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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0745 [new locus tag: SA_RS04240 ]
  • pan locus tag?: SAUPAN002797000
  • symbol: SA0745
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA0745 [new locus tag: SA_RS04240 ]
  • symbol: SA0745
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 854886..855407
  • length: 522
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAAAAGGAAAGTACTAGTACTAACAATGGGTGTAATTTGTGCAACTCAATTATGGCAT
    TCTAATCACGCAAACGCATTAGTGACAGAGAGTGTTGAAACTAATTTTGTTGTAAAAGAT
    TCGGATAATAAAAATATTTTACAAACCCATACTGAAATTACTACTGAGGAGAAATTTTCA
    ATAGTAGAAAAGAGTCAATTAAATAAATTAAAAGCACTATCTAATGACAACTACATAGAA
    TATGATTTACATACTAATCAAACAGGTATTAAAAAAGGTTGGTTATATGGTTATAGTGAA
    ATTGACTCATCACATTTCACAGACCGTGACAAACGCGTTATTAGACGTGATCATGTTAAA
    GAAGCACAAAGCTTAATTAACGATTATAAAGATACACAAAGCTATGAAGATCTCGCTAAG
    GCAACTGCAAAAGTAAGTACACTTAGTCAGTCTCACCAAAATTATTTAAATAAACAAATT
    GATAAAGTGAATAATAAAATAGAGAAAACTGAAAAACGCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    522

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA0745 [new locus tag: SA_RS04240 ]
  • symbol: SA0745
  • description: hypothetical protein
  • length: 173
  • theoretical pI: 8.89242
  • theoretical MW: 20032.3
  • GRAVY: -0.831792

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Transcription DNA-dependent RNA polymerase DNA-directed RNA polymerase delta subunit (TIGR04567; EC 2.7.7.6; HMM-score: 13.3)
  • TheSEED  :
    • Hypothetical protein, similarity with von Willebrand factor-binding VWbp
    Virulence, Disease and Defense Adhesion Adhesins in Staphylococcus  Hypothetical protein, similarity with von Willebrand factor-binding VWbp
  • PFAM:

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.21
    • Extracellular Score: 0.78
    • Internal Helices: 0
  • LocateP: N-terminally anchored (No CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: -0.17
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: 2
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: Signal peptide SP(Sec/SPI) length 26 aa
    • SP(Sec/SPI): 0.991829
    • TAT(Tat/SPI): 0.001302
    • LIPO(Sec/SPII): 0.002335
    • Cleavage Site: CS pos: 26-27. ANA-LV. Pr: 0.9337
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKRKVLVLTMGVICATQLWHSNHANALVTESVETNFVVKDSDNKNILQTHTEITTEEKFSIVEKSQLNKLKALSNDNYIEYDLHTNQTGIKKGWLYGYSEIDSSHFTDRDKRVIRRDHVKEAQSLINDYKDTQSYEDLAKATAKVSTLSQSHQNYLNKQIDKVNNKIEKTEKR

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]