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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0233 [new locus tag: SA_RS01375 ]
  • pan locus tag?: SAUPAN001110000
  • symbol: SA0233
  • pan gene symbol?: glcC
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA0233 [new locus tag: SA_RS01375 ]
  • symbol: SA0233
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 282604..284133
  • length: 1530
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGAAATCTTTATTTGAAAAAGCACAGCAGTTCGGCAAGTCCTTTATGTTACCTATCGCA
    ATCTTACCAGCTGCAGGTCTATTGTTGGGTATCGGTGGTGCATTAAGTAATCCAAACACC
    GTTAAAGCATACCCTATTTTAGATATTACCTTATTACAAAATATTTTTACATTAATGTCA
    GCTGCAGGTAGTATTGTTTTCCAAAATTTACCGGTCATCTTTGCAATTGGTGTCGCAATC
    GGATTATCTAGAAGCGATAAAGGTACTGCAGGTTTAGCTGCGCTGCTCGGTTTCTTAATT
    ATGAACGCAACTATGAATGGCTTATTAACTATCACGGGCACATTGGCAAAAGATCAGCTT
    GCACAAAATGGACAAGGCATGGTGCTCGGTATACAAACGGTTGAAACCGGTGTTTTTGGC
    GGGATTATCACAGGTATTATGACCGCAATACTTCACAACAAATATCACAAAGTGGTATTA
    CCACCGTATTTAGGTTTCTTTGGTGGCTCTAGATTTGTCCCTATTGTCACAGCATTTGCC
    GCAATCTTTTTAGGTGTATTGATGTTTTTCATTTGGCCAAGCATACAAGCCGGCATTTAT
    CATGTTGGTGGATTTGTAACGAAAACAGGTGCCATCGGTACTTTTGTTTATGGCTTCATC
    TTAAGATTGTTAGGTCCACTCGGTTTACACCATATTTTTTACTTACCGTTTTGGCAGACG
    GCACTTGGTGGTACTTTAGAAGTCAAAGGGCACTTAGTTCAAGGTACGCAGAACATCTTC
    TTTGCTCAACTTGGTGATCCAGATGTGACGAAGTATTATTCAGGTGTGTCACGCTTTATG
    TCAGGCCGTTTTATTACGATGATGTTCGGCTTATGTGGTGCCGCACTTGCAATTTATCAC
    ACAGCTAAACCTGAACATAAAAAAGTTGTCGGCGGTTTAATGTTATCCGCTGCACTCACT
    TCATTTTTAACAGGTATTACCGAACCTTTAGAGTTTAGTTTCTTGTTTGTCGCACCTATT
    CTTTATGTAATCCATGCCTTCTTTGATGGATTAGCATTTATGATGGCAGACATTTTCAAC
    ATTACAATTGGTCAAACCTTCAGTGGAGGCTTTATCGATTTCTTACTCTTTGGTGTGCTA
    CAAGGTAATAGTAAAACAAACTACCTATACGTCATACCTATTGGAATTGTGTGGTTCTGT
    TTGTATTACATCGTTTTCAGATTCTTAATTACGAAATTTAATTTCAAAACACCTGGTCGA
    GAAGATAAAGCTGCAGCACAACAAGTTGAGGCTACTGAAAGAGCACAAACTATTGTTGCT
    GGTTTGGGAGGCAAAGATAACATTGAAATCGTTGACTGTTGTGCAACGAGACTACGCGTC
    ACACTTAATCAAAATGACAAAGTCGATAAAGTATTACTCGAAAGTACTGGTGCCAAAGGT
    GTAATCCAGCAAGGCACTGGTGTGCAAGTAATTTATGGGCCTCACGTTACAGTTATCAAA
    AATGAAATTGAAGAATTGCTCGGGGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1530

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA0233 [new locus tag: SA_RS01375 ]
  • symbol: SA0233
  • description: hypothetical protein
  • length: 509
  • theoretical pI: 8.96467
  • theoretical MW: 54910.3
  • GRAVY: 0.612967

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-specific IIBC component (TIGR02002; EC 2.7.1.69; HMM-score: 592.3)
    and 11 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific IIBC component (TIGR02004; EC 2.7.1.69; HMM-score: 464.9)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, N-acetylglucosamine-specific IIBC component (TIGR01998; EC 2.7.1.69; HMM-score: 450.2)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, alpha-glucoside-specific IIBC component (TIGR02005; EC 2.7.1.69; HMM-score: 312.7)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 285.1)
    Signal transduction Signal transduction PTS PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 285.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, IIBC component (TIGR02003; EC 2.7.1.69; HMM-score: 268.2)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 72.4)
    Signal transduction Signal transduction PTS PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 72.4)
    PTS system, sucrose-specific IIBC component (TIGR01996; EC 2.7.1.69; HMM-score: 70.3)
    PTS system, beta-glucoside-specific IIABC component (TIGR01995; EC 2.7.1.69; HMM-score: 44.7)
    PTS system, trehalose-specific IIBC component (TIGR01992; EC 2.7.1.69; HMM-score: 44.3)
  • TheSEED  :
    • PTS system, N-acetylmannosamine-specific IIB component
    • PTS system, N-acetylmannosamine-specific IIC component
    Carbohydrates Di- and oligosaccharides Maltose and Maltodextrin Utilization  PTS system, maltose and glucose-specific IIB component (EC 2.7.1.69)
    and 1 more
    Carbohydrates Di- and oligosaccharides Maltose and Maltodextrin Utilization  PTS system, maltose and glucose-specific IIC component (EC 2.7.1.69)
  • PFAM:
    PTS_EIIC (CL0493) PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 312)
    and 1 more
    no clan defined PTS_EIIB; phosphotransferase system, EIIB (PF00367; HMM-score: 49.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: Signal peptide SP(Sec/SPI) length 43 aa
    • SP(Sec/SPI): 0.578981
    • TAT(Tat/SPI): 0.088154
    • LIPO(Sec/SPII): 0.051874
    • Cleavage Site: CS pos: 43-44. VKA-YP. Pr: 0.4433
  • predicted transmembrane helices (TMHMM): 11

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKSLFEKAQQFGKSFMLPIAILPAAGLLLGIGGALSNPNTVKAYPILDITLLQNIFTLMSAAGSIVFQNLPVIFAIGVAIGLSRSDKGTAGLAALLGFLIMNATMNGLLTITGTLAKDQLAQNGQGMVLGIQTVETGVFGGIITGIMTAILHNKYHKVVLPPYLGFFGGSRFVPIVTAFAAIFLGVLMFFIWPSIQAGIYHVGGFVTKTGAIGTFVYGFILRLLGPLGLHHIFYLPFWQTALGGTLEVKGHLVQGTQNIFFAQLGDPDVTKYYSGVSRFMSGRFITMMFGLCGAALAIYHTAKPEHKKVVGGLMLSAALTSFLTGITEPLEFSFLFVAPILYVIHAFFDGLAFMMADIFNITIGQTFSGGFIDFLLFGVLQGNSKTNYLYVIPIGIVWFCLYYIVFRFLITKFNFKTPGREDKAAAQQVEATERAQTIVAGLGGKDNIEIVDCCATRLRVTLNQNDKVDKVLLESTGAKGVIQQGTGVQVIYGPHVTVIKNEIEELLGD

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]