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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS13685 [old locus tag: SAUSA300_2468 ]
  • pan locus tag?: SAUPAN006179000
  • symbol: SAUSA300_RS13685
  • pan gene symbol?:
  • synonym:
  • product: N-acetyltransferase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAUSA300_RS13685 [old locus tag: SAUSA300_2468 ]
  • symbol: SAUSA300_RS13685
  • product: N-acetyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 2664128..2664619
  • length: 492
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_007793 (2664128..2664619) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGATTAGATACGCTAAAAAAGAGGATTTAAACGCTATATTAGCGATATACAATGATGCC
    ATTATCAATACTACAGCTGTTTATACTTATGAACCACAAACCATAGACGAACGTGTCGCA
    TGGTTTGAAACGAAACAACGTAAGCATGAGCCTATCTTTGTATTTGAGGAAAATGGAAGT
    GTCTTAGGGTTTGCGACGTTCGGTTCATTTAGACCTTGGCCAGCATACCTATATACAATC
    GAACATTCTATTTATGTCGATGCTTCAGCTAGAGGAAAAGGTATTGCTAGTCAATTACTA
    CACCATTTAATTGTGGAAGCAAAAGCTAAAGGTTATCGTGCGCTAGTTGCAGGCATTGAT
    GCTTCCAACAAAGCGAGTATTCAGTTGCATCAAAAGTTTGCTTTTAAGCATGCCGGCACA
    CTGACCAATGTAGGTTTTAAATTTAATAGATGGTTAGATTTAGCATTTTACGAATTAGAT
    TTACAAGACTAG
    60
    120
    180
    240
    300
    360
    420
    480
    492

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAUSA300_RS13685 [old locus tag: SAUSA300_2468 ]
  • symbol: SAUSA300_RS13685
  • description: N-acetyltransferase
  • length: 163
  • theoretical pI: 7.89534
  • theoretical MW: 18592
  • GRAVY: -0.149693

Function[edit source | edit]

  • reaction:
    EC 2.3.1.-?  ExPASy
  • TIGRFAM:
    Genetic information processingProtein synthesisRibosomal proteins: synthesis and modificationribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 36.3)
    Cellular processesCellular processesAdaptations to atypical conditionsdiaminobutyrate acetyltransferase (TIGR02406; EC 2.3.1.178; HMM-score: 31.5)
    UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 21.7)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersGlutathione and analogsmycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 12.8)
  • TheSEED:
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 81)
    Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 61.8)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 48.3)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 35.9)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 33.7)
    FR47; FR47-like protein (PF08445; HMM-score: 23.2)
    Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 22.9)
    GNAT_acetyltran; GNAT acetyltransferase (PF12746; HMM-score: 21.4)
    Acetyltransf_9; Acetyltransferase (GNAT) domain (PF13527; HMM-score: 19.4)
    Acetyltransf_13; ESCO1/2 acetyl-transferase (PF13880; HMM-score: 15)
    Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 12.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.122
    • Ymax_pos: 30
    • Cmax: 0.145
    • Cmax_pos: 30
    • Smax: 0.164
    • Smax_pos: 37
    • Smean: 0.096
    • D: 0.112
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446544581 NCBI
  • RefSeq: WP_000621927 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MIRYAKKEDLNAILAIYNDAIINTTAVYTYEPQTIDERVAWFETKQRKHEPIFVFEENGSVLGFATFGSFRPWPAYLYTIEHSIYVDASARGKGIASQLLHHLIVEAKAKGYRALVAGIDASNKASIQLHQKFAFKHAGTLTNVGFKFNRWLDLAFYELDLQD

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SAUSA300_RS13685 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]