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Summary[edit source | edit]

  • pan ID?: SAUPAN004221000
  • symbol?: mnmA
  • description?: tRNA-specific 2-thiouridylase MnmA

      descriptions from strain specific annotations:

    • tRNA-specific 2-thiouridylase MnmA
    • tRNA 2-thiouridine(34) synthase MnmA
    • tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase
    • 5-methylaminomethyl-2-thiouridylate- methyltransferase tRNA
    • tRNA methyl transferase
  • strand?: -
  • coordinates?: 4471865..4472638
  • synteny block?: BlockID0032490
  • occurrence?: in 100% of 32 strains

Orthologs[edit source | edit]

    COL:
    SACOL1676 (mnmA)
    N315:
    SA1449 (mnmA)
    NCTC8325:
    Newman:
    NWMN_1523 (mnmA)
    USA300_FPR3757:
    04-02981:
    SA2981_1579
    08BA02176:
    C248_1663
    11819-97:
    MS7_1637 (trmU)
    71193:
    ST398NM01_1685
    ECT-R 2:
    ECTR2_1470 (trmU)
    ED133:
    SAOV_1619 (trmU)
    ED98:
    SAAV_1614 (mnmA)
    HO 5096 0412:
    SAEMRSA15_15390
    JH1:
    SaurJH1_1712 (mnmA)
    JH9:
    SaurJH9_1679 (mnmA)
    JKD6008:
    SAA6008_01591 (trmU)
    JKD6159:
    SAA6159_01554 (trmU)
    LGA251:
    SARLGA251_15240
    M013:
    M013TW_1642
    MRSA252:
    SAR1701 (mnmA)
    MSHR1132:
    SAMSHR1132_14580
    MSSA476:
    SAS1557 (mnmA)
    Mu3:
    SAHV_1608 (mnmA)
    Mu50:
    SAV1621 (mnmA)
    MW2:
    MW1571 (mnmA)
    RF122:
    SAB1492c (mnmA)
    ST398:
    SAPIG1685 (trmU)
    T0131:
    SAT0131_01718
    TCH60:
    HMPREF0772_11520 (trmU)
    TW20:
    SATW20_16160
    USA300_TCH1516:
    USA300HOU_1621 (mnmA)
    VC40:
    SAVC_07355 (mnmA)

Genome Viewer[edit source | edit]

COL chromosome
N315 chromosome
NCTC8325 chromosome
Newman chromosome
USA300_FPR3757 chromosome

Alignments[edit source | edit]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.205)


    COL             MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIE
    N315            MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIE
    NCTC8325        MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIE
    Newman          MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIE
    USA300_FPR3757  -----------MSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIE
                               *************************************************

    COL             VCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGA
    N315            VCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGA
    NCTC8325        VCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKSLLDHAMNLGA
    Newman          VCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGA
    USA300_FPR3757  VCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGA
                    *************************************************::*********

    COL             DYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKSEVRR
    N315            DYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKSEVRR
    NCTC8325        DYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKSEVRR
    Newman          DYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKSEVRR
    USA300_FPR3757  DYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKSEVRR
                    ************************************************************

    COL             IAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTI
    N315            IAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTI
    NCTC8325        IAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTI
    Newman          IAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTI
    USA300_FPR3757  IAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTI
                    ************************************************************

    COL             GQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQ
    N315            GQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQ
    NCTC8325        GQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQ
    Newman          GQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQ
    USA300_FPR3757  GQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQ
                    ************************************************************

    COL             GFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDD
    N315            GFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDD
    NCTC8325        GFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDD
    Newman          GFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDD
    USA300_FPR3757  GFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDD
                    ************************************************************

    COL             VFKNEGQLNYVV
    N315            VFKNEGQLNYVV
    NCTC8325        VFKNEGQLNYVV
    Newman          VFKNEGQLNYVV
    USA300_FPR3757  VFKNEGQLNYVV
                    ************