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NCBI: 03-AUG-2016

Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_02797
  • pan locus tag?: SAUPAN006099000
  • symbol: SAOUHSC_02797
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_02797
  • symbol: SAOUHSC_02797
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2568432..2569625
  • length: 1194
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGTTGTATTTAGAAGTTTTGAAAAATAGAAACTTTACATATTTATTGATTGGTAATTTC
    TTACGTCGGAGTTGTTTTGTGCTGTTTTCGTTACAAATAATTTGGTTTACTGTTGAATTG
    ACAAACCAATCATCTTTAAAATTATCAATGATGGTTATGAGTCAAACACTTCCATTTATT
    ATATTTGGTATTTTCGGTGGCGCATATTCTGATAAACATAATAAAAAGAAAATACTTTAT
    CTATCTGATCTTATACTAAGTTTGATTATAATAATTATTCCTTTACTTGCAATAACATCA
    AATTTAAATTATCTGACGCTTCTAACCATATCTACAGCTATCACCATTATTAACTGCTAT
    ACGGATCCTGCGTTTAGGGCAATTCTTCCTGAAATTATTGATGAGGAGCATTTAGCAACA
    AGTAATGCGTTAATCGATAGTTTGCAAAGAGGCTCAAATATTATTTTACCTGCTTTAATT
    GGTGTCATTGTAATACTAGTTGGTAATGTTGGCGTCTTTTTTATTTGTAGTATATTGCTA
    TTTTTAGGATTTATTTTTAATGCACTTTTAAAATATACAAATAACAACATGATTGATAGA
    CACTCAAAAGAAGATTTTTCTGAAACTTGGGAATTCTTGAAACAATCTAAAGAAATTCCA
    TTTATTATAATCATCCAATTTGCCTGCATATTGATTAATACTGGCCTTTGGCGTGTTGTA
    TTACCATTGTTTATTTCCAATATATTAAAAGAGGGCGTTGGTGTATATGGACTAGCTACA
    TCATGTTTAGGTATAGCATCTTTATTAATGTCATTGATTATGGGTTTGCTGTCAGAAAAG
    CGATTAATCTTTAAATTTAGTATTGGTGTTTTAGTTTGGGGAATTGGCTTATCGATTATT
    AATGTGTTTCCAAGTGTGGCGATATTATATATAGGTGCAACATTATTGGGACTTGGACAA
    TCTATAGAGGGACTAACAAGATCAGTTGCCATTCAAATAAAAACGCCAAATCATTTGATG
    GGGAAAGTATTTAGTATCTCATCTACATCGAATTATGCAGCGGATACATTGTCTTTAGGA
    CTGATAAGTATAATTATACCTTTACTAAGCTTAAGTAATATATTTATATTAGGAGGTGTA
    ATTATTTCAATACTTAGCTTAGCTGGGTTAAAGTTTGTTAAGAAGTCTATGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1194

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAOUHSC_02797
  • symbol: SAOUHSC_02797
  • description: hypothetical protein
  • length: 397
  • theoretical pI: 9.28776
  • theoretical MW: 43811.3
  • GRAVY: 0.932494

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds H+ Antiporter protein (TIGR00900; HMM-score: 136.1)
    and 1 more
    multidrug resistance protein (TIGR00880; HMM-score: 21.2)
  • TheSEED  :
    • FIG01108030: hypothetical protein
  • PFAM:
    MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 92.2)
    MFS_3; Transmembrane secretion effector (PF05977; HMM-score: 82.9)
    and 1 more
    no clan defined Comm; Commissureless (PF15957; HMM-score: 6.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.013864
    • TAT(Tat/SPI): 0.000358
    • LIPO(Sec/SPII): 0.005988
  • predicted transmembrane helices (TMHMM): 8

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MLYLEVLKNRNFTYLLIGNFLRRSCFVLFSLQIIWFTVELTNQSSLKLSMMVMSQTLPFIIFGIFGGAYSDKHNKKKILYLSDLILSLIIIIIPLLAITSNLNYLTLLTISTAITIINCYTDPAFRAILPEIIDEEHLATSNALIDSLQRGSNIILPALIGVIVILVGNVGVFFICSILLFLGFIFNALLKYTNNNMIDRHSKEDFSETWEFLKQSKEIPFIIIIQFACILINTGLWRVVLPLFISNILKEGVGVYGLATSCLGIASLLMSLIMGLLSEKRLIFKFSIGVLVWGIGLSIINVFPSVAILYIGATLLGLGQSIEGLTRSVAIQIKTPNHLMGKVFSISSTSNYAADTLSLGLISIIIPLLSLSNIFILGGVIISILSLAGLKFVKKSM

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]