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COLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS01830 [old locus tag: SACOL0364 ]
  • pan locus tag?:
  • symbol: SACOL_RS01830
  • pan gene symbol?:
  • synonym:
  • product: transcriptional regulator

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS01830 [old locus tag: SACOL0364 ]
  • symbol: SACOL_RS01830
  • product: transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 372895..373332
  • length: 438
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_002951 (372895..373332) NCBI
  • BioCyc: G1G4B-377 BioCyc
  • MicrobesOnline: see SACOL0364

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGGAAAGGCATCATATGATATTAAGCCAGGTACATTTAAATATATTGAGTCAGAGATA
    TATAACCTACAAGAGAACAAGAAAGAGATAAATAGATTGAGAATGGAGATACTTAACCCA
    ACGAAAGAACTAGACACCAACATTGTGTATGGACCGTTACAAAAAGGAGAGCCAGTTAGA
    ACAACTGAGTTAATGGCGACAAGGTTATTGACTAATAAGATGTTACGTAACTTAGAAGAG
    ATGGTTGAAGCAGTTGAAAGTGAGTACTTAAAGTTACCTGAAGATCATAAGAAAGTAATA
    AGGTTAAAGTATTGGAATAAAGATAAGAAGCTAAAGATAGAACAAATAGGGGATGCTTGT
    CACATGCATCGCAATACAGTTACTACAATACGAAAGAACTTTGTTAAAGCGATAGCGTAT
    CATGCAGGTATCAAATAA
    60
    120
    180
    240
    300
    360
    420
    438

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL_RS01830 [old locus tag: SACOL0364 ]
  • symbol: SACOL_RS01830
  • description: transcriptional regulator
  • length: 145
  • theoretical pI: 9.92748
  • theoretical MW: 17035.8
  • GRAVY: -0.686207

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage transcriptional regulator, RinA family (TIGR01636; HMM-score: 61.4)
    Signal transduction Regulatory functions DNA interactions phage transcriptional regulator, RinA family (TIGR01636; HMM-score: 61.4)
    and 2 more
    RNA polymerase sigma factor, sigma-70 family (TIGR02937; HMM-score: 19.8)
    RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1 (TIGR02984; HMM-score: 14.2)
  • TheSEED: see SACOL0364
  • PFAM:
    HTH (CL0123) HTH_23; Homeodomain-like domain (PF13384; HMM-score: 20.2)
    and 2 more
    Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 15.8)
    HTH_AraC; Bacterial regulatory helix-turn-helix proteins, AraC family (PF00165; HMM-score: 12.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005008
    • TAT(Tat/SPI): 0.000253
    • LIPO(Sec/SPII): 0.000374
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MGKASYDIKPGTFKYIESEIYNLQENKKEINRLRMEILNPTKELDTNIVYGPLQKGEPVRTTELMATRLLTNKMLRNLEEMVEAVESEYLKLPEDHKKVIRLKYWNKDKKLKIEQIGDACHMHRNTVTTIRKNFVKAIAYHAGIK

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: see SACOL0364
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]