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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_1920 [new locus tag: SAUSA300_RS10530 ]
  • pan locus tag?: SAUPAN005020000
  • symbol: chs
  • pan gene symbol?: chp
  • synonym:
  • product: chemotaxis-inhibiting protein CHIPS

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_1920 [new locus tag: SAUSA300_RS10530 ]
  • symbol: chs
  • product: chemotaxis-inhibiting protein CHIPS
  • replicon: chromosome
  • strand: +
  • coordinates: 2086896..2087345
  • length: 450
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAAAAAGAAATTAGCAACAACAGTTTTAGCATTAAGTTTTTTAACGGCAGGAATCAGT
    ACACACCATCATTCAGCGAAAGCTTTTACTTTTGAACCGTTTCCTACAAATGAAGAAATA
    GAATCAAATAAGAAAATGTTAGAGAAAGAAAAAGCTTATAAAGAATCATTTAAAAATAGT
    GGTCTTCCTACAACGCTAGGAAAATTAGATGAACGTTTGAGAAATTATTTAAAGAAAGGC
    ACAAAAAATTCTGCTCAATTTGAAAAAATGGTTATTTTAACTGAAAATAAAGGTTACTAT
    ACAGTATATCTGAATACACCACTTGCTGAAGATAGAAAAAATGTTGAGTTACTAGGTAAA
    ATGTATAAAACATACTTCTTTAAAAAAGGAGAGTCTAAATCATCTTATGTAATTAATGGT
    CCTGGAAAAACTAATGAATATGCATACTAA
    60
    120
    180
    240
    300
    360
    420
    450

Protein[edit | edit source]

Protein Data Bank: 1XEE
Protein Data Bank: 2K3U

General[edit | edit source]

  • locus tag: SAUSA300_1920 [new locus tag: SAUSA300_RS10530 ]
  • symbol: Chs
  • description: chemotaxis-inhibiting protein CHIPS
  • length: 149
  • theoretical pI: 10.1146
  • theoretical MW: 17057.5
  • GRAVY: -0.721476

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Phage protein
  • PFAM:
    Ubiquitin (CL0072) CHIPS; Chemotaxis-inhibiting protein CHIPS (PF11434; HMM-score: 205.8)
    and 1 more
    no clan defined FPRL1_inhibitor; Formyl peptide receptor-like 1 inhibitory protein (PF16104; HMM-score: 13)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 3.33
    • Cellwall Score: 3.33
    • Extracellular Score: 3.33
    • Internal Helices: 0
  • LocateP: Secretory(released) (with CS)
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: -0.17
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: HSAKAFTF
  • SignalP: Signal peptide SP(Sec/SPI) length 28 aa
    • SP(Sec/SPI): 0.985782
    • TAT(Tat/SPI): 0.002222
    • LIPO(Sec/SPII): 0.010792
    • Cleavage Site: CS pos: 28-29. AKA-FT. Pr: 0.9512
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKKKLATTVLALSFLTAGISTHHHSAKAFTFEPFPTNEEIESNKKMLEKEKAYKESFKNSGLPTTLGKLDERLRNYLKKGTKNSAQFEKMVILTENKGYYTVYLNTPLAEDRKNVELLGKMYKTYFFKKGESKSSYVINGPGKTNEYAY

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]