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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0463 [new locus tag: SA_RS02670 ]
  • pan locus tag?: SAUPAN002246000
  • symbol: SA0463
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA0463 [new locus tag: SA_RS02670 ]
  • symbol: SA0463
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 536239..537432
  • length: 1194
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGCACATACCATTACGATTGTTGGCTTAGGAAACTATGGCATTGATGATTTGCCGCTA
    GGGATATATAAATTTTTAAAGACACAAGATAAAGTTTATGCAAGAACGTTAGATCATCCA
    GTTATAGAATCATTGCAAGATGAATTAACATTTCAGAGTTTTGACCATGTTTATGAAGCA
    CATGACCAATTTGAAGATGTCTATAACGATATTGTGGCGCAATTGGTTGAAGCTGCTAAT
    GAAAAAGATATTGTCTATGCGGTTCCGGGTCATCCTAGAGTTGCTGAGACAACTACAGTG
    AAATTACTGGCTTTAGCAAAGGACAATACTGATATAGATGTGAAAGTTTTAGGTGGTAAA
    AGCTTTATTGATGATGTGTTTGAAGCAGTTAATGTAGATCCAAATGATGGCTTCACACTG
    TTAGATGCGACATCATTACAAGAAGTAATACTTAATGTTAGAACGCATACATTGATTACG
    CAAGTTTATAGTGCAATGGTTGCTGCTAATTTGAAAATCACTTTAATGGAACGATATCCT
    GATGATTACCCTGTTCAAATTGTCACTGGTGCACGAAGCGATGGTGCGGATAACGTTGTG
    ACATGCCCATTATATGAATTGGATCATGATGAAAATGCATTCAATAATTTGACGAGTGTA
    TTCGTACCAAAAATCATAACATCGACATATTTGTATCATGACTTTGATTTTGCAACGGAA
    GTGATTGATACTTTAGTTGATGAAGATAAAGGTTGTCCATGGGATAAAGTGCAAACGCAT
    GAAACGCTTAAGCGTTATTTACTTGAAGAAACATTTGAATTGTTCGAAGCTATTGACAAT
    GAAGATGATTGGCATATGATTGAAGAACTAGGAGATATTTTATTACAAGTGTTATTGCAT
    ACTAGTATTGGTAAAAAAGAAGGGTATATCGACATTAAAGAAGTGATTACAAGTCTTAAT
    GCTAAAATGATTCGTAGACACCCACACATATTTGGTGATGCCAATGCTGAAACTATCGAT
    GACTTAAAAGAAATTTGGTCTAAGGCGAAAGATGCTGAAGGTAAACAGCCAAGAGTTAAA
    TTTGAAAAAGTATTTGCAGAGCATTTTTTAAATTTATATGAGAAGACGAAGGATAAGTCA
    TTTGATGAGGCCTCGTTAAAGCAGTGGCTAGAAAAAGGGGAGAGTAATACATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1194

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA0463 [new locus tag: SA_RS02670 ]
  • symbol: SA0463
  • description: hypothetical protein
  • length: 397
  • theoretical pI: 4.34085
  • theoretical MW: 45139.4
  • GRAVY: -0.288413

Function[edit | edit source]

  • TIGRFAM:
    Unknown function General MazG family protein (TIGR00444; HMM-score: 132.4)
    and 2 more
    Genetic information processing Protein fate Protein modification and repair diphthine synthase (TIGR00522; EC 2.1.1.98; HMM-score: 31)
    Unknown function Enzymes of unknown specificity encapsulated protein (TIGR04536; HMM-score: 12.9)
  • TheSEED  :
    • Nucleoside triphosphate pyrophosphohydrolase MazG (EC 3.6.1.8)
    Nucleosides and Nucleotides Detoxification Nucleoside triphosphate pyrophosphohydrolase MazG  Nucleoside triphosphate pyrophosphohydrolase MazG (EC 3.6.1.8)
    and 1 more
    Nucleosides and Nucleotides Detoxification Nucleoside triphosphate pyrophosphohydrolase MazG  possible tetrapyrrole methyltransferase domain
  • PFAM:
    MazG (CL0231) MazG; MazG nucleotide pyrophosphohydrolase domain (PF03819; HMM-score: 93.4)
    and 2 more
    no clan defined TP_methylase; Tetrapyrrole (Corrin/Porphyrin) Methylases (PF00590; HMM-score: 71.3)
    MazG (CL0231) MazG-like; MazG-like family (PF12643; HMM-score: 13)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002807
    • TAT(Tat/SPI): 0.000101
    • LIPO(Sec/SPII): 0.000241
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MAHTITIVGLGNYGIDDLPLGIYKFLKTQDKVYARTLDHPVIESLQDELTFQSFDHVYEAHDQFEDVYNDIVAQLVEAANEKDIVYAVPGHPRVAETTTVKLLALAKDNTDIDVKVLGGKSFIDDVFEAVNVDPNDGFTLLDATSLQEVILNVRTHTLITQVYSAMVAANLKITLMERYPDDYPVQIVTGARSDGADNVVTCPLYELDHDENAFNNLTSVFVPKIITSTYLYHDFDFATEVIDTLVDEDKGCPWDKVQTHETLKRYLLEETFELFEAIDNEDDWHMIEELGDILLQVLLHTSIGKKEGYIDIKEVITSLNAKMIRRHPHIFGDANAETIDDLKEIWSKAKDAEGKQPRVKFEKVFAEHFLNLYEKTKDKSFDEASLKQWLEKGESNT

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]