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NCBI: 06-JUL-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1095 [new locus tag: NWMN_RS06205 ]
  • pan locus tag?: SAUPAN003455000
  • symbol: ftsA
  • pan gene symbol?: ftsA
  • synonym:
  • product: cell division protein FtsA

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_1095 [new locus tag: NWMN_RS06205 ]
  • symbol: ftsA
  • product: cell division protein FtsA
  • replicon: chromosome
  • strand: +
  • coordinates: 1200114..1201526
  • length: 1413
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGAAGAACATTACTACGTAAGTATTGATATTGGATCATCAAGCGTAAAAACAATAGTA
    GGCGAGAAATTTCACAATGGTATAAATGTGATAGGTACAGGACAAACCTACACGAGCGGT
    ATAAAAAATGGTTTAATTGATGATTTTGATATTGCGCGACAAGCAATCAAAGACACAATT
    AAAAAGGCATCAATCGCTTCGGGTGTTGATATTAAAGAAGTTTTCCTGAAATTACCTATC
    ATTGGAACGGAAGTTTATGATGAATCAAATGAAATCGACTTTTATGAGGATACAGAAATC
    AACGGTTCACATATCGAAAAAGTATTAGAAGGTATTAGAGAAAAAAATGATGTGCAAGAA
    ACAGAAGTAATTAATGTGTTCCCGATTCGTTTTATAGTCGATAAAGAAAATGAGGTTTCA
    GACCCTAAAGAATTAATTGCCAGACATTCATTAAAGGTTGAAGCAGGCGTAATTGCTATT
    CAAAAATCGATTTTAATTAATATGATTAAATGCGTAGAAGCATGTGGTGTTGATGTATTA
    GATGTTTACTCTGATGCATATAACTATGGTTCAATCCTAACAGCTACTGAAAAAGAGTTA
    GGTGCATGTGTCATTGATATTGGTGAAGACGTTACGCAAGTTGCTTTTTATGAACGCGGT
    GAATTAGTAGATGCTGATTCTATCGAAATGGCAGGGCGTGATATTACAGACGATATTGCA
    CAAGGATTAAACACTTCTTATGAAACTGCTGAAAAAGTTAAACACCAATATGGTCATGCA
    TTCTATGATTCTGCTTCAGATCAAGATATCTTCACTGTTGAACAGGTTGATAGTGATGAA
    ACAGTACAGTATACTCAAAAAGATTTGAGTGACTTTATTGAAGCGCGTGTAGAAGAAATA
    TTCTTCGAAGTATTTGATGTTTTACAAGATTTAGGATTAACAAAAGTAAATGGTGGGTTT
    ATTGTAACTGGTGGATCTGCAAACTTACTTGGCGTAAAAGAATTATTATCAGATATGGTA
    AGTGAAAAAGTTAGAATTCACACGCCATCACAAATGGGAATTAGAAAACCTGAATTTTCT
    TCAGCAATTTCTACAATTTCTAGTAGTATCGCTTTTGATGAGTTATTAGATTATGTTACA
    ATTAATTATCATGATAATGAAGAAACTGAAGAAGATGTTATTGATGTGAAAGACAAAGAT
    AACGAATCTAAATTAGGCGGATTTGATTGGTTTAAACGTAAAACAAACAAAAAAGATACT
    CATGAAAATGAAGTAGAGTCAACAGATGAAGAAATTTATCAATCAGAAGATAATCATCAG
    GAACATAAACAGAATCATGAACATGTTCAAGACAAAGATAAAGATAAAGAAGAAAGTAAA
    TTCAAAAAACTAATGAAATCTCTATTTGAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1413

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_1095 [new locus tag: NWMN_RS06205 ]
  • symbol: FtsA
  • description: cell division protein FtsA
  • length: 470
  • theoretical pI: 4.21772
  • theoretical MW: 52934.3
  • GRAVY: -0.464468

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Cell division cell division protein FtsA (TIGR01174; HMM-score: 273.4)
    and 3 more
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan cell shape determining protein, MreB/Mrl family (TIGR00904; HMM-score: 39.7)
    type IV pilus assembly protein PilM (TIGR01175; HMM-score: 28.7)
    ethanolamine utilization protein EutJ family protein (TIGR02529; HMM-score: 20.1)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    Actin_ATPase (CL0108) FtsA; Cell division protein FtsA (PF14450; HMM-score: 90.5)
    and 6 more
    MreB_Mbl; MreB/Mbl protein (PF06723; HMM-score: 55.2)
    SHS2 (CL0319) SHS2_FTSA; SHS2 domain inserted in FTSA (PF02491; HMM-score: 42.6)
    Actin_ATPase (CL0108) PilM_2; Type IV pilus assembly protein PilM; (PF11104; HMM-score: 28.3)
    no clan defined DUF2410; Hypothetical protein (DUF2410) (PF10307; HMM-score: 18.2)
    Actin_ATPase (CL0108) BcrAD_BadFG; BadF/BadG/BcrA/BcrD ATPase family (PF01869; HMM-score: 17.3)
    no clan defined BDM; Putative biofilm-dependent modulation protein (PF10684; HMM-score: 15.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.043327
    • TAT(Tat/SPI): 0.000349
    • LIPO(Sec/SPII): 0.001222
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MEEHYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREKNDVQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLDYVTINYHDNEETEEDVIDVKDKDNESKLGGFDWFKRKTNKKDTHENEVESTDEEIYQSEDNHQEHKQNHEHVQDKDKDKEESKFKKLMKSLFE

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]