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Summary[edit source | edit]

  • pan ID?: SAUPAN004239000
  • symbol?: relA
  • description?: GTP pyrophosphokinase

      descriptions from strain specific annotations:

    • GTP pyrophosphokinase
    • GTP pyrophosphokinase, (p)ppGpp synthetase I
    • GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase)(ppGpp synthetase I) ((p)ppGpp synthetase)
    • GTP pyrophosphokinase, (p)ppGpp synthetase I, RelA
    • GTP diphosphokinase
  • strand?: -
  • coordinates?: 4484268..4486457
  • synteny block?: BlockID0032670
  • occurrence?: in 100% of 32 strains

Orthologs[edit source | edit]

    COL:
    SACOL1689 (relA2)
    N315:
    SA1460 (relA)
    NCTC8325:
    Newman:
    NWMN_1536 (relA)
    USA300_FPR3757:
    04-02981:
    SA2981_1592 (relA)
    08BA02176:
    C248_1677 (relA)
    11819-97:
    MS7_1649 (relA)
    71193:
    ST398NM01_1697
    ECT-R 2:
    ECTR2_1482
    ED133:
    SAOV_1631 (relA)
    ED98:
    SAAV_1627 (relA2)
    HO 5096 0412:
    SAEMRSA15_15510 (relA)
    JH1:
    SaurJH1_1724
    JH9:
    SaurJH9_1691
    JKD6008:
    SAA6008_01603 (relA)
    JKD6159:
    SAA6159_01566 (relA)
    LGA251:
    SARLGA251_15360 (relA)
    M013:
    M013TW_1654
    MRSA252:
    SAR1714 (relA)
    MSHR1132:
    SAMSHR1132_14700
    MSSA476:
    SAS1570
    Mu3:
    SAHV_1621 (relA)
    Mu50:
    SAV1634 (relA)
    MW2:
    MW1584 (relA)
    RF122:
    SAB1503c (relA)
    ST398:
    SAPIG1697
    T0131:
    SAT0131_01733
    TCH60:
    HMPREF0772_11508 (relA)
    TW20:
    SATW20_16280 (relA)
    USA300_TCH1516:
    USA300HOU_1632 (relA2)
    VC40:
    SAVC_07415

Genome Viewer[edit source | edit]

COL chromosome
N315 chromosome
NCTC8325 chromosome
Newman chromosome
USA300_FPR3757 chromosome

Alignments[edit source | edit]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.205)


    COL             -------MNNEYPYSADEVLHKAKSYLSADEYEYVLKSYHIAYEAHKGQFRKNGLPYIMH
    N315            -------MNNEYPYSADEVLHKAKSYLSADEYEYVLKSYHIAYEAHKGQFRKNGLPYIMH
    NCTC8325        -------MNNEYPYSADEVLHKAKSYLSADEYEYVLKSYHIAYEAHKGQFRKNGLPYIMH
    Newman          MNGVYHIMNNEYPYSADEVLHKAKSYLSADEYEYVLKSYHIAYEAHKGQFRKNGLPYIMH
    USA300_FPR3757  MNGVYHIMNNEYPYSADEVLHKAKSYLSADEYEYVLKSYHIAYEAHKGQFRKNGLPYIMH
                           *****************************************************

    COL             PIQVAGILTEMRLDGPTIVAGFLHDVIEDTPYTFEDVKEMFNEEVARIVDGVTKLKKVKY
    N315            PIQVAGILTEMRLDGPTIVAGFLHDVIEDTPYTFEDVKEMFNEEVARIVDGVTKLKKVKY
    NCTC8325        PIQVAGILTEMRLDGPTIVAGFLHDVIEDTPYTFEDVKEMFNEEVARIVDGVTKLKKVKY
    Newman          PIQVAGILTEMRLDGPTIVAGFLHDVIEDTPYTFEDVKEMFNEEVARIVDGVTKLKKVKY
    USA300_FPR3757  PIQVAGILTEMRLDGPTIVAGFLHDVIEDTPYTFEDVKEMFNEEVARIVDGVTKLKKVKY
                    ************************************************************

    COL             RSKEEQQAENHRKLFIAIAKDVRVILVKLADRLHNMRTLKAMPREKQIRISRETLEIYAP
    N315            RSKEEQQAENHRKLFIAIAKDVRVILVKLADRLHNMRTLKAMPREKQIRISRETLEIYAP
    NCTC8325        RSKEEQQAENHRKLFIAIAKDVRVILVKLADRLHNMRTLKAMPREKQIRISRETLEIYAP
    Newman          RSKEEQQAENHRKLFIAIAKDVRVILVKLADRLHNMRTLKAMPREKQIRISRETLEIYAP
    USA300_FPR3757  RSKEEQQAENHRKLFIAIAKDVRVILVKLADRLHNMRTLKAMPREKQIRISRETLEIYAP
                    ************************************************************

    COL             LAHRLGINTIKWELEDTALRYIDNVQYFRIVNLMKKKRSEREAYIETAIDRIRTEMDRMN
    N315            LAHRLGINTIKWELEDTALRYIDNVQYFRIVNLMKKKRSEREAYIETAIDRIRTEMDRMN
    NCTC8325        LAHRLGINTIKWELEDTALRYIDNVQYFRIVNLMKKKRSEREAYIETAIDRIRTEMDRMN
    Newman          LAHRLGINTIKWELEDTALRYIDNVQYFRIVNLMKKKRSEREAYIETAIDRIRTEMDRMN
    USA300_FPR3757  LAHRLGINTIKWELEDTALRYIDNVQYFRIVNLMKKKRSEREAYIETAIDRIRTEMDRMN
                    ************************************************************

    COL             IEGDINGRPKHIYSIYRKMMKQKKQFDQIFDLLAIRVIVNSINDCYAILGLVHTLWKPMP
    N315            IEGDINGRPKHIYSIYRKMMKQKKQFDQIFDLLAIRVIVNSINDCYAILGLVHTLWKPMP
    NCTC8325        IEGDINGRPKHIYSIYRKMMKQKKQFDQIFDLLAIRVIVNSINDCYAILGLVHTLWKPMP
    Newman          IEGDINGRPKHIYSIYRKMMKQKKQFDQIFDLLAIRVIVNSINDCYAILGLVHTLWKPMP
    USA300_FPR3757  IEGDINGRPKHIYSIYRKMMKQKKQFDQIFDLLAIRVIVNSINDCYAILGLVHTLWKPMP
                    ************************************************************

    COL             GRFKDYIAMPKQNLYQSLHTTVVGPNGDPLEIQIRTFDMHEIAEHGVAAHWAYKEGKKVS
    N315            GRFKDYIAMPKQNLYQSLHTTVVGPNGDPLEIQIRTFDMHEIAEHGVAAHWAYKEGKKVS
    NCTC8325        GRFKDYIAMPKQNLYQSLHTTVVGPNGDPLEIQIRTFDMHEIAEHGVAAHWAYKEGKKVS
    Newman          GRFKDYIAMPKQNLYQSLHTTVVGPNGDPLEIQIRTFDMHEIAEHGVAAHWAYKEGKKVS
    USA300_FPR3757  GRFKDYIAMPKQNLYQSLHTTVVGPNGDPLEIQIRTFDMHEIAEHGVAAHWAYKEGKKVS
                    ************************************************************

    COL             EKDQTYQNKLNWLKELAEADHTSSDAQEFMETLKYDLQSDKVYAFTPASDVIELPYGAVP
    N315            EKDQTYQNKLNWLKELAEADHTSSDAQEFMETLKYDLQSDKVYAFTPASDVIELPYGAVP
    NCTC8325        EKDQTYQNKLNWLKELAEADHTSSDAQEFMETLKYDLQSDKVYAFTPASDVIELPYGAVP
    Newman          EKDQTYQNKLNWLKELAEADHTSSDAQEFMETLKYDLQSDKVYAFTPASDVIELPYGAVP
    USA300_FPR3757  EKDQTYQNKLNWLKELAEADHTSSDAQEFMETLKYDLQSDKVYAFTPASDVIELPYGAVP
                    ************************************************************

    COL             IDFAYAIHSEVGNKMIGAKVNGKIVPIDYILQTGDIVEIRTSKHSYGPSRDWLKIVKSSS
    N315            IDFAYAIHSEVGNKMIGAKVNGKIVPIDYILQTGDIVEIRTSKHSYGPSRDWLKIVKSSS
    NCTC8325        IDFAYAIHSEVGNKMIGAKVNGKIVPIDYILQTGDIVEIRTSKHSYGPSRDWLKIVKSSS
    Newman          IDFAYAIHSEVGNKMIGAKVNGKIVPIDYILQTGDIVEIRTSKHSYGPSRDWLKIVKSSS
    USA300_FPR3757  IDFAYAIHSEVGNKMIGAKVNGKIVPIDYILQTGDIVEIRTSKHSYGPSRDWLKIVKSSS
                    ************************************************************

    COL             AKGKIKSFFKKQDRSSNIEKGRMMVEAEIKEQGFRVEDILTEKNIQVVNEKYNFANEDDL
    N315            AKGKIKSFFKKQDRSSNIEKGRMMVEVEIKEQGFRVEDILTEKNIQVVNEKYNFANEDDL
    NCTC8325        AKGKIKSFFKKQDRSSNIEKGRMMVEAEIKEQGFRVEDILTEKNIQVVNEKYNFANEDDL
    Newman          AKGKIKSFFKKQDRSSNIEKGRMMVEAEIKEQGFRVEDILTEKNIQVVNEKYNFANEDDL
    USA300_FPR3757  AKGKIKSFFKKQDRSSNIEKGRMMVEAEIKEQGFRVEDILTEKNIQVVNEKYNFANEDDL
                    **************************.*********************************

    COL             FAAVGFGGVTSLQIVNKLTERQRILDKQRALNEAQEVTKSLPIKDNIITDSGVYVEGLEN
    N315            FAAVGFGGVTSLQIVNKLTERQRILDKQRALNEAQEVTKSLPIKDNIITDSGVYVEGLEN
    NCTC8325        FAAVGFGGVTSLQIVNKLTERQRILDKQRALNEAQEVTKSLPIKDNIITDSGVYVEGLEN
    Newman          FAAVGFGGVTSLQIVNKLTERQRILDKQRALNEAQEVTKSLPIKDNIITDSGVYVEGLEN
    USA300_FPR3757  FAAVGFGGVTSLQIVNKLTERQRILDKQRALNEAQEVTKSLPIKDNIITDSGVYVEGLEN
                    ************************************************************

    COL             VLIKLSKCCNPIPGDDIVGYITKGHGIKVHRTDCPNIKNETERLINVEWVKSKDATQKYQ
    N315            VLIKLSKCCNPIPGDDIVGYITKGHGIKVHRTDCPNIKNETERLINVEWVKSKDATQKYQ
    NCTC8325        VLIKLSKCCNPIPGDDIVGYITKGHGIKVHRTDCPNIKNETERLINVEWVKSKDATQKYQ
    Newman          VLIKLSKCCNPIPGDDIVGYITKGHGIKVHRTDCPNIKNETERLINVEWVKSKDATQKYQ
    USA300_FPR3757  VLIKLSKCCNPIPGDDIVGYITKGHGIKVHRTDCPNIKNETERLINVEWVKSKDATQKYQ
                    ************************************************************

    COL             VDLEVTAYDRNGLLNEVLQAVSSTAGNLIKVSGRSDIDKNAIINISVMVKNVNDVYRVVE
    N315            VDLEVTAYDRNGLLNEVLQAVSSTAGNLIKVSGRSDIDKNAIINISVMVKNVNDVYRVVE
    NCTC8325        VDLEVTAYDRNGLLNEVLQAVSSTAGNLIKVSGRSDIDKNAIINISVMVKNVNDVYRVVE
    Newman          VDLEVTAYDRNGLLNEVLQAVSSTAGNLIKVSGRSDIDKNAIINISVMVKNVNDVYRVVE
    USA300_FPR3757  VDLEVTAYDRNGLLNEVLQAVSSTAGNLIKVSGRSDIDKNAIINISVMVKNVNDVYRVVE
                    ************************************************************

    COL             KIKQLGDVYTVTRVWN
    N315            KIKQLGDVYTVTRVWN
    NCTC8325        KIKQLGDVYTVTRVWN
    Newman          KIKQLGDVYTVTRVWN
    USA300_FPR3757  KIKQLGDVYTVTRVWN
                    ****************