050
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2309578..2310912
  • length: 1335
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    GTGAAAAACTATTTCCAGTTCGATAAATATGGAACAAACTTTAAAAGAGAAATCTTAGGC
    GGTATCACAACTTTCTTATCTATGGCCTATATTTTAGCAGTTAACCCGCAAGTTTTAAGT
    TTAGCAGGTGTTAAAGGCGTATCAGAAGATATGAAAATGGACCAAGGTGCCATTTTTGTA
    GCGACTGCATTAGCAGCATTTGTAGGCTCGCTATTCATGGGACTAATAGCTAAATATCCA
    ATCGCATTAGCACCAGGTATGGGATTAAATGCATTCTTTGCATTTACTGTTGTGTTAACC
    ATGGGTATTCCTTGGCAAGTTGGTTTAACAGGTGTTTTATTCTCAGGTATATTCTTTGCG
    ATATTAACCGTCACAGGGTTTAGGGAAGTTATTATTAATGCAATTCCTTATCAAATGAAG
    ATGGCTGTTTCAGCAGGTATAGGATTATTCATTACATTTGTAGGTTTACAAAGTTCGGGT
    ATTATAGTTAAAAATGAATCTACATTAGTAACATTGGGACATTTAACTGATCCACCAGTA
    CTTTTGGCGATATTCGGTATCGTTATTACAGTTATTTTATATGCAATTAAATTGCCGGGT
    TCTATCTTTATCGGTATGATCATCACAGCAATCGTTGGTATGTTCACTGGATTGATTCAA
    ATGCCATCTGGTATTGTAGGTAAGATTCCAAGTATTGAACCAACGTTCGGTGCTGCATTT
    GAAGCGTTTAAAGACCCAAGTCAATTATTAACGATACAGTTCTTAATTGTTATTTTAACG
    TTCTTATTTATTGATTTCTTTGATACAGCTGGTACATTAGTAGCTGTTGCTACTCAAGCA
    GGTATTATGAAAGATAATAAATTACCAAGAGCTGGTAGAGCATTGTTCTCAGATTCTTTA
    GCTACGATTGTAGGATCAGTTTTTGGAACAACTACAACAACTTCTTATATCGAATCAACT
    TCAGGTGTTGCTGTAGGTGCTAGAACAGGATTTGCTAGTATCGTAACAGGTTGTTGTTTC
    CTATTAGCGCTGTTCTTTAGTCCGTTAATCGCTGTTGTAACAAGTGCAGTTACGACACCA
    GCTTTAGTGGTGGTAGGTGTATTAATGGCTGCAAACTTTGCTGAGATAAACTGGAAAAGT
    TTTGAAGTTGCAGTGCCAGCATTCATTACAATCATTATGATGCCTTTATCATACTCAATT
    GCAACTGGTATTGCGTGTGGATTTATTTTCTATCCAATTACAATGCTTATCTCTAAAAAA
    CATAAAGAAGTACATCCGATAATGTATGTATTAATGGTACTATTCATTCTGTACTTCATA
    TTTGTTCATGGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1335

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA2050 [new locus tag: SA_RS11780 ]
  • symbol: SA2050
  • description: hypothetical protein
  • length: 444
  • theoretical pI: 8.72068
  • theoretical MW: 47395.5
  • GRAVY: 1.05068

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Nucleosides, purines and pyrimidines uracil-xanthine permease (TIGR00801; HMM-score: 13.4)
  • TheSEED  :
    • Hypoxanthine/guanine permease PbuG
    Nucleosides and Nucleotides Purines Xanthine Metabolism in Bacteria  Hypoxanthine/guanine permease PbuG
  • PFAM:
    APC (CL0062) Xan_ur_permease; Permease family (PF00860; HMM-score: 143.1)
    and 1 more
    no clan defined DUF5464; Family of unknown function (DUF5464) (PF17552; HMM-score: 13.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 13
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.198549
    • TAT(Tat/SPI): 0.020574
    • LIPO(Sec/SPII): 0.006314
  • predicted transmembrane helices (TMHMM): 13

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGVKGVSEDMKMDQGAIFVATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSGIIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSIEPTFGAAFEAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAGRALFSDSLATIVGSVFGTTTTTSYIESTSGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSIATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]