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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0897 [new locus tag: SACOL_RS04605 ]
  • pan locus tag?: SAUPAN002859000
  • symbol: SACOL0897
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL0897 [new locus tag: SACOL_RS04605 ]
  • symbol: SACOL0897
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 909954..911411
  • length: 1458
  • essential: unknown

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    TTGGAAGATGTTACAAACGAAGAAGTATTTGAAATGATTGATAGCAGAACCGGTGTTTTA
    AATGCTAATGATTGGAAAAGTCAATTAAGGCGTTCTGCTACTACACAAGCATTGAAAAAA
    ACGACTACAAATGCTGAAATCATATTGTGTAATGATGAGAGTTTAAAAGGGCTAGTACAA
    TATGACGCTTTTGAAAAAGTAACCAAACTGAAACGTCTACCGTATTGGAGGTCAAAAGGA
    GATACGAATTATTATTGGGCTGATATAGATACCACACATGTGATTTCACATATTGATAAA
    TTGTATAATGTGCAGTTTAGCCGTGATCTTATTGATACTGTAATTGAAAAGGAAGCTTAT
    CAAAATAGATTTCACCCTATTAAATCGATGATTGAATCTAAATCATGGGACGGAATCAAA
    AGAATTGAAACGCTCTTCATTGATTATTTAGGTGCTGAAGATAACCACTATAATAGAGAA
    GTTACAAAAAAATGGATGATGGGCGCAGTTGCTAGAATCTATCAGCCAGGTATTAAATAT
    GATTCCATGATTATTTTATATGGTGGTCAAGGTGTTGGAAAATCTACGGCAGTGAGTAAA
    TTGGGAGGTCATTGGTATAACCAAAGTATTAAAACGTTTAAAGGTGATGAGGTCTATAAG
    AAATTGCAGGGTTCTTGGATATGTGAAATTGAAGAACTGTCGGCATTTCAAAAGTCTACT
    ATTGAAGATATTAAGGGGTTTATAAGTGCTATTGTAGATATTTATAGAGCTTCGTATGGT
    AAACGAACAGAGCGTCATCCTAGACAGTGTGTGTTTGTAGGGACAACCAATAACTATGAG
    TTTTTAAAAGACCAAACAGGCAATCGTCGTTTTTTCCCTATTACGACAGATAAAAATAAA
    GCAACTAAAAGCCCGTTTGACGATCTAACACCAGATGTTGTGCAACAAATGTTTGCTGAA
    GCTAAAGTATATTTTGATGAGGATCCGACGGATAAAGCATTGTTATTAGATAAAGAAGCG
    AGTGAGATGGCTTTAAAAGTCCAAGAAGCTCATTCTGAAAAAGATGCTTTAGTTGGAGAA
    ATAGAAGAATTCCTTGAACGTCCTATTCCGTCAGACTATTGGTATAGAACGTTAGAAGAA
    AAAAGAGTGTCTGCGCATGATGTTATAGACCAAGACTATATTAAATTATATGGTGATGGT
    AAATTGATTGAATTACCGAATACAAAACCAGGTGCTTATGTATGGCGTGACAAGGTATGT
    AGCATGGAAATTTGGAAAGTGATGATGAAACGAGATGACCAACCACAACAACACCATTTA
    AGAAAAATTGATAAAGCGTTAAGAAATACAAATTATTGTGACACTGTGAAAAAGCAAACG
    CGATATGGTGAAGGTATTGGTAAGCAATATGGCTTTAGTGTAGATTTAGCTTCTTATTAT
    AAGAATCTTAAAGTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1458

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL0897 [new locus tag: SACOL_RS04605 ]
  • symbol: SACOL0897
  • description: hypothetical protein
  • length: 485
  • theoretical pI: 7.05745
  • theoretical MW: 56364.5
  • GRAVY: -0.661856

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Cellular processesCellular processesChemotaxis and motilityflagellar biosynthesis protein FlhF (TIGR03499; HMM-score: 16.8)
  • TheSEED:  
    Phages, Prophages, Transposable elements, PlasmidsPathogenicity islandsStaphylococcal pathogenicity islands SaPI Hypothetical SAV0791 homolog in superantigen-encoding pathogenicity islands SaPI 
  • PFAM:
    P-loop_NTPase (CL0023) VirE; Virulence-associated protein E (PF05272; HMM-score: 241.3)
    RNA_helicase; RNA helicase (PF00910; HMM-score: 17.9)
    AAA_24; AAA domain (PF13479; HMM-score: 16.2)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 14.7)
    AAA_28; AAA domain (PF13521; HMM-score: 14.3)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 12.3)
    SRP54; SRP54-type protein, GTPase domain (PF00448; HMM-score: 11.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.122
    • Ymax_pos: 48
    • Cmax: 0.112
    • Cmax_pos: 23
    • Smax: 0.181
    • Smax_pos: 44
    • Smean: 0.102
    • D: 0.114
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MEDVTNEEVFEMIDSRTGVLNANDWKSQLRRSATTQALKKTTTNAEIILCNDESLKGLVQYDAFEKVTKLKRLPYWRSKGDTNYYWADIDTTHVISHIDKLYNVQFSRDLIDTVIEKEAYQNRFHPIKSMIESKSWDGIKRIETLFIDYLGAEDNHYNREVTKKWMMGAVARIYQPGIKYDSMIILYGGQGVGKSTAVSKLGGHWYNQSIKTFKGDEVYKKLQGSWICEIEELSAFQKSTIEDIKGFISAIVDIYRASYGKRTERHPRQCVFVGTTNNYEFLKDQTGNRRFFPITTDKNKATKSPFDDLTPDVVQQMFAEAKVYFDEDPTDKALLLDKEASEMALKVQEAHSEKDALVGEIEEFLERPIPSDYWYRTLEEKRVSAHDVIDQDYIKLYGDGKLIELPNTKPGAYVWRDKVCSMEIWKVMMKRDDQPQQHHLRKIDKALRNTNYCDTVKKQTRYGEGIGKQYGFSVDLASYYKNLKV

Experimental data[edit source | edit]

  • experimental localization: Cytoplasmic [1]

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int. J. Med. Microbiol.: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

Relevant publications[edit source | edit]