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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA2156 [new locus tag: SA_RS12380 ]
  • pan locus tag?: SAUPAN005878000
  • symbol: SA2156
  • pan gene symbol?: lctP2
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA2156 [new locus tag: SA_RS12380 ]
  • symbol: SA2156
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2421937..2423535
  • length: 1599
  • essential: yes DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGTTAGTAAATACGTTTAACCCATTTGATAATTTATTATTATCGTCTTTAATTGCAGCA
    ATACCGATTGTACTGTTTTTACTATGTTTAACTGTTTTTAAAATGAAAGGTATTTATGCA
    GCTATTACAACACTTGTTGTAACATTACTAATTGCAATACCATTTTTCAAATTGCCAGTT
    GGTATCGCTTCTGGTGCAGTAGTCGAAGGTTTCTTCCAAGGTATCATTCCGATTGGCTAT
    ATCGTTATGATGGCAGTATTGTTATACAAAATTACTGTTGAATCTGGACAATTTTTAACA
    ATTCAAGATAGTATTACAAATATTTCACAAGACCAACGTATTCAAGTTTTACTTATTGGA
    TTTGCATTCAACGCATTTTTAGAAGGTGCAGCAGGATTTGGTGTACCAATTGCAATTTGT
    GCACTTTTATTAACACAATTAGGATTTAATCCATTAAAAGCTGCGATGTTATGTTTAGTC
    GCAAATGCAGCGTCTGGTGCTTTTGGTGCGATTGGTATCCCTGTAGGTGTTGTAGAAACG
    TTGAAATTACCTGGAGATGTTTCAGTATTAGGTGTTTCTCAATCAGCAACTTTAACATTG
    GCAATCATAAATTTCATTATTCCATTCTTACTTATCTTTATTATTGATGGTTTTAGAGGT
    GTTAAAGAAACATTACCAGCAATTTTAGTAGTTTCAATCACTTATACACTTACTCAAGGA
    TTATTAACTGTATTCAGTGGACCTGAATTAGCAGATATTATTCCACCGTTATTAACAATG
    TTAGCATTAGCAGTATTTTCTAAAAAATTCCAACCAAAACACATTTATCGTGTTAATAAA
    GATGAAGAAATTGAACCTGCAAAAGCACATTCTGCAAAAGCAGTATTACATGCATGGAGC
    CCATTCATTGTATTAACAGTCATTGTAATGATTTGGAGTGCGCCATTCTTTAAAAACTTA
    TTCTTACCAAATGGTGCTTTATCATCATTAGTATTTAAATTCAACTTACCTGGAACAATC
    AGCGAAGTTACGCATAAACCATTAGTATTGACTTTAAATATTATTGGACAAACAGGTACA
    GCTATTTTATTAACTATTATTATTACAATTTTAATGTCTAAAAAGGTTAACTTTAAAGAT
    GCTGTTAGATTATTCGGCGTTACATTTAAAGAGTTGTGGTTACCAGTTCTTACAATTTGT
    TTCATCTTAGCAATCTCTAAAATCACAACTTATGGTGGTTTAAGTGCAGCAATGGGTCAA
    GGTATAGCTAAAGCAGGTAATGTCTTCCCAGTTCTATCACCAATCTTAGGTTGGATAGGT
    GTGTTTATGACAGGATCAGTTGTAAATAACAATTCATTATTTGCACCAATTCAAGCTTCT
    GTTGCACAACAAATTGGAACAAGTGGTTCACTTCTTGTATCTGCTAATACAGTTGGTGGT
    GTAGCGGCAAAATTGATTTCACCACAATCAATTGCAATTGCAACTGCAGCAGTAAAACAA
    GTTGGTAAGGAATCAGAATTATTAAAAATGACATTGAAATACAGTGTATGTTTACTAATA
    TTCATCTGTATTTGGACTTTCATCTTGTCATTATTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1599

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA2156 [new locus tag: SA_RS12380 ]
  • symbol: SA2156
  • description: hypothetical protein
  • length: 532
  • theoretical pI: 9.63197
  • theoretical MW: 56683.9
  • GRAVY: 1.02575

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids transporter, lactate permease (LctP) family (TIGR00795; HMM-score: 529.2)
  • TheSEED  :
    • L-lactate permease
  • PFAM:
    IT (CL0182) Lactate_perm; L-lactate permease (PF02652; HMM-score: 534.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 13
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0.5
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002225
    • TAT(Tat/SPI): 0.000303
    • LIPO(Sec/SPII): 0.002796
  • predicted transmembrane helices (TMHMM): 13

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MLVNTFNPFDNLLLSSLIAAIPIVLFLLCLTVFKMKGIYAAITTLVVTLLIAIPFFKLPVGIASGAVVEGFFQGIIPIGYIVMMAVLLYKITVESGQFLTIQDSITNISQDQRIQVLLIGFAFNAFLEGAAGFGVPIAICALLLTQLGFNPLKAAMLCLVANAASGAFGAIGIPVGVVETLKLPGDVSVLGVSQSATLTLAIINFIIPFLLIFIIDGFRGVKETLPAILVVSITYTLTQGLLTVFSGPELADIIPPLLTMLALAVFSKKFQPKHIYRVNKDEEIEPAKAHSAKAVLHAWSPFIVLTVIVMIWSAPFFKNLFLPNGALSSLVFKFNLPGTISEVTHKPLVLTLNIIGQTGTAILLTIIITILMSKKVNFKDAVRLFGVTFKELWLPVLTICFILAISKITTYGGLSAAMGQGIAKAGNVFPVLSPILGWIGVFMTGSVVNNNSLFAPIQASVAQQIGTSGSLLVSANTVGGVAAKLISPQSIAIATAAVKQVGKESELLKMTLKYSVCLLIFICIWTFILSLL

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator: Rex* (repression) regulon
    Rex*(TF)important in Energy metabolism; RegPrecise 

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]