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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 03-AUG-2016

Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_01520
  • pan locus tag?: SAUPAN001815000
  • symbol: SAOUHSC_01520
  • pan gene symbol?:
  • synonym:
  • product: SLT orf 488-like protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_01520
  • symbol: SAOUHSC_01520
  • product: SLT orf 488-like protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1467209..1468675
  • length: 1467
  • essential: no DEG

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGAGTAATTTAGAGAAATCTGTAGCTATAAATTTAGAAAACACAGCGCATTATGGAAAT
    ATTTCAAATCTAGATATAACTTTTAGAACAGGAGAGAGTGATTCTTCTGTTCTTCTTTTT
    AATATCACTAAAAATAATCAACCGTTATTATTGAGTGAAGAAAATATCAAAGCACGAATA
    GCGATTCGAGGTAAAGGAGTCATGGTAGTTGCTCCACTAGAAATATTAGATCCATTTAAA
    GGTATTTTAAAATTTCAATTACCTAATGATGTAATTAAACGAGATGGAAGTTATCAAGCT
    CAAGTTTCGGTTGCAGAATTAGGTAATTCAGACGTGGTAGTTGTCGAGAGAACTATCACA
    TTTAACGTTGAAAAAAGTTTGTTTAGCATGATTCCATCTGAAACAAAATTACACTATATT
    GTTGAATTTCAGGAATTAGAAAAAACTATTATGGATCGTGCGAAAGCAATGGACGAGGCT
    ATAAAAAATGGTGAAGATTATGCGAGTCTGATTGAAAAAGCTAAAGAAAAAGGTCTATCA
    GATATTCAAATAGCAAAATCTTCAAGTATAGATGAATTAAAGCAACTTGCTAATAGCCAT
    ATATCTGATTTGGAAAATAAAGCGCAAGCATATTCAAGAACATTCGATGAGCAAAAGCGA
    TATATGGATGAGAAACATGAAGCCTTCAAGCAGTCAGTGAATAGTGGTGGTTTAGTCACA
    AGTGGTTCTACTTCAAATTGGCAAAAAGCTAAGATTACTAAAGATGATGGTAAGATAATG
    CAGATTACTGGATTTGATTTTAATAATCCAGAACAAAGAATAGGTGATTCAACCCAATTT
    ATTTATGTTTCGCAAGCTATAAATTATCCAAGAGGTGTTAGTACTAACGGTACTGTCGAA
    TATTTAGTAGTAACTTCAGATTACAAGCGTATGACTTATCGACCGAACGGTACAAATAAA
    GTATTTGTTAAAAGAAAAGAAGCGGGTTCATGGTCTGAGTGGTCAGAATTAGCTATTAAT
    GATTACAATACACCTTTTGAAACTGTTCAAAGTGCCCAATCAAAAGCTAATATGGCCGAA
    AGTAACGCTAAATTATACGCAGATGACAAGTTTAATAAAAGGTATTCGGTTATTTTTGAT
    GGAACAGCAAATGGTGTGGGCTCTACATTGTACTTAAATGAGAGTTTAGACCAATTTATT
    TTATTAATTTTTTATGGGACTTTTCCAGGTGGTGACTTTACAGAGTTTGGCAGTCCTTTT
    GGAGGAGGAAAGATTTCATTGAATCCCTCAAATCTTCCAGATGGTGATGGAAATGGTGGA
    GGTGTTTATGAGTTTGGATTAACTAAATCTAGTCGTACATCTTTAACTATATCAAACGAT
    GTCTATTTCGACTTAGGAAGTCAAAGAGGCTCTGGTGCGAACGCAAATAGAGGGACAATT
    AACAAAATTATAGGAGTGAGAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1467

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAOUHSC_01520
  • symbol: SAOUHSC_01520
  • description: SLT orf 488-like protein
  • length: 488
  • theoretical pI: 5.42313
  • theoretical MW: 53968
  • GRAVY: -0.451639

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Phage protein
  • PFAM:
    no clan defined DUF2479; Domain of unknown function (DUF2479) (PF10651; HMM-score: 108.2)
    and 1 more
    SOAR; STIM1 Orai1-activating region (PF16533; HMM-score: 12.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004797
    • TAT(Tat/SPI): 0.000205
    • LIPO(Sec/SPII): 0.000771
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MSNLEKSVAINLENTAHYGNISNLDITFRTGESDSSVLLFNITKNNQPLLLSEENIKARIAIRGKGVMVVAPLEILDPFKGILKFQLPNDVIKRDGSYQAQVSVAELGNSDVVVVERTITFNVEKSLFSMIPSETKLHYIVEFQELEKTIMDRAKAMDEAIKNGEDYASLIEKAKEKGLSDIQIAKSSSIDELKQLANSHISDLENKAQAYSRTFDEQKRYMDEKHEAFKQSVNSGGLVTSGSTSNWQKAKITKDDGKIMQITGFDFNNPEQRIGDSTQFIYVSQAINYPRGVSTNGTVEYLVVTSDYKRMTYRPNGTNKVFVKRKEAGSWSEWSELAINDYNTPFETVQSAQSKANMAESNAKLYADDKFNKRYSVIFDGTANGVGSTLYLNESLDQFILLIFYGTFPGGDFTEFGSPFGGGKISLNPSNLPDGDGNGGGVYEFGLTKSSRTSLTISNDVYFDLGSQRGSGANANRGTINKIIGVRK

Experimental data[edit | edit source]

  • experimentally validated: data available for COL
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]