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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA2239 [new locus tag: SA_RS12865 ]
  • pan locus tag?: SAUPAN006006000
  • symbol: SA2239
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA2239 [new locus tag: SA_RS12865 ]
  • symbol: SA2239
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2514441..2516078
  • length: 1638
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGAATAAAGACAAGCAATTGCACAACGACAAAATCAATCTATCCCAATTAGTCTTATTA
    GGGTTAGGCTCTTTAATAGGATCTGGTTGGCTATTTGGTGCGTGGGAAGCATCATCAATA
    GCTGGACCAGTAGCAATCATATCATGGGTTCTTGGATTCCTAGTCATTGGAACCATTGCC
    TATAACTACATTGAAATCGGCACAATGTTTCCTCAATCAGGTGGCATGAGTAACTATGCC
    CAGTATACACATGGCTCATTATTAGGCTTTATTGCTGCTTGGGCGAATTGGGTGTCTTTG
    GTGACAATAATACCTATCGAAGCTGTGTCAGCTGTTCAATATATGAGTTCTTGGCCGTGG
    CATTGGGCGAAACCAATGAGATATTTAATGGAAAATGGCTCTATTAGCACATACGGATTG
    CTAGCTGTATATCTCATCATTGTTATTTTTTCATTATTAAACTATTGGTCCGTAAAACTT
    TTAACATCATTTACGAGTTTAATTTCTGTATTTAAATTAGGCGTACCCATGTTAACCATC
    ATCATGTTGATGTTATCAGGATTCGACACTTCAAATTACGGCCATTCGGCAAGCACATTT
    ATGCCTTACGGAAGTGCACCGATTTTTGCTGCAACAACAGCATCAGGGATTATTTTTTCA
    TTCAATTCATTCCAGACAATTATTAATATGGGTTCAGAAATTAAAAATCCTGAAAAAAAT
    ATCGCAAGAGGCATCGCTATTTCACTGTCAATCAGTGCAGTGTTGTACATCATTTTACAA
    AGTACGTTTATCACTTCTATGCCTCAATCAATGTTACAACATAGTGGATGGAATGGCATC
    AACTTCAATTCACCATTTGCAGATTTAGCTATCTTATTAGGAATTAATTGGCTCGCAATT
    TTACTATATATTGAAGCTTTTGTATCACCATTCGGTACTGGCGTGTCATTTGTCGCCGTT
    ACAGGTCGAGTTTTACGAGCAATGGAGAAAAATGGACATATCCCTAAATTTCTTGGGAAG
    ATGAATGAAAAATATCATATCCCACGTGTAGCAATCATCTTTAATGCCATCATTAGTATG
    ATTATGGTTACATTATTTAGAGATTGGGGTACGCTAGCAGCAGTTATTTCTACTGCAACT
    TTAGTAGCCTATTTAACTGGCCCAACGACAGTGATTGCATTAAGAAAAATGGGACCAACA
    ATGACTCGTCCATTTAGAGCAAAAATTTTAAAAGTAATGGCACCATTATCATTTGTATTA
    GCTTCATTAGCTATATATTGGGCAATGTGGCCAACAACGGCTGAAGTTATTTTAATCATT
    ATACTTGGATTACCAATCTACTTCTTCTATGAATACCGTATGAATTGGCGTAATACAAAG
    AAACAAATTGGTGGTAGCTTATGGATTATTGTATATTTAATCGTGCTATCAATACTGTCA
    TTTATAGGAAGCAAAGAATTTAAAGGCTTAAATATGATTCACTATCCATTTGACTTTATC
    GTTATTATTGTTGTGGCGCTTATATTCTATTACATCGGTACAACGAGTTCATTTGAAAGC
    GTCTATTTCCGTCGCGCAACACGAATCAATACAAAGATGCGCGAGTCACTAAATAATGAA
    TCAAAGTCATCTCATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1638

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA2239 [new locus tag: SA_RS12865 ]
  • symbol: SA2239
  • description: hypothetical protein
  • length: 545
  • theoretical pI: 10.0252
  • theoretical MW: 60654.3
  • GRAVY: 0.608257

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesamino acid transporter (TIGR00909; HMM-score: 172.3)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminescationic amino acid transport permease (TIGR00906; HMM-score: 96)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesL-type amino acid transporter (TIGR00911; HMM-score: 94.6)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminestransporter, basic amino acid/polyamine antiporter (APA) family (TIGR00905; HMM-score: 89.9)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesethanolamine permease (TIGR00908; HMM-score: 71.1)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesamino acid permease (yeast) (TIGR00913; HMM-score: 56.8)
    histidine-histamine antiporter (TIGR04298; HMM-score: 48.4)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesGABA permease (TIGR01773; HMM-score: 47.8)
    putrescine-ornithine antiporter (TIGR04299; HMM-score: 34.5)
    putative glutamate/gamma-aminobutyrate antiporter (TIGR03813; HMM-score: 31.1)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesarginine-ornithine antiporter (TIGR03810; HMM-score: 29.2)
    MetabolismEnergy metabolismElectron transportcytochrome c oxidase, subunit II (TIGR02866; EC 1.9.3.1; HMM-score: 4.8)
  • TheSEED:  
    Amino acid-proton symporter YbeC 
  • PFAM:
    APC (CL0062) AA_permease_2; Amino acid permease (PF13520; HMM-score: 144.9)
    AA_permease; Amino acid permease (PF00324; HMM-score: 106.2)
    no clan definedAc76; Orf76 (Ac76) (PF05814; HMM-score: 19.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 14
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.184
    • Ymax_pos: 37
    • Cmax: 0.157
    • Cmax_pos: 37
    • Smax: 0.293
    • Smax_pos: 33
    • Smean: 0.177
    • D: 0.181
  • predicted transmembrane helices (TMHMM): 14

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MNKDKQLHNDKINLSQLVLLGLGSLIGSGWLFGAWEASSIAGPVAIISWVLGFLVIGTIAYNYIEIGTMFPQSGGMSNYAQYTHGSLLGFIAAWANWVSLVTIIPIEAVSAVQYMSSWPWHWAKPMRYLMENGSISTYGLLAVYLIIVIFSLLNYWSVKLLTSFTSLISVFKLGVPMLTIIMLMLSGFDTSNYGHSASTFMPYGSAPIFAATTASGIIFSFNSFQTIINMGSEIKNPEKNIARGIAISLSISAVLYIILQSTFITSMPQSMLQHSGWNGINFNSPFADLAILLGINWLAILLYIEAFVSPFGTGVSFVAVTGRVLRAMEKNGHIPKFLGKMNEKYHIPRVAIIFNAIISMIMVTLFRDWGTLAAVISTATLVAYLTGPTTVIALRKMGPTMTRPFRAKILKVMAPLSFVLASLAIYWAMWPTTAEVILIIILGLPIYFFYEYRMNWRNTKKQIGGSLWIIVYLIVLSILSFIGSKEFKGLNMIHYPFDFIVIIVVALIFYYIGTTSSFESVYFRRATRINTKMRESLNNESKSSH

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]