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NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_2069 [new locus tag: SAUSA300_RS11395 ]
  • pan locus tag?: SAUPAN005406000
  • symbol: SAUSA300_2069
  • pan gene symbol?: ptpB
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAUSA300_2069 [new locus tag: SAUSA300_RS11395 ]
  • symbol: SAUSA300_2069
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2231288..2231707
  • length: 420
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAAGATTTTATTCGTTTGTACAGGTAACACATGTCGTAGCCCATTAGCGGAAAGTATT
    GCAAAAGAGGTTATGCCAAATCATCAATTTGAATCAAGAGGTATATTCGCTGTGAACAAT
    CAAGGTGTTTCGAATTATGTTGAAGACTTAGTTGAAGAACATCATTTAGCTGAAACGACC
    TTATCGCAACAATTTACTGAAGCAGATTTGAAAGCAGATATTATTTTGACGATGTCGTAT
    TCGCACAAAGAATTAATAGAGGCACACTTTGGTTTGCAAAATCATGTTTTCACATTGCAT
    GAATATGTAAAAGAAGCAGGAGAAGTTATAGATCCATACGGTGGAACAAAAGAAATGTAT
    GTACATACCTATGAAGAACTTGTAAGTTTAATTTTAAAATTAAAAGATATTATTTGCTAG
    60
    120
    180
    240
    300
    360
    420

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAUSA300_2069 [new locus tag: SAUSA300_RS11395 ]
  • symbol: SAUSA300_2069
  • description: hypothetical protein
  • length: 139
  • theoretical pI: 4.81841
  • theoretical MW: 15787.9
  • GRAVY: -0.109353

Function[edit source | edit]

  • reaction:
    EC 3.1.3.48?  ExPASy
    Protein-tyrosine-phosphataseProtein tyrosine phosphate + H2O = protein tyrosine + phosphate
  • TIGRFAM:
    Cellular processesCellular processesDetoxificationarsenate reductase (thioredoxin) (TIGR02691; EC 1.20.4.-,3.1.3.48; HMM-score: 28.3)
    Cellular processesCellular processesDetoxificationarsenate reductase, glutathione/glutaredoxin type (TIGR02689; EC 1.20.4.1; HMM-score: 14.6)
  • TheSEED:  
    CBSS-176280.1.peg.1561 Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) 
    LMPTP YfkJ cluster Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) 
    LMPTP YwlE cluster Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) 
  • PFAM:
    Phosphatase (CL0031) LMWPc; Low molecular weight phosphotyrosine protein phosphatase (PF01451; HMM-score: 82.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.279
    • Ymax_pos: 22
    • Cmax: 0.17
    • Cmax_pos: 22
    • Smax: 0.575
    • Smax_pos: 16
    • Smean: 0.448
    • D: 0.345
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVSNYVEDLVEEHHLAETTLSQQFTEADLKADIILTMSYSHKELIEAHFGLQNHVFTLHEYVKEAGEVIDPYGGTKEMYVHTYEELVSLILKLKDIIC

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]