04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 02-MAR-2017
Contents
⊟Summary[edit source | edit]
- organism: Staphylococcus aureus COL
- locus tag: SACOL_RS14355
- pan locus tag?:
- symbol: SACOL_RS14355
- pan gene symbol?: —
- synonym:
- product: thiolase-like protein
⊟Genome View[edit source | edit]
⊟Gene[edit source | edit]
⊟General[edit source | edit]
- type: CDS
- locus tag: SACOL_RS14355
- symbol: SACOL_RS14355
- product: thiolase-like protein
- replicon: chromosome
- strand: +
- coordinates: 37063..37452
- length: 390
- essential: unknown
⊟Accession numbers[edit source | edit]
- Location: NC_002951 (37063..37452) NCBI
- MicrobesOnline:
⊟Phenotype[edit source | edit]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit source | edit]
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361ATTCAACTTTGCAACAGAACCGTATTATGGAATAGAGATGTTGGTAACATTTATACAGGA
TCATTATACTTAAGTTTAATTTCGTTATTACAGAACCACACATTCCAACCAGAAGAGAAA
GTATGTCTATTTAGTTATGGTTCAGGAGCAGTAGGAGAAATCTTTAGTGGTTCAATCGTT
AAAGGATATGACAAAGCATTAGATAAAGAGAAACACTTAAATATGCTAGAATCTAGAGAG
CAATTATCAGTCGAAGAATACGAAACATTCTTTAACAGATTTGATAATCAAGAATTTGAT
TTCGAACGTGAATTGACACAAGATCCATATTCAAAAGTATACTTATACAGTATAGAAGAC
CATATCAGAACATATAAGATAGAGAAATAA60
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⊟Protein[edit source | edit]
⊟General[edit source | edit]
- locus tag: SACOL_RS14355
- symbol: SACOL_RS14355
- description: thiolase-like protein
- length: 129
- theoretical pI: 4.67252
- theoretical MW: 15244
- GRAVY: -0.53876
⊟Function[edit source | edit]
- reaction:
- TIGRFAM: hydroxymethylglutaryl-CoA synthase (TIGR01835; EC 2.3.3.10; HMM-score: 115.5)hydroxymethylglutaryl-CoA synthase (TIGR01833; EC 2.3.3.10; HMM-score: 44.8)Fatty acid and phospholipid metabolismBiosynthesisputative hydroxymethylglutaryl-CoA synthase (TIGR00748; EC 2.3.3.10; HMM-score: 16.9)hopanoid biosynthesis associated membrane protein HpnM (TIGR03481; HMM-score: 11.2)
- TheSEED:
- PFAM: Thiolase (CL0046) HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal (PF08540; HMM-score: 50)ACP_syn_III_C; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal (PF08541; HMM-score: 17)tRNA_synt_II (CL0040) tRNA-synt_2e; Glycyl-tRNA synthetase alpha subunit (PF02091; HMM-score: 13.1)
⊟Structure, modifications & interactions[edit source | edit]
- domains:
- modifications:
- cofactors:
- effectors:
- protein partners:
⊟Localization[edit source | edit]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- Ymax: 0.191
- Ymax_pos: 38
- Cmax: 0.19
- Cmax_pos: 38
- Smax: 0.248
- Smax_pos: 34
- Smean: 0.141
- D: 0.171
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit source | edit]
- GI:
- RefSeq: WP_020444595 NCBI
- UniProt:
⊟Protein sequence[edit source | edit]
- MQLCNRTVLWNRDVGNIYTGSLYLSLISLLQNHTFQPEEKVCLFSYGSGAVGEIFSGSIVKGYDKALDKEKHLNMLESREQLSVEEYETFFNRFDNQEFDFERELTQDPYSKVYLYSIEDHIRTYKIEK
⊟Experimental data[edit source | edit]
- experimentally validated: no data available
⊟Expression & Regulation[edit source | edit]
⊟Operon[edit source | edit]
- SACOL_RS14355 no polycistronic organisation predicted
⊟Regulation[edit source | edit]
- sigma factor:
- regulator:
⊟Transcription pattern[edit source | edit]
- S.aureus Expression Data Browser: no data available
⊟Protein synthesis (provided by Aureolib)[edit source | edit]
- Aureolib: no data available
⊟Protein stability[edit source | edit]
- half-life: no data available
⊟Biological Material[edit source | edit]
⊟Mutants[edit source | edit]
⊟Expression vector[edit source | edit]
⊟lacZ fusion[edit source | edit]
⊟GFP fusion[edit source | edit]
⊟two-hybrid system[edit source | edit]
⊟FLAG-tag construct[edit source | edit]
⊟Antibody[edit source | edit]
⊟Other Information[edit source | edit]
You are kindly invited to share additional interesting facts.
⊟Literature[edit source | edit]
⊟References[edit source | edit]
⊟Relevant publications[edit source | edit]