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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS05925 [old locus tag: SA1042 ]
  • pan locus tag?: SAUPAN003479000
  • symbol: SA_RS05925
  • pan gene symbol?: pyrP
  • synonym:
  • product: uracil permease

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA_RS05925 [old locus tag: SA1042 ]
  • symbol: SA_RS05925
  • product: uracil permease
  • replicon: chromosome
  • strand: +
  • coordinates: 1178528..1179835
  • length: 1308
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002745 (1178528..1179835) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
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    361
    421
    481
    541
    601
    661
    721
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    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGCAAAATGATGAAATGTTTGAACGAACAGTAAAACCAGTACTAGATGTAAATGAAAAA
    CCACAACCAGCGCAATGGGCATTTTTAAGCTTACAACATTTATTTGCGATGTTTGGCGCA
    ACAGTACTAGTACCATTCTTAACAGGACTACCAATATCCGCAGCGTTACTAGCTTCGGGA
    ATCGGTACATTACTTTATATCTTAATAACGAAGGCGCAAATACCAGCATACTTGGGATCT
    AGCTTTGCATTTATCACACCAATTATCACGGGATTAAGTACGCATAGCTTAGGAGACATG
    CTTGTAGCATTATTCATGAGTGGTGTTATGTACGTCATCATCGGAATTCTAATCAAATTA
    AGTGGGACAGCATGGTTAATGAAATTATTACCACCAGTTGTTGTTGGACCAGTCATCATG
    GTAATTGGTTTAAGCTTAGCGCCTACTGCAGTCAATATGGCAATGTATGAAAATCCTGGA
    GATATGAAAGGTTACAATATCAGTTTCTTAATTGTTGCAATGATAACCTTGCTTGTAACA
    ATAGTCGTTCAAGGATTTTTTAAAGGATTCCTATCTTTAATTCCAGTACTTGTAGGTATT
    ATCGTAGGTTATGTGGTAGCGATTTTTATGGGGATTGTGAAATTTGATGCAATTATGTCA
    GCAAAATGGATAGATTTCCCTCATATTTATCTGCCATTTAAAGATTATGTACCTTCATTT
    CACTTAGGACTTGTACTTGTAATGATTCCGATTGTGTTTGTAACAGTAAGTGAACATATT
    GGGCACCAAATGGTATTGAATAAAATCGTAGGTAGAAACTTCTTTGAAAAGCCAGGACTT
    GATAAATCAATCATTGGTGATGGTGTTTCTACAATGTTTGCCAGTATTATTGGTGGACCA
    CCAAGTACAACATACGGTGAAAATATCGGTGTATTAGCGATTACAAGAATATACAGTATT
    TACGTCATTGGTGGTGCAGCAGTTATAGCAATTGTTTTAGCATTCATTGGTAAGTTCACT
    GCATTAATTTCTTCTATACCTACACCAGTTATGGGAGGAGTATCTATATTACTTTTCGGT
    ATTATTGCAGCAAGTGGCTTAAGAATGTTAGTTGAAAGCAAAGTAGATTTTGCGAACAAT
    CGAAATTTAGTTATAGCTTCTGTAATTTTAGTTGTAGGTATCGGTAATTTAGTATTTAAC
    TTAAAAGAAATTGGTATCAACCTTCAAATTGAGGGGATGGCATTAGCTGCACTTTCAGGA
    ATTATTTTGAACTTAATCTTACCTAAAGAGAAAAAACAAAACAATTAA
    60
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    1308

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA_RS05925 [old locus tag: SA1042 ]
  • symbol: SA_RS05925
  • description: uracil permease
  • length: 435
  • theoretical pI: 9.31816
  • theoretical MW: 46609.9
  • GRAVY: 0.991724

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsNucleosides, purines and pyrimidinesuracil-xanthine permease (TIGR00801; HMM-score: 436.2)
    pyrimidine utilization transport protein G (TIGR03616; HMM-score: 277.1)
    xanthine permease (TIGR03173; HMM-score: 240.6)
  • TheSEED:
  • PFAM:
    APC (CL0062) Xan_ur_permease; Permease family (PF00860; HMM-score: 361.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.148
    • Ymax_pos: 55
    • Cmax: 0.216
    • Cmax_pos: 55
    • Smax: 0.162
    • Smax_pos: 46
    • Smean: 0.083
    • D: 0.123
  • predicted transmembrane helices (TMHMM): 11

Accession numbers[edit source | edit]

  • GI: 447101363 NCBI
  • RefSeq: WP_001178619 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MQNDEMFERTVKPVLDVNEKPQPAQWAFLSLQHLFAMFGATVLVPFLTGLPISAALLASGIGTLLYILITKAQIPAYLGSSFAFITPIITGLSTHSLGDMLVALFMSGVMYVIIGILIKLSGTAWLMKLLPPVVVGPVIMVIGLSLAPTAVNMAMYENPGDMKGYNISFLIVAMITLLVTIVVQGFFKGFLSLIPVLVGIIVGYVVAIFMGIVKFDAIMSAKWIDFPHIYLPFKDYVPSFHLGLVLVMIPIVFVTVSEHIGHQMVLNKIVGRNFFEKPGLDKSIIGDGVSTMFASIIGGPPSTTYGENIGVLAITRIYSIYVIGGAAVIAIVLAFIGKFTALISSIPTPVMGGVSILLFGIIAASGLRMLVESKVDFANNRNLVIASVILVVGIGNLVFNLKEIGINLQIEGMALAALSGIILNLILPKEKKQNN

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SA_RS05925 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]