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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS12365 [old locus tag: SA2153 ]
  • pan locus tag?: SAUPAN005872000
  • symbol: SA_RS12365
  • pan gene symbol?:
  • synonym:
  • product: LytTR family transcriptional regulator

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS12365 [old locus tag: SA2153 ]
  • symbol: SA_RS12365
  • product: LytTR family transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 2419117..2419560
  • length: 444
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (2419117..2419560) NCBI
  • BioCyc: G1G21-2508 BioCyc
  • MicrobesOnline: see SA2153

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGATGAAACTCAATTTATTTATCAATGCAAATGAGACGGAATCTTATATTGATATACAT
    GCACCTAAAATGAATGATCACGTTCAAAGTATTATTAATGCAGTCAATGATTTAGACAAA
    TCACATACATTAGTCGGATACATAGACAAAGAAATCCATATCATTAATGTATCAGATGTT
    ATAACATTCCAAGTTATTAATAAAAATGTAACAGCCATTACAAGCAATCAAAAATTCAAA
    CTAAAATTACGACTTTATGAACTAGAAAAACAGTTACCACAACATTTCATTCGCATTTCC
    AAATCAGAAATCGTCAACAAGTATTACATTGAAAAATTATTATTAGAGCCAAATGGACTT
    ATACGTATGTATCTTAAAGATGCACACTACACCTATTCTTCTAGACGTTATTTAAAATCT
    ATAAAGGAGCGCTTATCAATATGA
    60
    120
    180
    240
    300
    360
    420
    444

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS12365 [old locus tag: SA2153 ]
  • symbol: SA_RS12365
  • description: LytTR family transcriptional regulator
  • length: 147
  • theoretical pI: 9.75724
  • theoretical MW: 17339.1
  • GRAVY: -0.291156

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SA2153
  • PFAM:
    Tudor (CL0049) LytTR; LytTr DNA-binding domain (PF04397; HMM-score: 76.6)
    and 1 more
    no clan defined Cnn_1N; Centrosomin N-terminal motif 1 (PF07989; HMM-score: 14.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003281
    • TAT(Tat/SPI): 0.000101
    • LIPO(Sec/SPII): 0.000389
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MMKLNLFINANETESYIDIHAPKMNDHVQSIINAVNDLDKSHTLVGYIDKEIHIINVSDVITFQVINKNVTAITSNQKFKLKLRLYELEKQLPQHFIRISKSEIVNKYYIEKLLLEPNGLIRMYLKDAHYTYSSRRYLKSIKERLSI

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]