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NCBI: 10-JUN-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0868 [new locus tag: SACOL_RS04455 ]
  • pan locus tag?: SAUPAN002810000
  • symbol: SACOL0868
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL0868 [new locus tag: SACOL_RS04455 ]
  • symbol: SACOL0868
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 891876..892112
  • length: 237
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGGATAATCATAATCAATGTAATTATGTGAATCCACAAAATGTTTCACTTGACTGGGAA
    TGTTTTATAATTAGTAAAAGTGAAATGTTGTTAGATGGTGTACCAAATGAACTTATCAAC
    ACTTGGTTAGATAAAGACATTATTACACCATTTTCGATAAGAAATGATGAAATAAACTTT
    AAAACAAAAGATATTTGGGATGCACTAATACATCATAATTGGTACTACTCAAATTAA
    60
    120
    180
    237

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL0868 [new locus tag: SACOL_RS04455 ]
  • symbol: SACOL0868
  • description: hypothetical protein
  • length: 78
  • theoretical pI: 4.29567
  • theoretical MW: 9344.39
  • GRAVY: -0.526923

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • FIG01108334: hypothetical protein
  • PFAM:

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003242
    • TAT(Tat/SPI): 0.000101
    • LIPO(Sec/SPII): 0.001002
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MDNHNQCNYVNPQNVSLDWECFIISKSEMLLDGVPNELINTWLDKDIITPFSIRNDEINFKTKDIWDALIHHNWYYSN

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator: SigB* (activation) regulon
    SigB*(sigma factor)controlling a large regulon involved in stress/starvation response and adaptation [1] [2]   other strains

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. Markus Bischoff, Paul Dunman, Jan Kormanec, Daphne Macapagal, Ellen Murphy, William Mounts, Brigitte Berger-Bächi, Steven Projan
    Microarray-based analysis of the Staphylococcus aureus sigmaB regulon.
    J Bacteriol: 2004, 186(13);4085-99
    [PubMed:15205410] [WorldCat.org] [DOI] (P p)
  2. Jan Pané-Farré, Beate Jonas, Konrad Förstner, Susanne Engelmann, Michael Hecker
    The sigmaB regulon in Staphylococcus aureus and its regulation.
    Int J Med Microbiol: 2006, 296(4-5);237-58
    [PubMed:16644280] [WorldCat.org] [DOI] (P p)

Relevant publications[edit | edit source]