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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0263 [new locus tag: SA_RS01550 ]
  • pan locus tag?: SAUPAN001161000
  • symbol: SA0263
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA0263 [new locus tag: SA_RS01550 ]
  • symbol: SA0263
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 317324..318700
  • length: 1377
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    GTGAATAACACACAATCTTCACCACGCAGTAATATTATTATTGCGATTATGTTGTCTGCA
    TTAACATATTGGTTGTTTGCACAATCATTTATTAATATAGGACCTCTCGTTGGTCAAACG
    TATCAAACCTCTCCTGCCGTGTTAAATTTATCTATTAGTTTAACTTCCTTCGCCACAGGT
    ATCTTCATGGTGGCTGCAGGTGATATTGCTGATAAAATAGGACAACTGAGAATGACATAC
    ATGGGTCTCATAATCAGTATGTTTGCATCTCTTCTATTAATTATATCGGACATCACTGCA
    CTGCTCATCATCGGTAGAATTTTACAAGGTCTATCAGCAGCTATCTTGTTACCTTCAACA
    GTTGGCGTTTTAAATAATCAATTTAAAGGAGAACATTTAAGACGAGCGATTAGTTATCTA
    ATGATTAGTACTGTTGGGGGCATCGGCCTAGCTGGTGTTATCGGCGGTTTAATTGCTACA
    AATTTCGGATGGCAAATGAATTTCATCATTAGTATAGTCATTGCTTTCATTGCCATATTA
    CTTCTAAAAGGCACACCTGAAAAAGTAAGTCAACATAGCCACCGTCATCCGTTCGATTAC
    AAAGGTATGTCGATTTTCGCTGTTATGATTGGTAGCTTTACATTATTGTTAACACAAGGA
    TTCGAACAAGGTTGGTTTAGTACATTCTCATTCATTTGTCTGAGCATTTTTATCATCACT
    ACGCTGATATTCATCATCATCGAACGTCGACATGAAGTACCTTTTATTGATTTCTCAGTA
    TTACGCAACCGTCCGTTCATTGGTGCATTTTTAAATAACTTTGTTTTAAATAGCGGTCTA
    GGCGTTACAGTGGTCTTTTTCATATATGCTCAAACACACCTTGGTTTATCAGCTGCGCAA
    TCTGGACTTGTTACATTGCCATATGCCATTGTGGCAGTTGCGATGATTCGTTTAGGTGAA
    AAAGCAACATTACGTTTCGGTGGCAAATTGATGCTCATCATTGGTCCGTTGTTCCCTGTC
    ATCGGCATCACTATTATTAGCATGACTCAATTATCGGCATCACAATATGTCATTGCAGTT
    ATCATTGGTTTCGTCATTTGCGCAATTGGAAATGGTTTAGTCGCAACACCCGGCCTTACA
    ATTGCAATTTTCAGTATGCCAAATGAAAAAGTTGGTTTAGCTACAGGATTATATAAAATG
    AGTGGTACATTAGGTGGCGCCTTTGGTATAGCACTAAGTACTACAGTTTTCAGTATGTTA
    CAACTAAACTATGCACCAAGTGTAGCTGCAACCGTAACATTTATCGTCAGCATTGTATTG
    ATGATCCTTGGCTCATTGTCTGCATACATGATCATTCCAAAAACAGTTAAATCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1377

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA0263 [new locus tag: SA_RS01550 ]
  • symbol: SA0263
  • description: hypothetical protein
  • length: 458
  • theoretical pI: 10.1683
  • theoretical MW: 49092.4
  • GRAVY: 0.972707

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Toxin production and resistance drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 129.9)
    Metabolism Transport and binding proteins Other drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 129.9)
    and 8 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 58.2)
    multidrug resistance protein (TIGR00880; HMM-score: 46.9)
    drug resistance transporter, Bcr/CflA subfamily (TIGR00710; HMM-score: 41)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, aromatic acid:H+ symporter (AAHS) family (TIGR00895; HMM-score: 33.5)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids phosphoglycerate transporter family protein (TIGR00881; HMM-score: 29.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids oxalate/formate antiporter family transporter (TIGR00890; HMM-score: 20.1)
    Metabolism Transport and binding proteins Unknown substrate MFS transporter, metabolite:H+ symporter (MHS) family protein (TIGR00883; HMM-score: 19)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids sugar efflux transporter (TIGR00899; HMM-score: 16.8)
  • TheSEED  :
    • Uncharacterized MFS-type transporter
  • PFAM:
    MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 137.3)
    and 1 more
    no clan defined UL42; HCMV UL42 (PF17638; HMM-score: 12.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 14
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0.5
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.123294
    • TAT(Tat/SPI): 0.003305
    • LIPO(Sec/SPII): 0.01869
  • predicted transmembrane helices (TMHMM): 14

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTSPAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALLIIGRILQGLSAAILLPSTVGVLNNQFKGEHLRRAISYLMISTVGGIGLAGVIGGLIATNFGWQMNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLTQGFEQGWFSTFSFICLSIFIITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVLNSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLIIGPLFPVIGITIISMTQLSASQYVIAVIIGFVICAIGNGLVATPGLTIAIFSMPNEKVGLATGLYKMSGTLGGAFGIALSTTVFSMLQLNYAPSVAATVTFIVSIVLMILGSLSAYMIIPKTVKS

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]