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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS02175 [old locus tag: SACOL0432 ]
  • pan locus tag?: SAUPAN001906000
  • symbol: SACOL_RS02175
  • pan gene symbol?: parB
  • synonym:
  • product: chromosome partitioning protein ParB

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS02175 [old locus tag: SACOL0432 ]
  • symbol: SACOL_RS02175
  • product: chromosome partitioning protein ParB
  • replicon: chromosome
  • strand: +
  • coordinates: 438948..439793
  • length: 846
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (438948..439793) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    GTGAGTGAATTGTCAAAAAGTGAAGATCAACGTATTACTAAAACAAAAGATGAACAAATT
    AAGCAAATAGATATATCGGATATCAAACCGAATCCGTATCAGCCCCGAAAAACTTTCGAT
    GAAAATCATTTAAATGATTTGGCAGATTCAATTAAGCAATATGGAATTTTGCAACCAATT
    GTGCTTAGAAAAACAGTTCAAGGTTATTACATTGTAGTTGGTGAAAGAAGGTTTAGAGCT
    TCGAAAATTGCTGGTCTAAAATACGTATCAGCGATTATCAAAGATTTAACAGATGAAGAT
    ATGATGGAACTGGCGGTCATCGAAAATTTACAACGAGAAGACTTAAATGCGATTGAAGAA
    GCTGAAAGTTATCAACGTTTGATGACAGATTTGAAAATTACACAACAAGAAGTAGCGAAA
    CGATTGAGTAAGTCGCGCCCGTATATAGCGAATATGTTGAGGTTATTACATTTGCCGAAA
    AAGATTGCTGACATGGTAAAAGATGGGCGACTGACAAGTGCACATGGACGAACGTTATTG
    GCAATTAAAGATGAACAACAAATGCTTAGGTTAGCGAAACGGGTTGTTAAAGAAAAGTGG
    AGTGTCAGATATTTAGAAAACCATGTTAATGAATTAAAAAATGTTTCGTCAAAGTCGGAA
    ACAGACAAAGTAGATATAACTAAGCCTAAATTTATAAAGCAGCAAGAACGACAGTTGCGA
    GAACAGTATGGTACCAAAGTAGATATATCAATAAAAAAATCGGTTGGTAAAATCTCATTT
    GAGTTTGATTCACAAGAAGATTTTGTGAGAATAATTGAACAATTAAATCGTAGGTATGGT
    AAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    846

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS02175 [old locus tag: SACOL0432 ]
  • symbol: SACOL_RS02175
  • description: chromosome partitioning protein ParB
  • length: 281
  • theoretical pI: 10.0114
  • theoretical MW: 32855.6
  • GRAVY: -0.712456

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    nucleoid occlusion protein (TIGR04285; HMM-score: 248.1)
    ParB/RepB/Spo0J family partition protein (TIGR00180; HMM-score: 195.1)
    PRTRC system ParB family protein (TIGR03734; HMM-score: 118.7)
    Genetic information processingMobile and extrachromosomal element functionsPlasmid functionsplasmid partitioning protein RepB (TIGR03454; HMM-score: 70.9)
  • TheSEED:
  • PFAM:
    ParBc (CL0248) ParBc; ParB-like nuclease domain (PF02195; HMM-score: 94.5)
    no clan definedLatarcin; Latarcin precursor (PF10279; HMM-score: 22.3)
    PDDEXK (CL0236) DUF1016; Protein of unknown function (DUF1016) (PF06250; HMM-score: 17.4)
    HTH (CL0123) KorB; KorB domain (PF08535; HMM-score: 17.1)
    HTH_3; Helix-turn-helix (PF01381; HMM-score: 16.7)
    MarR_2; MarR family (PF12802; HMM-score: 13.7)
    MerR_2; MerR HTH family regulatory protein (PF13591; HMM-score: 13.3)
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 13)
    no clan definedStatherin; Statherin (PF03875; HMM-score: 12.9)
    HTH (CL0123) TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 12.6)
    no clan definedCbeA_antitoxin; CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A (PF06154; HMM-score: 12.5)
    HTH (CL0123) HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 12.1)
    HTH_37; Helix-turn-helix domain (PF13744; HMM-score: 9.6)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.103
    • Ymax_pos: 11
    • Cmax: 0.103
    • Cmax_pos: 39
    • Smax: 0.141
    • Smax_pos: 2
    • Smean: 0.103
    • D: 0.103
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 486201924 NCBI
  • RefSeq: WP_001550052 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MSELSKSEDQRITKTKDEQIKQIDISDIKPNPYQPRKTFDENHLNDLADSIKQYGILQPIVLRKTVQGYYIVVGERRFRASKIAGLKYVSAIIKDLTDEDMMELAVIENLQREDLNAIEEAESYQRLMTDLKITQQEVAKRLSKSRPYIANMLRLLHLPKKIADMVKDGRLTSAHGRTLLAIKDEQQMLRLAKRVVKEKWSVRYLENHVNELKNVSSKSETDKVDITKPKFIKQQERQLREQYGTKVDISIKKSVGKISFEFDSQEDFVRIIEQLNRRYGK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS02175 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]