From AureoWiki
Jump to: navigation, search
NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS03605 [old locus tag: SACOL0701 ]
  • pan locus tag?: SAUPAN002522000
  • symbol: SACOL_RS03605
  • pan gene symbol?: nupG
  • synonym:
  • product: nucleoside permease

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS03605 [old locus tag: SACOL0701 ]
  • symbol: SACOL_RS03605
  • product: nucleoside permease
  • replicon: chromosome
  • strand: +
  • coordinates: 726732..727961
  • length: 1230
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (726732..727961) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGTTTTTATTAATCAACATTATTGGTCTAATTGTATTTCTTGGTATTGCGGTATTATTT
    TCAAGAGATCGCAAAAATATCCAATGGCAATCAATTGGGATCTTAGTTGTTTTAAACCTG
    TTTTTAGCATGGTTCTTTATTTATTTTGATTGGGGTCAAAAAGCAGTAAGAGGAGCAGCC
    AATGGTATCGCTTGGGTAGTTCAGTCAGCGCATGCTGGTACAGGTTTTGCATTTGCAAGT
    TTGACAAATGTTAAAATGATGGATATGGCTGTTGCAGCCTTATTCCCAATATTATTAATA
    GTGCCATTATTTGATATCTTAATGTACTTTAATATTTTACCGAAAATTATTGGAGGTATT
    GGTTGGTTACTAGCTAAAGTAACAAGACAACCTAAATTCGAGTCATTCTTTGGGATAGAA
    ATGATGTTCTTAGGAAATACTGAAGCATTAGCCGTATCAAGTGAGCAACTAAAACGTATG
    AATGAAATGCGTGTATTAACAATCGCAATGATGTCAATGAGCTCTGTATCGGGAGCTATT
    GTAGGTGCGTATGTACAAATGGTACCAGGAGAACTGGTACTAACGGCAATTCCACTAAAT
    ATCGTTAACGCGATTATTGTGTCATGCTTGTTGAATCCAGTAAGTGTTGAAGAGAAAGAA
    GATATTATTTACAGTCTTAAAAACAATGAAGTTGAACGTCAACCATTCTTCTCATTCCTT
    GGAGATTCTGTATTAGCAGCAGGTAAATTAGTATTAATCATCATCGCATTTGTTATTAGT
    TTTGTAGCGTTAGCTGATCTATTTGATCGTTTTATCAATTTGATTACAGGATTGATAGCA
    GGATGGATAGGCATAAAAGGTAGTTTCGGTTTAAACCAAATTTTAGGTGTGTTTATGTAT
    CCATTTGCGCTATTACTCGGTTTACCTTATGATGAAGCGTGGTTGGTAGCACAACAAATG
    GCTAAGAAAATTGTTACAAATGAATTTGTTGTTATGGGTGAAATTTCTAAAGATATTGCA
    TCTTATACACCACACCATCGTGCGGTTATTACAACATTCTTAATTTCATTTGCAAACTTC
    TCAACGATTGGTATGATTATCGGTACATTGAAAGGCATTGTTGATAAAAAGACATCAGAC
    TTTGTATCTAAATATGTACCTATGATGCTATTATCAGGTATCCTAGTTTCATTATTAACA
    GCAGCTTTCGTTGGTTTATTTGCATGGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1230

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS03605 [old locus tag: SACOL0701 ]
  • symbol: SACOL_RS03605
  • description: nucleoside permease
  • length: 409
  • theoretical pI: 8.38842
  • theoretical MW: 45015.6
  • GRAVY: 0.900244

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsNucleosides, purines and pyrimidinesnucleoside transporter, NupC family (TIGR00804; HMM-score: 322.1)
  • TheSEED:
  • PFAM:
    no clan definedNucleos_tra2_C; Na+ dependent nucleoside transporter C-terminus (PF07662; HMM-score: 157.5)
    Nucleos_tra2_N; Na+ dependent nucleoside transporter N-terminus (PF01773; HMM-score: 65.9)
    DUF3290; Protein of unknown function (DUF3290) (PF11694; HMM-score: 13.6)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.137
    • Ymax_pos: 11
    • Cmax: 0.206
    • Cmax_pos: 30
    • Smax: 0.241
    • Smax_pos: 2
    • Smean: 0.179
    • D: 0.153
  • predicted transmembrane helices (TMHMM): 10

Accession numbers[edit source | edit]

  • GI: 446401424 NCBI
  • RefSeq: WP_000479279 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MFLLINIIGLIVFLGIAVLFSRDRKNIQWQSIGILVVLNLFLAWFFIYFDWGQKAVRGAANGIAWVVQSAHAGTGFAFASLTNVKMMDMAVAALFPILLIVPLFDILMYFNILPKIIGGIGWLLAKVTRQPKFESFFGIEMMFLGNTEALAVSSEQLKRMNEMRVLTIAMMSMSSVSGAIVGAYVQMVPGELVLTAIPLNIVNAIIVSCLLNPVSVEEKEDIIYSLKNNEVERQPFFSFLGDSVLAAGKLVLIIIAFVISFVALADLFDRFINLITGLIAGWIGIKGSFGLNQILGVFMYPFALLLGLPYDEAWLVAQQMAKKIVTNEFVVMGEISKDIASYTPHHRAVITTFLISFANFSTIGMIIGTLKGIVDKKTSDFVSKYVPMMLLSGILVSLLTAAFVGLFAW

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS03605 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]