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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS12470 [old locus tag: SACOL2375 ]
  • pan locus tag?: SAUPAN005896000
  • symbol: SACOL_RS12470
  • pan gene symbol?: cobI
  • synonym:
  • product: magnesium transporter CorA

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS12470 [old locus tag: SACOL2375 ]
  • symbol: SACOL_RS12470
  • product: magnesium transporter CorA
  • replicon: chromosome
  • strand: +
  • coordinates: 2433234..2434178
  • length: 945
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (2433234..2434178) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGATTACTTCATTCAGACATTCTGAAGATATAGATAAACATATTATAAAAACACCATTA
    GATCATACAGCGTCATGGATTAATGTAGTAGAACCAGACCGAGAAGAAATTGAAAATCTT
    ATGGAACAATATAATATACCTGAAGACTTTATACGTGACCCTTTGGACTCAGAAGAAAGT
    TCCCGTATTGAATATGACGAAGATACTGGTTACTCATTAATCATTATTGATTTACCTATC
    GTCAATTCAACTAATCGTAGCGTTCTATCTTTTGTAACGATTCCATTAGGCATTATTATT
    GGCAACGGTATTATCGTAACAGTTTGTGACGCTGAAAATGAATTTTTAGAAAATTTACCT
    AAGCGTGATATTAATTTAAAATTTCACAGCAGATTTGCATTAGAAATTTTAACTACTATT
    GCCGACCATTATAATCGTAACTTACGATTACTTAATAAAAGTAGAATTCGTATTGAGAAA
    GAACTAAAAAATAACATTACTAACAAACAACTTTTCAAATTAATGGAAGTTGAAAAAAGT
    TTAGTATACTTTTTAGCTGCCTTAAAAGGTAACGATACAATTATTAAAAAGTTATTCCGT
    TTACCTGCAATTAAACGTTTTGAAGAAGATGAAGAATTACTAGAAGATTTAATCATTGAA
    AATAACCAAGCCATCGAAACAACAGAATTACATCAACGTATCTTAGAAAGTATCACAACA
    TCATACGCTTCCTTATTATCTAATGATATGAATACGATTATGAAGACATTAACACTTTTC
    ACGGTACTATTAACGTTACCAACACTCGTATTTAGTTTCTTCGGTATGAATGTGCCGTTG
    CCAATTGATGACCATAGTTATATATCTTGGATTATTGTGGTAGGTATTTCATTAATTCTT
    GTCGTAATTGTTAGTATTTTCTTATGGCGTAAACAGAAATTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
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    660
    720
    780
    840
    900
    945

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS12470 [old locus tag: SACOL2375 ]
  • symbol: SACOL_RS12470
  • description: magnesium transporter CorA
  • length: 314
  • theoretical pI: 4.71169
  • theoretical MW: 36360.8
  • GRAVY: 0.038535

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsCations and iron carrying compoundsmagnesium and cobalt transport protein CorA (TIGR00383; HMM-score: 100.9)
  • TheSEED:
  • PFAM:
    no clan definedCorA; CorA-like Mg2+ transporter protein (PF01544; HMM-score: 198)
    DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 20.2)
    SIT; SHP2-interacting transmembrane adaptor protein, SIT (PF15330; HMM-score: 10.5)
    CPA_AT (CL0064) Mem_trans; Membrane transport protein (PF03547; HMM-score: 10.3)
    Tetraspannin (CL0347) CD20; CD20-like family (PF04103; HMM-score: 9.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.099
    • Ymax_pos: 69
    • Cmax: 0.106
    • Cmax_pos: 38
    • Smax: 0.112
    • Smax_pos: 39
    • Smean: 0.083
    • D: 0.093
  • predicted transmembrane helices (TMHMM): 2

Accession numbers[edit source | edit]

  • GI: 446555722 NCBI
  • RefSeq: WP_000633068 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MITSFRHSEDIDKHIIKTPLDHTASWINVVEPDREEIENLMEQYNIPEDFIRDPLDSEESSRIEYDEDTGYSLIIIDLPIVNSTNRSVLSFVTIPLGIIIGNGIIVTVCDAENEFLENLPKRDINLKFHSRFALEILTTIADHYNRNLRLLNKSRIRIEKELKNNITNKQLFKLMEVEKSLVYFLAALKGNDTIIKKLFRLPAIKRFEEDEELLEDLIIENNQAIETTELHQRILESITTSYASLLSNDMNTIMKTLTLFTVLLTLPTLVFSFFGMNVPLPIDDHSYISWIIVVGISLILVVIVSIFLWRKQKL

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS12470 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]