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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS11390 [old locus tag: SACOL2167 ]
  • pan locus tag?: SAUPAN005567000
  • symbol: SACOL_RS11390
  • pan gene symbol?: htsA
  • synonym:
  • product: ABC transporter substrate-binding protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS11390 [old locus tag: SACOL2167 ]
  • symbol: SACOL_RS11390
  • product: ABC transporter substrate-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2245863..2246846
  • length: 984
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (2245863..2246846) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGAGGTCTAAAAACTTTTAGTATATTGGGATTAATAGTTGCCTTACTTTTAGTTGCA
    GCTTGTGGTAATACGGATAATTCAAGTAAAAAAGAATCATCAACTAAAGATACTATTTCG
    GTAAAAGATGAAAATGGTACAGTAAAAGTACCTAAAGATGCAAAACGTATCGTTGTATTA
    GAGTACTCATTTGCAGATGCATTAGCAGCATTAGACGTTAAACCAGTTGGTATTGCTGAT
    GATGGTAAGAAAAAACGTATCATTAAACCAGTTAGAGAAAAAATTGGGGATTATACTTCT
    GTAGGTACACGTAAACAGCCAAACTTAGAAGAAATTAGTAAATTAAAACCGGATTTAATT
    ATCGCTGATAGCAGTAGACATAAAGGTATTAATAAAGAATTAAACAAAATTGCACCAACA
    TTATCATTAAAGAGTTTTGATGGAGACTACAAACAAAATATTAATTCGTTCAAAACAATT
    GCTAAAGCTTTAAATAAAGAAAAAGAAGGCGAAAAACGTCTTGCTGAGCATGATAAATTA
    ATCAATAAGTATAAAGATGAAATTAAATTTGATAGAAATCAAAAAGTGCTTCCAGCAGTA
    GTTGCTAAAGCTGGTTTATTAGCACATCCAAACTATTCATATGTTGGACAATTTTTAAAC
    GAACTAGGATTTAAAAATGCATTAAGTGACGATGTAACAAAAGGTTTAAGTAAATATTTG
    AAAGGACCTTACTTACAATTAGACACTGAACATTTAGCTGATTTAAATCCAGAGCGTATG
    ATCATTATGACAGATCATGCTAAAAAAGATTCTGCTGAATTCAAGAAGTTACAAGAAGAT
    GCAACATGGAAAAAGTTGAATGCAGTTAAAAATAATCGCGTGGATATTGTTGACCGTGAT
    GTTTGGGCAAGATCTCGTGGCTTAATTTCTTCTGAAGAAATGGCTAAAGAACTTGTTGAA
    TTATCAAAAAAAGAACAAAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    984

Protein[edit source | edit]

Protein Data Bank: 3EIW
Protein Data Bank: 3EIX
Protein Data Bank: 3LHS
Protein Data Bank: 3LI2

General[edit source | edit]

  • locus tag: SACOL_RS11390 [old locus tag: SACOL2167 ]
  • symbol: SACOL_RS11390
  • description: ABC transporter substrate-binding protein
  • length: 327
  • theoretical pI: 10.05
  • theoretical MW: 36590.9
  • GRAVY: -0.562385

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    heme ABC transporter, heme-binding protein isdE (TIGR03659; HMM-score: 95)
    putative ABC transporter PGF-CTERM-modified substrate-binding protein (TIGR04281; HMM-score: 15.7)
    proposed F420-0 ABC transporter, periplasmic F420-0 binding protein (TIGR03868; HMM-score: 13.5)
  • TheSEED:
  • PFAM:
    Chelatase (CL0043) Peripla_BP_2; Periplasmic binding protein (PF01497; HMM-score: 113.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 9.68
    • Cellwall Score: 0.17
    • Extracellular Score: 0.16
    • Internal Helix: 1
  • LocateP:
  • SignalP: Signal peptide length 32 aa
    • Ymax: 0.423
    • Ymax_pos: 32
    • Cmax: 0.283
    • Cmax_pos: 32
    • Smax: 0.899
    • Smax_pos: 17
    • Smean: 0.747
    • D: 0.549
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 447137405 NCBI
  • RefSeq: WP_001214661 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MRGLKTFSILGLIVALLLVAACGNTDNSSKKESSTKDTISVKDENGTVKVPKDAKRIVVLEYSFADALAALDVKPVGIADDGKKKRIIKPVREKIGDYTSVGTRKQPNLEEISKLKPDLIIADSSRHKGINKELNKIAPTLSLKSFDGDYKQNINSFKTIAKALNKEKEGEKRLAEHDKLINKYKDEIKFDRNQKVLPAVVAKAGLLAHPNYSYVGQFLNELGFKNALSDDVTKGLSKYLKGPYLQLDTEHLADLNPERMIIMTDHAKKDSAEFKKLQEDATWKKLNAVKNNRVDIVDRDVWARSRGLISSEEMAKELVELSKKEQK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS11390 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]