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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS11435 [old locus tag: SAUSA300_2077 ]
  • pan locus tag?: SAUPAN005415000
  • symbol: SAUSA300_RS11435
  • pan gene symbol?: qsrR
  • synonym:
  • product: transcriptional regulator

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS11435 [old locus tag: SAUSA300_2077 ]
  • symbol: SAUSA300_RS11435
  • product: transcriptional regulator
  • replicon: chromosome
  • strand: -
  • coordinates: 2239280..2239615
  • length: 336
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGGAAGTATGTCCGTATCTCGAAGAAACTTTTAAAATACTTGGTAGAAGTTGGAATGGA
    TTAATCATTAATTATCTCTCAAGATGTAATGACTGTTCAGCACACTTTTCCGATATGAAA
    AGAGATTTGAAAACAATAACACCACGTGCTTTAAGTCTTAAGTTGTCAGAGCTTGCACAA
    TGGGAGTTAGTTGAGAAGCAAATCATTTCTACGAGTCCAGTACAAATTATTTATGTGCTA
    ACTGAAAAAGGTAAAGCGTTAGCAGAGGCTTTACATCCAATTGAAGCATGGGCGCAATCA
    TATGTCGATTTAACAGATCAACGTACTGCTAAATAA
    60
    120
    180
    240
    300
    336

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_RS11435 [old locus tag: SAUSA300_2077 ]
  • symbol: SAUSA300_RS11435
  • description: transcriptional regulator
  • length: 111
  • theoretical pI: 6.50773
  • theoretical MW: 12685.6
  • GRAVY: -0.152252

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SAUSA300_2077
  • PFAM:
    HTH (CL0123) HxlR; HxlR-like helix-turn-helix (PF01638; HMM-score: 61.6)
    and 3 more
    HTH_34; Winged helix DNA-binding domain (PF13601; HMM-score: 15.2)
    Replic_Relax; Replication-relaxation (PF13814; HMM-score: 13.4)
    HTH_45; Winged helix-turn-helix (PF14947; HMM-score: 12.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.012963
    • TAT(Tat/SPI): 0.00073
    • LIPO(Sec/SPII): 0.026121
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MEVCPYLEETFKILGRSWNGLIINYLSRCNDCSAHFSDMKRDLKTITPRALSLKLSELAQWELVEKQIISTSPVQIIYVLTEKGKALAEALHPIEAWAQSYVDLTDQRTAK

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]