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COLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS05885
  • pan locus tag?:
  • symbol: SA_RS05885
  • pan gene symbol?:
  • synonym:
  • product: S4 RNA-binding protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS05885
  • symbol: SA_RS05885
  • product: S4 RNA-binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1169642..1170448
  • length: 807
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_002745 (1169642..1170448) NCBI
  • BioCyc: G1G21-1186 BioCyc
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGGTATTTTATAATTTTTTTAAGGTAGTGATTAACATAGATATTTATCAACACTTTAGA
    CAGGAAGAATACGAATTAATTGATCAGCTAACGGATAAATGTGATCAAGCGGAACAACAT
    TATGCACCAGTATTAACGCATTTTTTAGATCCAAGAGGGCAATATATATTGGAAGTGATT
    TGTGGCAGTTATGAAGATTTAAACGTCTCTTTTTATGGCGGGCCTAATGCTGAAAGAAAA
    AGAGCAATCATTTCGCCGAACTATTATGAACCTAAAGAAAGTGACTTTGAATTAACTTTA
    ATGGAAATAGAGTATCCTGAAAAATTCGTCACTTTAAAACATCAACATATTTTAGGGACA
    TTAATGTCTTTAGGTATCGAACGCGAACAAGTTGGAGATATAATTGTGAATGAACGAATT
    CAATTTGTTTTGACAAGTAGATTGGAATCATTTATTATGTTAGAATTACAACGTATTAAA
    GGCGCATCAGTTAAACTTTATACTATTCCAGTAACAGATATGATACAATCTAATGAGAAT
    TGGAAAAATGAAAGTGCAACAGTTAGTTCTTTAAGGTTAGATGTTGTTATTAAAGAAATG
    ATACGTAAATCACGTACGATTGCGAAACAACTAATTGAAAAAAAACGTGTTAAAGTGAAT
    CACACTATTGTTGATTCAGCAGATTTTCAATTACAAGCAAATGATTTAATATCCATCCAA
    GGTTTTGGTAGAGCACACATTACTGACTTAGGTGGTAAAACTAAAAAAGATAAAACGCAC
    ATTACCTATAGAACATTATTCAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    807

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS05885
  • symbol: SA_RS05885
  • description: S4 RNA-binding protein
  • length: 268
  • theoretical pI: 6.72688
  • theoretical MW: 31214.7
  • GRAVY: -0.312313

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Photosynthesis photosystem II S4 domain protein (TIGR03069; HMM-score: 92.7)
    and 3 more
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal protein uS4 (TIGR01017; HMM-score: 25.8)
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase, RluA family (TIGR00005; EC 5.4.99.-; HMM-score: 15.4)
    Unknown function General TlyA family rRNA methyltransferase/putative hemolysin (TIGR00478; HMM-score: 15.2)
  • TheSEED:
  • PFAM:
    S4 (CL0492) S4; S4 domain (PF01479; HMM-score: 39.1)
    and 1 more
    no clan defined M11L; Apoptosis regulator M11L like (PF11099; HMM-score: 12.6)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004921
    • TAT(Tat/SPI): 0.000238
    • LIPO(Sec/SPII): 0.000493
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI: 446154656 NCBI
  • RefSeq: WP_000232511 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MVFYNFFKVVINIDIYQHFRQEEYELIDQLTDKCDQAEQHYAPVLTHFLDPRGQYILEVICGSYEDLNVSFYGGPNAERKRAIISPNYYEPKESDFELTLMEIEYPEKFVTLKHQHILGTLMSLGIEREQVGDIIVNERIQFVLTSRLESFIMLELQRIKGASVKLYTIPVTDMIQSNENWKNESATVSSLRLDVVIKEMIRKSRTIAKQLIEKKRVKVNHTIVDSADFQLQANDLISIQGFGRAHITDLGGKTKKDKTHITYRTLFK

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]