From AureoWiki
Jump to: navigation, search
NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS07135 [old locus tag: SACOL1402 ]
  • pan locus tag?: SAUPAN003759000
  • symbol: SACOL_RS07135
  • pan gene symbol?:
  • synonym:
  • product: aminopeptidase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS07135 [old locus tag: SACOL1402 ]
  • symbol: SACOL_RS07135
  • product: aminopeptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 1412687..1413718
  • length: 1032
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (1412687..1413718) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGAACCAATATTAGAAATGATTAAAACATTAACAGGTATTAATAGTCCTTCAGGAGAC
    ACAGAAGAAGCAATTCAATTTGTCGAAAAATATGCAAAAGACTTGGGTTATCAAACAACA
    CTAACAAATAAAGGTGCGTTATTAATAACAGTGCCAGGCAAAAATGATGAAGTACAACGC
    TGTATTACTGCTCATGTTGATACTTTAGGTGCAATGGTTAAAGAAATTAAAGAAGATGGT
    CGCTTAGCAATAGAATTAATTGGAGGATTCACGTATAACGCGATTGAGGGTGAATATTGC
    CAAATTAAAACTGATGCTGGTCAAATATATACAGGAACAATTTGTCTGCATGAAACAAGT
    GTTCATGTATATAGAAATAATCATGAAATACCTAGAGATCAAAAGCATATGGAAATAAGA
    ATTGATGAAGTAACTACATCAGAAGAAGATACAAAGAGTTTAGGTATTTCAGTAGGTAAT
    TTTGTTAGCTTTGATCCACGTACAGTTATCACGTCATCAGGTTTTATTAAATCTCGTCAT
    TTAGATGATAAAGCTAGCGTAGCGATGATACTACAATTACTAAAGAAATTAAAAGAAGAG
    CAAATAATATTACCACATACAACGCAATTTTATATTTCTAATAACGAAGAAATAGGTTAC
    GGTGCAAATGCATCAATTGATTCGAAAATCAAAGAATATATTGCATTAGATATGGGCGCG
    TTGGGAGACGGTCAAGCATCGGATGAATATACAGTTTCTATTTGTGCCAAAGATGCTTCA
    GGTCCATATCATAAGCAATTGAAATCGCACCTAGTTAATCTTTGCAAAATAAATAACATT
    CCATATAAAGTAGACATATATCCATATTATGGTTCAGATGCTTCAGCAGCTTTACATGCT
    GGTGCGGATATCAGACATGGTTTATTTGGCGCTGGCATTGAATCATCTCATGCAATGGAA
    CGAACACATATTGATTCTATTAAAGCGACAGAGAAATTACTATATGCATATTGCTTATCA
    CCAATTGAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1032

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS07135 [old locus tag: SACOL1402 ]
  • symbol: SACOL_RS07135
  • description: aminopeptidase
  • length: 343
  • theoretical pI: 5.25114
  • theoretical MW: 37854.6
  • GRAVY: -0.262099

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    hydrolase, peptidase M42 family (TIGR03106; HMM-score: 328)
    Genetic information processingProtein fateDegradation of proteins, peptides, and glycopeptidesglutamyl aminopeptidase (TIGR03107; EC 3.4.11.7; HMM-score: 72.1)
    peptidase T-like protein (TIGR01883; HMM-score: 19.4)
    N-acetyl-ornithine/N-acetyl-lysine deacetylase (TIGR01902; HMM-score: 17.3)
    Xaa-His dipeptidase (TIGR01893; EC 3.4.13.20; HMM-score: 16.5)
    MetabolismAmino acid biosynthesisAspartate familysuccinyl-diaminopimelate desuccinylase (TIGR01900; EC 3.5.1.18; HMM-score: 15.5)
  • TheSEED:
  • PFAM:
    Peptidase_MH (CL0035) Peptidase_M42; M42 glutamyl aminopeptidase (PF05343; HMM-score: 295.1)
    Peptidase_M20; Peptidase family M20/M25/M40 (PF01546; HMM-score: 31.7)
    Peptidase_M28; Peptidase family M28 (PF04389; HMM-score: 17)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.148
    • Ymax_pos: 25
    • Cmax: 0.183
    • Cmax_pos: 25
    • Smax: 0.214
    • Smax_pos: 1
    • Smean: 0.112
    • D: 0.134
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446355508 NCBI
  • RefSeq: WP_000433363 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MEPILEMIKTLTGINSPSGDTEEAIQFVEKYAKDLGYQTTLTNKGALLITVPGKNDEVQRCITAHVDTLGAMVKEIKEDGRLAIELIGGFTYNAIEGEYCQIKTDAGQIYTGTICLHETSVHVYRNNHEIPRDQKHMEIRIDEVTTSEEDTKSLGISVGNFVSFDPRTVITSSGFIKSRHLDDKASVAMILQLLKKLKEEQIILPHTTQFYISNNEEIGYGANASIDSKIKEYIALDMGALGDGQASDEYTVSICAKDASGPYHKQLKSHLVNLCKINNIPYKVDIYPYYGSDASAALHAGADIRHGLFGAGIESSHAMERTHIDSIKATEKLLYAYCLSPIE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS07135 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]